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Impaired visually enhanced vestibulo-ocular reflex

MedGen UID:
866700
Concept ID:
C4021047
Finding
Synonyms: Visually enhanced vestibulo-ocular reflex impairment; VVOR impairment
 
HPO: HP:0030183

Definition

The vestibulo-ocular reflex is responsible for the stabilization of the retinal image during movement. The visual vestibular ocular reflex (VVOR) or visual enhanced VOR, maintains ocular stability during head motion by generating compensatory eye movement opposite to head movement, and is a major component of visual vestibular interaction. This feature is an impairment of this reflex, manifested as the combined impairment of the three compensatory eye movement reflexes, namely the vestibulo-ocular reflex (VOR), smooth pursuit (SP) and optokinetic reflex (OKR). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVImpaired visually enhanced vestibulo-ocular reflex

Professional guidelines

PubMed

Szmulewicz DJ, McLean CA, MacDougall HG, Roberts L, Storey E, Halmagyi GM
J Vestib Res 2014;24(5-6):465-74. doi: 10.3233/VES-140536. PMID: 25564090

Recent clinical studies

Etiology

Hassannia F, Misale P, Sulway S, Olmos GV, Dabiri S, Ranalli P, Rutka JA
J Vestib Res 2022;32(5):479-485. doi: 10.3233/VES-210058. PMID: 35527586
Stephen CD, Balkwill D, James P, Haxton E, Sassower K, Schmahmann JD, Eichler F, Lewis R
Neurology 2020 Feb 18;94(7):e705-e717. Epub 2020 Jan 21 doi: 10.1212/WNL.0000000000008959. PMID: 31964693Free PMC Article
Almutairi A, Cochrane GD, Christy JB
Int J Pediatr Otorhinolaryngol 2019 Apr;119:15-21. Epub 2019 Jan 2 doi: 10.1016/j.ijporl.2018.12.038. PMID: 30660854
Cheng RC, Walker MF
J Vestib Res 2016;26(5-6):417-423. doi: 10.3233/VES-160596. PMID: 28262645
Szmulewicz DJ, McLean CA, MacDougall HG, Roberts L, Storey E, Halmagyi GM
J Vestib Res 2014;24(5-6):465-74. doi: 10.3233/VES-140536. PMID: 25564090

Diagnosis

Hassannia F, Misale P, Sulway S, Olmos GV, Dabiri S, Ranalli P, Rutka JA
J Vestib Res 2022;32(5):479-485. doi: 10.3233/VES-210058. PMID: 35527586
Stephen CD, Balkwill D, James P, Haxton E, Sassower K, Schmahmann JD, Eichler F, Lewis R
Neurology 2020 Feb 18;94(7):e705-e717. Epub 2020 Jan 21 doi: 10.1212/WNL.0000000000008959. PMID: 31964693Free PMC Article
Bronstein AM
Handb Clin Neurol 2016;137:57-66. doi: 10.1016/B978-0-444-63437-5.00004-2. PMID: 27638062
Szmulewicz DJ, McLean CA, MacDougall HG, Roberts L, Storey E, Halmagyi GM
J Vestib Res 2014;24(5-6):465-74. doi: 10.3233/VES-140536. PMID: 25564090
Petersen JA, Wichmann WW, Weber KP
Neurology 2013 Oct 29;81(18):1642-3. doi: 10.1212/WNL.0b013e3182a9f435. PMID: 24166963

Therapy

Cheng RC, Walker MF
J Vestib Res 2016;26(5-6):417-423. doi: 10.3233/VES-160596. PMID: 28262645

Prognosis

Hassannia F, Misale P, Sulway S, Olmos GV, Dabiri S, Ranalli P, Rutka JA
J Vestib Res 2022;32(5):479-485. doi: 10.3233/VES-210058. PMID: 35527586
Grant MP, Leigh RJ, Seidman SH, Riley DE, Hanna JP
Brain 1992 Oct;115 ( Pt 5):1323-42. doi: 10.1093/brain/115.5.1323. PMID: 1422791

Clinical prediction guides

Kim HJ, Kim HJ, Lee JH, Kim JS
Neurology 2023 Jan 3;100(1):43-46. Epub 2022 Oct 3 doi: 10.1212/WNL.0000000000201466. PMID: 36192172
Hassannia F, Misale P, Sulway S, Olmos GV, Dabiri S, Ranalli P, Rutka JA
J Vestib Res 2022;32(5):479-485. doi: 10.3233/VES-210058. PMID: 35527586
Almutairi A, Cochrane GD, Christy JB
Int J Pediatr Otorhinolaryngol 2019 Apr;119:15-21. Epub 2019 Jan 2 doi: 10.1016/j.ijporl.2018.12.038. PMID: 30660854
Anson ER, Kiemel T, Carey JP, Jeka JJ
J Assoc Res Otolaryngol 2017 Aug;18(4):591-600. Epub 2017 Jun 7 doi: 10.1007/s10162-017-0626-8. PMID: 28593438Free PMC Article
Grant MP, Leigh RJ, Seidman SH, Riley DE, Hanna JP
Brain 1992 Oct;115 ( Pt 5):1323-42. doi: 10.1093/brain/115.5.1323. PMID: 1422791

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