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Midline sinus of philtrum

MedGen UID:
866765
•Concept ID:
C4021116
•
Anatomical Abnormality
Synonyms: Central sinus of philtrum; Philtrum, Midline Sinus
 
HPO: HP:0011828

Definition

Pit in the midline of the philtral groove. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMidline sinus of philtrum

Recent clinical studies

Etiology

Congenital midline upper lip sinuses with intracranial extension - A variant of nasal dermoid? An embryology-based concept.
Kotowski M, Szydlowski J
Int J Pediatr Otorhinolaryngol 2023 Jan;164:111394. Epub 2022 Nov 19 doi: 10.1016/j.ijporl.2022.111394. PMID: 36459726
Congenital Midline Upper Lip Sinuses: 3 Rare Cases.
Kün-Darbois JD, Chatellier A, Paré A, Caillot A, Ambroise B, Bénateau H, Veyssière A
Cleft Palate Craniofac J 2018 Feb;55(2):292-295. Epub 2017 Dec 14 doi: 10.1177/1055665617723635. PMID: 29351043
Unusual variants of midline nasal dermoid cysts: a series of three cases.
Locke R, Kubba H
J Laryngol Otol 2012 Jan;126(1):83-7. Epub 2011 Nov 4 doi: 10.1017/S0022215111002891. PMID: 22051034
The external rhinoplasty approach for rhinologic surgery in children.
Koltai PJ, Hoehn J, Bailey CM
Arch Otolaryngol Head Neck Surg 1992 Apr;118(4):401-5. doi: 10.1001/archotol.1992.01880040063011. PMID: 1554470
Congenital midline cervical cleft.
Bergevin MA, Sheft S, Myer C 3rd, McAdams AJ
Pediatr Pathol 1989;9(6):731-9. doi: 10.3109/15513818909022380. PMID: 2602229

Diagnosis

Nasofrontal dermoid cyst: rare presentation of a philtrum sinus.
Donnell CC, McKeague KF, Cooper A, Stenhouse J
Br J Oral Maxillofac Surg 2020 Jun;58(5):608-610. Epub 2020 Mar 20 doi: 10.1016/j.bjoms.2020.03.004. PMID: 32201047
Ultrasound Evaluation of Dermal Sinuses/Fistulas in Pediatric Patients.
Hosokawa T, Takahashi H, Miyasaka Y, Ohira K, Tanami Y, Sato Y, Ishimaru T, Kawashima H, Hosokawa M, Oguma E, Yamada Y
J Ultrasound Med 2019 Dec;38(12):3107-3122. Epub 2019 May 7 doi: 10.1002/jum.15016. PMID: 31063247
A More Favorable Lower-Lip Incision for the Removal of Deep Intraoral Malignancies.
Xiang XW, Feng da J, Chen X, Chen CJ
J Craniofac Surg 2016 May;27(3):e228-9. doi: 10.1097/SCS.0000000000002360. PMID: 27159868
Dermoid sinus and cyst of the lip.
Kormanik KE, Bersu ET, Bentz ML
J Craniofac Surg 2006 Jan;17(1):162-6. doi: 10.1097/01.scs.0000168997.12634.16. PMID: 16432426
The face does predict the brain--midline facial and forebrain defects uncovered during the investigation of nasal obstruction and rhinorrhea. Case report and a review of holoprosencephaly and its classifications.
El-Hawrani A, Sohn M, Noga M, El-Hakim H
Int J Pediatr Otorhinolaryngol 2006 May;70(5):935-40. Epub 2005 Nov 8 doi: 10.1016/j.ijporl.2005.09.020. PMID: 16280170

Therapy

Infraorbital nerve block in children: a computerized tomographic measurement of the location of the infraorbital foramen.
Suresh S, Voronov P, Curran J
Reg Anesth Pain Med 2006 May-Jun;31(3):211-4. doi: 10.1016/j.rapm.2005.11.017. PMID: 16701185
A new surgical approach to extensive tumors in the pterygomaxillary fossa and the skull base.
Jian XC, Liu JP
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003 Feb;95(2):156-62. doi: 10.1067/moe.2003.41. PMID: 12582354
Nasolabial esthetics after Le Fort I osteotomy and V-Y closure: a statistical evaluation.
Rosenberg A, Muradin MS, van der Bilt A
Int J Adult Orthodon Orthognath Surg 2002;17(1):29-39. PMID: 11934053

Prognosis

Infraorbital nerve block in children: a computerized tomographic measurement of the location of the infraorbital foramen.
Suresh S, Voronov P, Curran J
Reg Anesth Pain Med 2006 May-Jun;31(3):211-4. doi: 10.1016/j.rapm.2005.11.017. PMID: 16701185
The face does predict the brain--midline facial and forebrain defects uncovered during the investigation of nasal obstruction and rhinorrhea. Case report and a review of holoprosencephaly and its classifications.
El-Hawrani A, Sohn M, Noga M, El-Hakim H
Int J Pediatr Otorhinolaryngol 2006 May;70(5):935-40. Epub 2005 Nov 8 doi: 10.1016/j.ijporl.2005.09.020. PMID: 16280170
Congenital sinus of the upper lip with idiopathic precocious puberty.
Sumitomo S, Ogawa S, Hirai K, Takai Y
Oral Dis 2002 Nov;8(6):308-9. doi: 10.1034/j.1601-0825.2002.02871.x. PMID: 12477063
Rhinologic computed tomographic evaluation in patients with cleft lip and palate.
Suzuki H, Yamaguchi T, Furukawa M
Arch Otolaryngol Head Neck Surg 1999 Sep;125(9):1000-4. doi: 10.1001/archotol.125.9.1000. PMID: 10488986
Congenital midline cervical cleft.
Bergevin MA, Sheft S, Myer C 3rd, McAdams AJ
Pediatr Pathol 1989;9(6):731-9. doi: 10.3109/15513818909022380. PMID: 2602229

Clinical prediction guides

Infraorbital nerve block in children: a computerized tomographic measurement of the location of the infraorbital foramen.
Suresh S, Voronov P, Curran J
Reg Anesth Pain Med 2006 May-Jun;31(3):211-4. doi: 10.1016/j.rapm.2005.11.017. PMID: 16701185
The face does predict the brain--midline facial and forebrain defects uncovered during the investigation of nasal obstruction and rhinorrhea. Case report and a review of holoprosencephaly and its classifications.
El-Hawrani A, Sohn M, Noga M, El-Hakim H
Int J Pediatr Otorhinolaryngol 2006 May;70(5):935-40. Epub 2005 Nov 8 doi: 10.1016/j.ijporl.2005.09.020. PMID: 16280170
Congenital sinus of the upper lip with idiopathic precocious puberty.
Sumitomo S, Ogawa S, Hirai K, Takai Y
Oral Dis 2002 Nov;8(6):308-9. doi: 10.1034/j.1601-0825.2002.02871.x. PMID: 12477063
Nasolabial esthetics after Le Fort I osteotomy and V-Y closure: a statistical evaluation.
Rosenberg A, Muradin MS, van der Bilt A
Int J Adult Orthodon Orthognath Surg 2002;17(1):29-39. PMID: 11934053

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