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Hyperpigmentation of the fundus

MedGen UID:
866794
Concept ID:
C4021146
Finding
Synonyms: Hyperpigmented fundi; Hyperpigmented fundus
 
HPO: HP:0011512

Definition

Increased pigmentation of the fundus [from HPO]

Professional guidelines

PubMed

Biarnés M, Colijn JM, Sousa J, Ferraro LL, Garcia M, Verzijden T, Meester-Smoor MA, Delcourt C, Klaver CCW, den Hollander AI, Lengyel I, Peto T, Monés J; EYE-RISK Consortium
Ophthalmol Retina 2020 Dec;4(12):1129-1137. Epub 2020 May 1 doi: 10.1016/j.oret.2020.04.014. PMID: 32371126
Neely DC, Bray KJ, Huisingh CE, Clark ME, McGwin G Jr, Owsley C
JAMA Ophthalmol 2017 Jun 1;135(6):570-575. doi: 10.1001/jamaophthalmol.2017.0830. PMID: 28448669Free PMC Article
Gündüz K, Pulido JS, Bakri SJ, Amselem L, Petit-Fond E, Link T
Trans Am Ophthalmol Soc 2007;105:172-8; discussion 178-9. PMID: 18427607Free PMC Article

Recent clinical studies

Etiology

Huang S, Yang Y, Ouyang Z, Guo X, Zhan Z, Liu X, Chen Z, Xu J, Yu M
Eur J Dermatol 2022 Sep 1;32(5):589-596. doi: 10.1684/ejd.2022.4317. PMID: 36468718
Venkatesh R, Reddy N, Cherry JP, Pereira A, Yadav NK, Chhablani J
Eur J Ophthalmol 2022 Nov;32(6):NP41-NP46. Epub 2021 May 20 doi: 10.1177/11206721211019573. PMID: 34015946
Elsner AE, Papay JA, Johnston KD, Sawides L, de Castro A, King BJ, Jones DW, Clark CA, Gast TJ, Burns SA
Ophthalmic Physiol Opt 2020 Mar;40(2):88-116. Epub 2020 Feb 4 doi: 10.1111/opo.12670. PMID: 32017191Free PMC Article
Pauleikhoff D, Koch JM
Curr Opin Ophthalmol 1995 Jun;6(3):51-6. doi: 10.1097/00055735-199506000-00009. PMID: 10150870
De Laey JJ
Bull Soc Belge Ophtalmol 1993;249:11-22. PMID: 7952338

Diagnosis

Huang S, Yang Y, Ouyang Z, Guo X, Zhan Z, Liu X, Chen Z, Xu J, Yu M
Eur J Dermatol 2022 Sep 1;32(5):589-596. doi: 10.1684/ejd.2022.4317. PMID: 36468718
Venkatesh R, Reddy N, Cherry JP, Pereira A, Yadav NK, Chhablani J
Eur J Ophthalmol 2022 Nov;32(6):NP41-NP46. Epub 2021 May 20 doi: 10.1177/11206721211019573. PMID: 34015946
Tsang SH, Sharma T
Adv Exp Med Biol 2018;1085:153-156. doi: 10.1007/978-3-319-95046-4_28. PMID: 30578501
B S G, Pai GS, Pai AH, Vinekar AS, Pai HS, Noronha T, Fernandes MS
Kathmandu Univ Med J (KUMJ) 2013 Jan-Mar;11(41):91-3. doi: 10.3126/kumj.v11i1.11052. PMID: 23774424
De Laey JJ
Bull Soc Belge Ophtalmol 1993;249:11-22. PMID: 7952338

Therapy

Hess K, Park YJ, Kim HA, Holz FG, Charbel Issa P, Yoon YH, Tzaridis S
Ophthalmol Retina 2023 Feb;7(2):101-110. Epub 2022 Aug 7 doi: 10.1016/j.oret.2022.08.004. PMID: 35948211
Pearce WA, Chen R, Jain N
Ophthalmology 2018 Nov;125(11):1793-1802. Epub 2018 May 22 doi: 10.1016/j.ophtha.2018.04.026. PMID: 29801663
Kim JH, Chang YS, Kim CG, Lee DW, Han JI
Graefes Arch Clin Exp Ophthalmol 2018 Mar;256(3):469-477. Epub 2018 Jan 4 doi: 10.1007/s00417-017-3877-5. PMID: 29302789
Jung JJ, Chen MH, Sorenson AL, Rofagha S
Ophthalmic Surg Lasers Imaging Retina 2016 Apr 1;47(4):356-61. doi: 10.3928/23258160-20160324-09. PMID: 27065376
Daniel E, Toth CA, Grunwald JE, Jaffe GJ, Martin DF, Fine SL, Huang J, Ying GS, Hagstrom SA, Winter K, Maguire MG; Comparison of Age-related Macular Degeneration Treatments Trials Research Group
Ophthalmology 2014 Mar;121(3):656-66. Epub 2013 Dec 4 doi: 10.1016/j.ophtha.2013.10.019. PMID: 24314839Free PMC Article

Prognosis

Huang S, Yang Y, Ouyang Z, Guo X, Zhan Z, Liu X, Chen Z, Xu J, Yu M
Eur J Dermatol 2022 Sep 1;32(5):589-596. doi: 10.1684/ejd.2022.4317. PMID: 36468718
Mueller S, Gunnemann F, Rothaus K, Book M, Faatz H, Bird A, Pauleikhoff D
Br J Ophthalmol 2021 Apr;105(4):573-576. Epub 2021 Jan 7 doi: 10.1136/bjophthalmol-2020-317997. PMID: 33414243
Mano F, Sprehe N, Olsen TW
Ophthalmol Retina 2021 Aug;5(8):743-749. Epub 2020 Nov 20 doi: 10.1016/j.oret.2020.11.011. PMID: 33227563
North V, Gelman R, Tsang SH
Dev Ophthalmol 2014;53:44-52. Epub 2014 Apr 10 doi: 10.1159/000357293. PMID: 24732760Free PMC Article
Daniel E, Toth CA, Grunwald JE, Jaffe GJ, Martin DF, Fine SL, Huang J, Ying GS, Hagstrom SA, Winter K, Maguire MG; Comparison of Age-related Macular Degeneration Treatments Trials Research Group
Ophthalmology 2014 Mar;121(3):656-66. Epub 2013 Dec 4 doi: 10.1016/j.ophtha.2013.10.019. PMID: 24314839Free PMC Article

Clinical prediction guides

Huang S, Yang Y, Ouyang Z, Guo X, Zhan Z, Liu X, Chen Z, Xu J, Yu M
Eur J Dermatol 2022 Sep 1;32(5):589-596. doi: 10.1684/ejd.2022.4317. PMID: 36468718
Venkatesh R, Reddy N, Cherry JP, Pereira A, Yadav NK, Chhablani J
Eur J Ophthalmol 2022 Nov;32(6):NP41-NP46. Epub 2021 May 20 doi: 10.1177/11206721211019573. PMID: 34015946
Francis JH, Habib LA, Abramson DH
Br J Ophthalmol 2018 Jan;102(1):120-125. Epub 2017 Jun 16 doi: 10.1136/bjophthalmol-2017-310406. PMID: 28625971Free PMC Article
Gündüz K, Pulido JS, Ezzat K, Salomao D, Hann C
Eye (Lond) 2009 Mar;23(3):497-503. Epub 2008 Aug 1 doi: 10.1038/eye.2008.244. PMID: 18670456
De Laey JJ
Bull Soc Belge Ophtalmol 1993;249:11-22. PMID: 7952338

Recent systematic reviews

Huang S, Yang Y, Ouyang Z, Guo X, Zhan Z, Liu X, Chen Z, Xu J, Yu M
Eur J Dermatol 2022 Sep 1;32(5):589-596. doi: 10.1684/ejd.2022.4317. PMID: 36468718

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