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1-5 toe syndactyly

MedGen UID:
866880
Concept ID:
C4021235
Congenital Abnormality
Synonyms: Syndactyly of all toes; Webbed 1st-5th toes
 
HPO: HP:0010713

Definition

Syndactyly with fusion of toes one to five (complete syndactyly of all toes of the foot). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGV1-5 toe syndactyly

Conditions with this feature

Polysyndactyly 4
MedGen UID:
357420
Concept ID:
C1868111
Congenital Abnormality
Although both preaxial polydactyly and syndactyly are cardinal features of this malformation, it is classified as a form of polydactyly because syndactyly does not occur in the absence of polydactyly (McClintic, 1935), the opposite not being true. On the other hand, polysyndactyly is here classified as a type of syndactyly because polydactyly (of the third or fourth fingers and fifth toes) does not occur in the absence of syndactyly. The thumb shows only the mildest degree of duplication, and syndactyly of various degrees affects fingers 3 and 4. The foot malformation is more constant and consists of duplication of part or all of the first or second toes and syndactyly affects all of the toes, especially the second and third.

Recent clinical studies

Etiology

Horlenko O, Lenchenko A, Kossey G, Tomey A, Debretseni O
Georgian Med News 2018 Dec;(285):47-51. PMID: 30702069
Kawabata H, Tamura D
J Hand Surg Am 2018 May;43(5):485.e1-485.e5. Epub 2017 Dec 6 doi: 10.1016/j.jhsa.2017.10.034. PMID: 29223628

Diagnosis

Horlenko O, Lenchenko A, Kossey G, Tomey A, Debretseni O
Georgian Med News 2018 Dec;(285):47-51. PMID: 30702069

Therapy

Horlenko O, Lenchenko A, Kossey G, Tomey A, Debretseni O
Georgian Med News 2018 Dec;(285):47-51. PMID: 30702069

Prognosis

Kawabata H, Tamura D
J Hand Surg Am 2018 May;43(5):485.e1-485.e5. Epub 2017 Dec 6 doi: 10.1016/j.jhsa.2017.10.034. PMID: 29223628

Clinical prediction guides

Chen W, Chen L, Huang W, Tian X
Ann Plast Surg 2021 Mar 1;86(3):323-328. doi: 10.1097/SAP.0000000000002437. PMID: 32568755
Bovendeert JFM, Nievelstein RAJ, Bleys RLAW, Cleypool CGJ
J Med Case Rep 2020 Oct 3;14(1):176. doi: 10.1186/s13256-020-02501-x. PMID: 33008470Free PMC Article

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