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Bilateral breast hypoplasia

MedGen UID:
868322
•Concept ID:
C4022716
•
Anatomical Abnormality
Synonym: Two underdeveloped breasts
 
HPO: HP:0012814

Definition

Underdevelopment of the breast on both sides. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBilateral breast hypoplasia

Professional guidelines

PubMed

Focal white matter microstructural alteration after anthracycline-based systemic treatment in long-term breast cancer survivors: a structural magnetic resonance imaging study.
Zhang H, Li P, Liu T, Wang X, Feng W, Chen R, Wei H, Li G, Ning L, Zhang M, Zhang Y
Brain Imaging Behav 2022 Apr;16(2):843-854. Epub 2021 Oct 4 doi: 10.1007/s11682-021-00551-3. PMID: 34608574
Evaluation of expert criteria for preoperative magnetic resonance imaging of newly diagnosed breast cancer.
Behrendt CE, Tumyan L, Gonser L, Shaw SL, Vora L, Paz IB, Ellenhorn JD, Yim JH
Breast 2014 Aug;23(4):341-5. Epub 2014 Feb 14 doi: 10.1016/j.breast.2014.01.005. PMID: 24530008Free PMC Article
Clear evidence that long-term, low-dose tamoxifen treatment can induce ocular toxicity. A prospective study of 63 patients.
Pavlidis NA, Petris C, Briassoulis E, Klouvas G, Psilas C, Rempapis J, Petroutsos G
Cancer 1992 Jun 15;69(12):2961-4. doi: 10.1002/1097-0142(19920615)69:12<2961::aid-cncr2820691215>3.0.co;2-w. PMID: 1591689

Recent clinical studies

Etiology

BREAST-Q Outcomes before and after Bilateral Reduction Mammaplasty.
Wampler AT, Powelson IA, Homa K, Freed GL
Plast Reconstr Surg 2021 Mar 1;147(3):382e-390e. doi: 10.1097/PRS.0000000000007605. PMID: 33620922
Incidence and tumour characteristics of bilateral and unilateral interval breast cancers at screening mammography.
van Bommel RMG, Voogd AC, Nederend J, Setz-Pels W, Louwman MWJ, Strobbe LJ, Venderink D, Tjan-Heijnen VCG, Duijm LEM
Breast 2018 Apr;38:101-106. Epub 2018 Jan 4 doi: 10.1016/j.breast.2017.12.018. PMID: 29306176
Comprehensive management of congenital choanal atresia.
Brihaye P, Delpierre I, De Villé A, Johansson AB, Biarent D, Mansbach AL
Int J Pediatr Otorhinolaryngol 2017 Jul;98:9-18. Epub 2017 Apr 17 doi: 10.1016/j.ijporl.2017.04.022. PMID: 28583512
Imaging features of bilateral breast abnormalities.
Park SB, Jeong AK, Lee JH, Paeng MH, Lee KS, Cho BJ, Kim HH
Clin Imaging 2011 Mar-Apr;35(2):108-15. doi: 10.1016/j.clinimag.2009.12.024. PMID: 21377048
Breast asymmetries: a brief review and our experience.
Araco A, Gravante G, Araco F, Gentile P, Castrì F, Delogu D, Filingeri V, Cervelli V
Aesthetic Plast Surg 2006 May-Jun;30(3):309-19. doi: 10.1007/s00266-005-0178-x. PMID: 16733775

Diagnosis

Fabrication and evaluation of bilateral Helmholtz radiofrequency coil for thermo-stable breast image with reduced artifacts.
Lee YH, Song KH, Yang J, Kang WJ, Lee KS, Kim MJ, Kim EK, Heo D, Choe BY, Suh JS
J Appl Clin Med Phys 2022 Jan;23(1):e13483. Epub 2021 Dec 1 doi: 10.1002/acm2.13483. PMID: 34854217Free PMC Article
BREAST-Q Outcomes before and after Bilateral Reduction Mammaplasty.
Wampler AT, Powelson IA, Homa K, Freed GL
Plast Reconstr Surg 2021 Mar 1;147(3):382e-390e. doi: 10.1097/PRS.0000000000007605. PMID: 33620922
Effects of bilateral breast reduction on peak airway pressure and pulmonary function tests.
Onuk AA, Senen D, Arslan B, Muslu U, Tek M, Karslı B
Niger J Clin Pract 2018 Aug;21(8):949-953. doi: 10.4103/1119-3077.238420. PMID: 30073993
Incidence and tumour characteristics of bilateral and unilateral interval breast cancers at screening mammography.
van Bommel RMG, Voogd AC, Nederend J, Setz-Pels W, Louwman MWJ, Strobbe LJ, Venderink D, Tjan-Heijnen VCG, Duijm LEM
Breast 2018 Apr;38:101-106. Epub 2018 Jan 4 doi: 10.1016/j.breast.2017.12.018. PMID: 29306176
Imaging features of bilateral breast abnormalities.
Park SB, Jeong AK, Lee JH, Paeng MH, Lee KS, Cho BJ, Kim HH
Clin Imaging 2011 Mar-Apr;35(2):108-15. doi: 10.1016/j.clinimag.2009.12.024. PMID: 21377048

Therapy

A Novel Approach for Tuberous Breast Correction Using Power-Assisted Liposuction, Loops, and Lipofilling (PALLL).
Abboud MH, Abboud NM, El Hajj H
Aesthet Surg J 2022 Oct 13;42(11):NP613-NP629. doi: 10.1093/asj/sjac044. PMID: 35275983
Electrophysiological and phenotypic profiles of taxane-induced neuropathy.
Timmins HC, Li T, Huynh W, Kiernan MC, Baron-Hay S, Boyle F, Goldstein D, Park SB
Clin Neurophysiol 2020 Aug;131(8):1979-1985. Epub 2020 Apr 2 doi: 10.1016/j.clinph.2020.02.028. PMID: 32291143
Effects of bilateral breast reduction on peak airway pressure and pulmonary function tests.
Onuk AA, Senen D, Arslan B, Muslu U, Tek M, Karslı B
Niger J Clin Pract 2018 Aug;21(8):949-953. doi: 10.4103/1119-3077.238420. PMID: 30073993
Comprehensive management of congenital choanal atresia.
Brihaye P, Delpierre I, De Villé A, Johansson AB, Biarent D, Mansbach AL
Int J Pediatr Otorhinolaryngol 2017 Jul;98:9-18. Epub 2017 Apr 17 doi: 10.1016/j.ijporl.2017.04.022. PMID: 28583512
Antidepressant-selective gynecomastia.
Kaufman KR, Podolsky D, Greenman D, Madraswala R
Ann Pharmacother 2013 Jan;47(1):e6. Epub 2013 Jan 16 doi: 10.1345/aph.1R491. PMID: 23324513

Prognosis

BREAST-Q Outcomes before and after Bilateral Reduction Mammaplasty.
Wampler AT, Powelson IA, Homa K, Freed GL
Plast Reconstr Surg 2021 Mar 1;147(3):382e-390e. doi: 10.1097/PRS.0000000000007605. PMID: 33620922
Incidence and tumour characteristics of bilateral and unilateral interval breast cancers at screening mammography.
van Bommel RMG, Voogd AC, Nederend J, Setz-Pels W, Louwman MWJ, Strobbe LJ, Venderink D, Tjan-Heijnen VCG, Duijm LEM
Breast 2018 Apr;38:101-106. Epub 2018 Jan 4 doi: 10.1016/j.breast.2017.12.018. PMID: 29306176
Comprehensive management of congenital choanal atresia.
Brihaye P, Delpierre I, De Villé A, Johansson AB, Biarent D, Mansbach AL
Int J Pediatr Otorhinolaryngol 2017 Jul;98:9-18. Epub 2017 Apr 17 doi: 10.1016/j.ijporl.2017.04.022. PMID: 28583512
Occult Histopathology and Its Predictors in Contralateral and Bilateral Prophylactic Mastectomies.
Mattos D, Gfrerer L, Ling IT, Reish RG, Hughes KS, Halpern EF, Cetrulo C, Colwell AS, Winograd JM, Yaremchuk MJ, Austen WG Jr, Liao EC
Ann Surg Oncol 2016 Mar;23(3):767-75. Epub 2015 Nov 17 doi: 10.1245/s10434-015-4896-2. PMID: 26577123
Breast asymmetries: a brief review and our experience.
Araco A, Gravante G, Araco F, Gentile P, Castrì F, Delogu D, Filingeri V, Cervelli V
Aesthetic Plast Surg 2006 May-Jun;30(3):309-19. doi: 10.1007/s00266-005-0178-x. PMID: 16733775

Clinical prediction guides

A Novel Approach for Tuberous Breast Correction Using Power-Assisted Liposuction, Loops, and Lipofilling (PALLL).
Abboud MH, Abboud NM, El Hajj H
Aesthet Surg J 2022 Oct 13;42(11):NP613-NP629. doi: 10.1093/asj/sjac044. PMID: 35275983
BREAST-Q Outcomes before and after Bilateral Reduction Mammaplasty.
Wampler AT, Powelson IA, Homa K, Freed GL
Plast Reconstr Surg 2021 Mar 1;147(3):382e-390e. doi: 10.1097/PRS.0000000000007605. PMID: 33620922
Male patients with unilateral breast symptoms: an optimal imaging approach.
Yoon B, Chae EY, Cha JH, Shin HJ, Choi WJ, Kim HH
Eur Radiol 2020 Aug;30(8):4242-4250. Epub 2020 Apr 3 doi: 10.1007/s00330-020-06828-3. PMID: 32242274
Occult Histopathology and Its Predictors in Contralateral and Bilateral Prophylactic Mastectomies.
Mattos D, Gfrerer L, Ling IT, Reish RG, Hughes KS, Halpern EF, Cetrulo C, Colwell AS, Winograd JM, Yaremchuk MJ, Austen WG Jr, Liao EC
Ann Surg Oncol 2016 Mar;23(3):767-75. Epub 2015 Nov 17 doi: 10.1245/s10434-015-4896-2. PMID: 26577123
Routine contralateral breast biopsy: helpful or irrelevant? Experience in 871 patients, 1979-1993.
Cody HS 3rd
Ann Surg 1997 Apr;225(4):370-6. doi: 10.1097/00000658-199704000-00005. PMID: 9114795Free PMC Article

Recent systematic reviews

Bilateral congenital amazia: a case report and systematic review of the literature.
Dreifuss SE, Macisaac ZM, Grunwaldt LJ
J Plast Reconstr Aesthet Surg 2014 Jan;67(1):27-33. Epub 2013 Jul 26 doi: 10.1016/j.bjps.2013.06.048. PMID: 23896162

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