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Abnormal rib ossification

MedGen UID:
868558
•Concept ID:
C4022957
•
Finding
Synonym: Abnormal maturation of rib bones
 
HPO: HP:0012306

Definition

An anomaly of the process of rib bone formation. [from HPO]

Professional guidelines

PubMed

The etiology, clinical features, and treatment options of hemifacial microsomia.
Luo S, Sun H, Bian Q, Liu Z, Wang X
Oral Dis 2023 Sep;29(6):2449-2462. Epub 2023 Mar 13 doi: 10.1111/odi.14508. PMID: 36648381
Prenatal sonographic diagnosis of skeletal dysplasias.
Schramm T, Gloning KP, Minderer S, Daumer-Haas C, Hörtnagel K, Nerlich A, Tutschek B
Ultrasound Obstet Gynecol 2009 Aug;34(2):160-70. doi: 10.1002/uog.6359. PMID: 19548204
Trisomy 21 in newborn infants: chest radiographic diagnosis.
Edwards DK 3rd, Berry CC, Hilton SW
Radiology 1988 May;167(2):317-8. doi: 10.1148/radiology.167.2.2965816. PMID: 2965816

Recent clinical studies

Etiology

Characterization of Chest Wall Toxicity During Long-term Follow Up After Thoracic Stereotactic Body Radiation Therapy.
Chipko C, Ojwang J, Gharai LR, Deng X, Mukhopadhyay N, Weiss E
Pract Radiat Oncol 2019 May;9(3):e338-e346. Epub 2019 Feb 4 doi: 10.1016/j.prro.2019.01.012. PMID: 30731275Free PMC Article
Costochondral grafting in craniofacial microsomia.
Tahiri Y, Chang CS, Tuin J, Paliga JT, Lowe KM, Taylor JA, Bartlett SP
Plast Reconstr Surg 2015 Feb;135(2):530-541. doi: 10.1097/PRS.0000000000000914. PMID: 25626797
Rib cage deformities alter respiratory muscle action and chest wall function in patients with severe osteogenesis imperfecta.
LoMauro A, Pochintesta S, Romei M, D'Angelo MG, Pedotti A, Turconi AC, Aliverti A
PLoS One 2012;7(4):e35965. Epub 2012 Apr 27 doi: 10.1371/journal.pone.0035965. PMID: 22558284Free PMC Article
Distraction osteogenesis of costocartilaginous rib grafts and treatment algorithm for severely hypoplastic mandibles.
Wan DC, Taub PJ, Allam KA, Perry A, Tabit CJ, Kawamoto HK, Bradley JP
Plast Reconstr Surg 2011 May;127(5):2005-2013. doi: 10.1097/PRS.0b013e31820cf4d6. PMID: 21532427
Aetiology of idiopathic scoliosis: current concepts.
Burwell RG
Pediatr Rehabil 2003 Jul-Dec;6(3-4):137-70. doi: 10.1080/13638490310001642757. PMID: 14713582

Diagnosis

Skeletal dysplasias of the fetus and infant: comprehensive review and our experience over a 10-year period.
Ježová M, Pavlovská D, Grochová I, Michenková A, Vlašín P
Cesk Patol 2023 Summer;59(2):68-79. PMID: 37468326
The etiology, clinical features, and treatment options of hemifacial microsomia.
Luo S, Sun H, Bian Q, Liu Z, Wang X
Oral Dis 2023 Sep;29(6):2449-2462. Epub 2023 Mar 13 doi: 10.1111/odi.14508. PMID: 36648381
Pediatric cervical kyphosis in the MRI era (1984-2008) with long-term follow up: literature review.
Menezes AH, Traynelis VC
Childs Nerv Syst 2022 Feb;38(2):361-377. Epub 2021 Nov 22 doi: 10.1007/s00381-021-05409-z. PMID: 34806157
Characterization of Chest Wall Toxicity During Long-term Follow Up After Thoracic Stereotactic Body Radiation Therapy.
Chipko C, Ojwang J, Gharai LR, Deng X, Mukhopadhyay N, Weiss E
Pract Radiat Oncol 2019 May;9(3):e338-e346. Epub 2019 Feb 4 doi: 10.1016/j.prro.2019.01.012. PMID: 30731275Free PMC Article
Costochondral grafting in craniofacial microsomia.
Tahiri Y, Chang CS, Tuin J, Paliga JT, Lowe KM, Taylor JA, Bartlett SP
Plast Reconstr Surg 2015 Feb;135(2):530-541. doi: 10.1097/PRS.0000000000000914. PMID: 25626797

Therapy

Characterization of Chest Wall Toxicity During Long-term Follow Up After Thoracic Stereotactic Body Radiation Therapy.
Chipko C, Ojwang J, Gharai LR, Deng X, Mukhopadhyay N, Weiss E
Pract Radiat Oncol 2019 May;9(3):e338-e346. Epub 2019 Feb 4 doi: 10.1016/j.prro.2019.01.012. PMID: 30731275Free PMC Article
BMPER variants associated with a novel, attenuated subtype of diaphanospondylodysostosis.
Zong Z, Tees S, Miyanji F, Fauth C, Reilly C, Lopez E, Tredwell S, Paul Goldberg Y, Delaney A, Eydoux P, Van Allen M, Lehman A
J Hum Genet 2015 Dec;60(12):743-7. Epub 2015 Oct 15 doi: 10.1038/jhg.2015.116. PMID: 26467725
Supernumerary ribs in developmental toxicity bioassays and in human populations: incidence and biological significance.
Chernoff N, Rogers JM
J Toxicol Environ Health B Crit Rev 2004 Nov-Dec;7(6):437-49. doi: 10.1080/10937400490512447. PMID: 15586878
"Duplicate calcaneus": a rare developmental defect observed in several skeletal dysplasias.
Cormier-Daire V, Savarirayan R, Unger S, Rimoin DL, Lachman RS
Pediatr Radiol 2001 Jan;31(1):38-42. doi: 10.1007/s002470000354. PMID: 11200997
Skeletal malformations associated with esophageal atresia: clinical and experimental studies.
Xia H, Migliazza L, Montedonico S, Rodriguez JI, Diez-Pardo JA, Tovar JA
J Pediatr Surg 1999 Sep;34(9):1385-92. doi: 10.1016/s0022-3468(99)90016-7. PMID: 10507434

Prognosis

Characterization of Chest Wall Toxicity During Long-term Follow Up After Thoracic Stereotactic Body Radiation Therapy.
Chipko C, Ojwang J, Gharai LR, Deng X, Mukhopadhyay N, Weiss E
Pract Radiat Oncol 2019 May;9(3):e338-e346. Epub 2019 Feb 4 doi: 10.1016/j.prro.2019.01.012. PMID: 30731275Free PMC Article
Costochondral grafting in craniofacial microsomia.
Tahiri Y, Chang CS, Tuin J, Paliga JT, Lowe KM, Taylor JA, Bartlett SP
Plast Reconstr Surg 2015 Feb;135(2):530-541. doi: 10.1097/PRS.0000000000000914. PMID: 25626797
Clinical and laboratory features of temporary brittle bone disease.
Paterson CR, Monk EA
J Pediatr Endocrinol Metab 2014 Jan;27(1-2):37-45. doi: 10.1515/jpem-2013-0120. PMID: 23950568
Distraction osteogenesis of costocartilaginous rib grafts and treatment algorithm for severely hypoplastic mandibles.
Wan DC, Taub PJ, Allam KA, Perry A, Tabit CJ, Kawamoto HK, Bradley JP
Plast Reconstr Surg 2011 May;127(5):2005-2013. doi: 10.1097/PRS.0b013e31820cf4d6. PMID: 21532427
Supernumerary ribs in developmental toxicity bioassays and in human populations: incidence and biological significance.
Chernoff N, Rogers JM
J Toxicol Environ Health B Crit Rev 2004 Nov-Dec;7(6):437-49. doi: 10.1080/10937400490512447. PMID: 15586878

Clinical prediction guides

The terminal period findings of late-diagnosed fibrodysplasia ossificans progressiva.
Doğan E, Aydoğmuş H, Elibol C, Aydoğmuş S
Ger Med Sci 2023;21:Doc12. Epub 2023 Jul 11 doi: 10.3205/000326. PMID: 37599859Free PMC Article
Pediatric cervical kyphosis in the MRI era (1984-2008) with long-term follow up: literature review.
Menezes AH, Traynelis VC
Childs Nerv Syst 2022 Feb;38(2):361-377. Epub 2021 Nov 22 doi: 10.1007/s00381-021-05409-z. PMID: 34806157
Rib cage deformities alter respiratory muscle action and chest wall function in patients with severe osteogenesis imperfecta.
LoMauro A, Pochintesta S, Romei M, D'Angelo MG, Pedotti A, Turconi AC, Aliverti A
PLoS One 2012;7(4):e35965. Epub 2012 Apr 27 doi: 10.1371/journal.pone.0035965. PMID: 22558284Free PMC Article
Dysregulation of chondrogenesis in human cleidocranial dysplasia.
Zheng Q, Sebald E, Zhou G, Chen Y, Wilcox W, Lee B, Krakow D
Am J Hum Genet 2005 Aug;77(2):305-12. Epub 2005 Jun 10 doi: 10.1086/432261. PMID: 15952089Free PMC Article
Skeletal abnormalities in the Apert syndrome.
Cohen MM Jr, Kreiborg S
Am J Med Genet 1993 Oct 1;47(5):624-32. doi: 10.1002/ajmg.1320470509. PMID: 8266987

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