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EEG with central focal spike waves

MedGen UID:
868679
•Concept ID:
C4023082
•
Finding
HPO: HP:0012009

Definition

EEG with focal sharp transient waves in the central region, i.e., focal sharp waves of a duration less than 80 msec followed by a slow wave. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEEG with central focal spike waves

Professional guidelines

PubMed

DYNC1H1-related epilepsy: Genotype-phenotype correlation.
Liu W, Cheng M, Zhu Y, Chen Y, Yang Y, Chen H, Niu X, Tian X, Yang X, Zhang Y
Dev Med Child Neurol 2023 Apr;65(4):534-543. Epub 2022 Sep 29 doi: 10.1111/dmcn.15414. PMID: 36175372
EEG in the differential diagnosis between Alzheimer's disease and vascular dementia.
Erkinjuntti T, Larsen T, Sulkava R, Ketonen L, Laaksonen R, Palo J
Acta Neurol Scand 1988 Jan;77(1):36-43. doi: 10.1111/j.1600-0404.1988.tb06971.x. PMID: 3354310

Recent clinical studies

Etiology

Specific electroencephalogram features in the very early phases of sporadic Creutzfeldt-Jakob disease.
Matsubayashi T, Akaza M, Hayashi Y, Hamaguchi T, Satoh K, Kosami K, Ae R, Kitamoto T, Yamada M, Shimohata T, Yokota T, Sanjo N
J Neurol Sci 2022 Jun 15;437:120265. Epub 2022 Apr 18 doi: 10.1016/j.jns.2022.120265. PMID: 35472604
Pharmacological monitoring of antiepileptic drugs in epilepsy patients on haemodialysis.
Araki K, Nakamura T, Takeuchi Y, Morozumi S, Horie K, Kobayashi Y, Kawakami O, Sobue F, Ueda T, Hamada K, Ando T, Inoue Y, Yasui K, Morozumi K, Maruyama S, Katsuno M
Epileptic Disord 2020 Feb 1;22(1):90-102. doi: 10.1684/epd.2020.1139. PMID: 32031531
Idiopathic focal epilepsies: the "lost tribe".
Pal DK, Ferrie C, Addis L, Akiyama T, Capovilla G, Caraballo R, de Saint-Martin A, Fejerman N, Guerrini R, Hamandi K, Helbig I, Ioannides AA, Kobayashi K, Lal D, Lesca G, Muhle H, Neubauer BA, Pisano T, Rudolf G, Seegmuller C, Shibata T, Smith A, Striano P, Strug LJ, Szepetowski P, Valeta T, Yoshinaga H, Koutroumanidis M
Epileptic Disord 2016 Sep 1;18(3):252-88. doi: 10.1684/epd.2016.0839. PMID: 27435520
Panayiotopoulos syndrome and symptomatic occipital lobe epilepsy of childhood: a clinical and EEG study.
Tata G, Guveli BT, Dortcan N, Cokar O, Kurucu H, Demirbilek V, Dervent A
Epileptic Disord 2014 Jun;16(2):197-202. doi: 10.1684/epd.2014.0652. PMID: 24777033
Unusual EEG patterns.
Westmoreland BF, Klass DW
J Clin Neurophysiol 1990 Apr;7(2):209-28. doi: 10.1097/00004691-199004000-00005. PMID: 2187021

Diagnosis

DYNC1H1-related epilepsy: Genotype-phenotype correlation.
Liu W, Cheng M, Zhu Y, Chen Y, Yang Y, Chen H, Niu X, Tian X, Yang X, Zhang Y
Dev Med Child Neurol 2023 Apr;65(4):534-543. Epub 2022 Sep 29 doi: 10.1111/dmcn.15414. PMID: 36175372
Specific electroencephalogram features in the very early phases of sporadic Creutzfeldt-Jakob disease.
Matsubayashi T, Akaza M, Hayashi Y, Hamaguchi T, Satoh K, Kosami K, Ae R, Kitamoto T, Yamada M, Shimohata T, Yokota T, Sanjo N
J Neurol Sci 2022 Jun 15;437:120265. Epub 2022 Apr 18 doi: 10.1016/j.jns.2022.120265. PMID: 35472604
Two cases of DYNC1H1 mutations with intractable epilepsy.
Matsumoto A, Kojima K, Miya F, Miyauchi A, Watanabe K, Iwamoto S, Kawai K, Kato M, Takahashi Y, Yamagata T
Brain Dev 2021 Sep;43(8):857-862. Epub 2021 Jun 3 doi: 10.1016/j.braindev.2021.05.005. PMID: 34092403
Epileptic syndromes in infancy and childhood.
Nabbout R, Dulac O
Curr Opin Neurol 2008 Apr;21(2):161-6. doi: 10.1097/WCO.0b013e3282f7007e. PMID: 18317274
The EEG findings in extratemporal seizures.
Westmoreland BF
Epilepsia 1998;39 Suppl 4:S1-8. doi: 10.1111/j.1528-1157.1998.tb05121.x. PMID: 9637588

Therapy

Two cases of DYNC1H1 mutations with intractable epilepsy.
Matsumoto A, Kojima K, Miya F, Miyauchi A, Watanabe K, Iwamoto S, Kawai K, Kato M, Takahashi Y, Yamagata T
Brain Dev 2021 Sep;43(8):857-862. Epub 2021 Jun 3 doi: 10.1016/j.braindev.2021.05.005. PMID: 34092403
Idiopathic focal epilepsies: the "lost tribe".
Pal DK, Ferrie C, Addis L, Akiyama T, Capovilla G, Caraballo R, de Saint-Martin A, Fejerman N, Guerrini R, Hamandi K, Helbig I, Ioannides AA, Kobayashi K, Lal D, Lesca G, Muhle H, Neubauer BA, Pisano T, Rudolf G, Seegmuller C, Shibata T, Smith A, Striano P, Strug LJ, Szepetowski P, Valeta T, Yoshinaga H, Koutroumanidis M
Epileptic Disord 2016 Sep 1;18(3):252-88. doi: 10.1684/epd.2016.0839. PMID: 27435520
Early postnatal EEG features of perinatal arterial ischaemic stroke with seizures.
Low E, Mathieson SR, Stevenson NJ, Livingstone V, Ryan CA, Bogue CO, Rennie JM, Boylan GB
PLoS One 2014;9(7):e100973. Epub 2014 Jul 22 doi: 10.1371/journal.pone.0100973. PMID: 25051161Free PMC Article
Benign infantile focal epilepsy with midline spikes and waves during sleep: a new epileptic syndrome or a variant of benign focal epilepsy?
Flesler S, Sakr D, Cersósimo R, Caraballo R
Epileptic Disord 2010 Sep;12(3):205-11. doi: 10.1684/epd.2010.0320. PMID: 20822975
Comparison of epileptic and nonepileptic cases with centrotemporal spikes in view of clinical findings and electroencephalographic characteristics.
Tombul T, Anlar O, Caksen H
Int J Neurosci 2006 Mar;116(3):299-313. doi: 10.1080/00207450500403272. PMID: 16484056

Prognosis

A case report of anti-GAD65 antibody-positive autoimmune encephalitis in children associated with autoimmune polyendocrine syndrome type-II and literature review.
Sapana T, Li W, Tian F, Yan W, Dou B, Hua S, Zhuo Z
Front Immunol 2023;14:1274672. Epub 2023 Nov 22 doi: 10.3389/fimmu.2023.1274672. PMID: 38077387Free PMC Article
Flexible resonance in prefrontal networks with strong feedback inhibition.
Sherfey JS, Ardid S, Hass J, Hasselmo ME, Kopell NJ
PLoS Comput Biol 2018 Aug;14(8):e1006357. Epub 2018 Aug 9 doi: 10.1371/journal.pcbi.1006357. PMID: 30091975Free PMC Article
Idiopathic focal epilepsies: the "lost tribe".
Pal DK, Ferrie C, Addis L, Akiyama T, Capovilla G, Caraballo R, de Saint-Martin A, Fejerman N, Guerrini R, Hamandi K, Helbig I, Ioannides AA, Kobayashi K, Lal D, Lesca G, Muhle H, Neubauer BA, Pisano T, Rudolf G, Seegmuller C, Shibata T, Smith A, Striano P, Strug LJ, Szepetowski P, Valeta T, Yoshinaga H, Koutroumanidis M
Epileptic Disord 2016 Sep 1;18(3):252-88. doi: 10.1684/epd.2016.0839. PMID: 27435520
Long-term prognosis of patients with Ehlers-Danlos syndrome and epilepsy.
Verrotti A, Spartà MV, Monacelli D, Porto R, Castagnino M, Russo Raucci A, Compagno F, Viglio S, Foiadelli T, Nicita F, Grosso S, Spalice A, Chiarelli F, Marseglia G, Savasta S
Epilepsia 2014 Aug;55(8):1213-9. Epub 2014 Jun 25 doi: 10.1111/epi.12699. PMID: 24965265
Seizures and EEG pattern in Kabuki syndrome.
Lodi M, Chifari R, Parazzini C, Viri M, Beccaria F, Lorenzetti ME, Meloni M, Capovilla G, Romeo A
Brain Dev 2010 Nov;32(10):829-34. Epub 2010 Jan 12 doi: 10.1016/j.braindev.2009.12.006. PMID: 20061104

Clinical prediction guides

Flexible resonance in prefrontal networks with strong feedback inhibition.
Sherfey JS, Ardid S, Hass J, Hasselmo ME, Kopell NJ
PLoS Comput Biol 2018 Aug;14(8):e1006357. Epub 2018 Aug 9 doi: 10.1371/journal.pcbi.1006357. PMID: 30091975Free PMC Article
Idiopathic focal epilepsies: the "lost tribe".
Pal DK, Ferrie C, Addis L, Akiyama T, Capovilla G, Caraballo R, de Saint-Martin A, Fejerman N, Guerrini R, Hamandi K, Helbig I, Ioannides AA, Kobayashi K, Lal D, Lesca G, Muhle H, Neubauer BA, Pisano T, Rudolf G, Seegmuller C, Shibata T, Smith A, Striano P, Strug LJ, Szepetowski P, Valeta T, Yoshinaga H, Koutroumanidis M
Epileptic Disord 2016 Sep 1;18(3):252-88. doi: 10.1684/epd.2016.0839. PMID: 27435520
Early postnatal EEG features of perinatal arterial ischaemic stroke with seizures.
Low E, Mathieson SR, Stevenson NJ, Livingstone V, Ryan CA, Bogue CO, Rennie JM, Boylan GB
PLoS One 2014;9(7):e100973. Epub 2014 Jul 22 doi: 10.1371/journal.pone.0100973. PMID: 25051161Free PMC Article
Benign infantile focal epilepsy with midline spikes and waves during sleep: a new epileptic syndrome or a variant of benign focal epilepsy?
Flesler S, Sakr D, Cersósimo R, Caraballo R
Epileptic Disord 2010 Sep;12(3):205-11. doi: 10.1684/epd.2010.0320. PMID: 20822975
Comparison of epileptic and nonepileptic cases with centrotemporal spikes in view of clinical findings and electroencephalographic characteristics.
Tombul T, Anlar O, Caksen H
Int J Neurosci 2006 Mar;116(3):299-313. doi: 10.1080/00207450500403272. PMID: 16484056

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