U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Left aortic arch with cervical origin of the right subclavian artery

MedGen UID:
868870
•Concept ID:
C4023281
•
Anatomical Abnormality
HPO: HP:0011591

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLeft aortic arch with cervical origin of the right subclavian artery

Conditions with this feature

Cardiac valvular defect, developmental
MedGen UID:
1823949
•Concept ID:
C5774175
•
Disease or Syndrome
Cardiac valvular dysplasia-1 (CVDP1) is characterized by congenital malformations of the pulmonic, tricuspid, and mitral valves. Structural cardiac defects, including atrial and ventricular septal defects, single left ventricle, and hypoplastic right ventricle have also been observed in affected individuals (Ta-Shma et al., 2017). Genetic Heterogeneity of Cardiac Valvular Dysplasia CVDP2 (620067) is caused by mutation in the ADAMTS19 gene (607513) on chromosome 5q23.
See: Condition Record
Cardiac valvular defect, developmental

Professional guidelines

PubMed

Prenatal Ultrasonic Diagnosis and Prognostic Analysis of Isolated Left Subclavian Artery (ILSCA) and Left Brachiocephalic Trunk (ILBCT) Malformation.
Li Y, Zhang X, Yan Y, Pei Q
Pediatr Cardiol 2018 Dec;39(8):1650-1655. Epub 2018 Aug 27 doi: 10.1007/s00246-018-1945-1. PMID: 30167747

Recent clinical studies

Etiology

Mapping of Anatomic Variants of the Proximal Vertebral Artery in Relation to Embryology.
Bueno HF, Nimchinsky EA
AJNR Am J Neuroradiol 2023 Aug;44(8):943-950. Epub 2023 Jul 27 doi: 10.3174/ajnr.A7942. PMID: 37500289Free PMC Article
Anatomical variation in the branching pattern of the aortic arch: a literature review.
Murray A, Meguid EA
Ir J Med Sci 2023 Aug;192(4):1807-1817. Epub 2022 Oct 22 doi: 10.1007/s11845-022-03196-3. PMID: 36272028Free PMC Article
Multidetector computed tomography evaluation of origin, V2 segment variations and morphology of vertebral artery.
Tasdemir R, Cihan OF
Folia Morphol (Warsz) 2023;82(2):274-281. Epub 2022 Mar 29 doi: 10.5603/FM.a2022.0030. PMID: 35347695
Variations of the extracranial segment of vertebral artery as a bleeding risk factor.
Yaprak F, Ozer MA, Govsa F, Eraslan C
Surg Radiol Anat 2021 Oct;43(10):1735-1743. Epub 2021 Apr 22 doi: 10.1007/s00276-021-02748-z. PMID: 33890143
Aberrant Origin of Vertebral Artery and its Clinical Implications.
Yuan SM
Braz J Cardiovasc Surg 2016 Feb;31(1):52-9. doi: 10.5935/1678-9741.20150071. PMID: 27074275Free PMC Article

Diagnosis

Multidetector computed tomography evaluation of origin, V2 segment variations and morphology of vertebral artery.
Tasdemir R, Cihan OF
Folia Morphol (Warsz) 2023;82(2):274-281. Epub 2022 Mar 29 doi: 10.5603/FM.a2022.0030. PMID: 35347695
Prenatal Ultrasonic Diagnosis and Prognostic Analysis of Isolated Left Subclavian Artery (ILSCA) and Left Brachiocephalic Trunk (ILBCT) Malformation.
Li Y, Zhang X, Yan Y, Pei Q
Pediatr Cardiol 2018 Dec;39(8):1650-1655. Epub 2018 Aug 27 doi: 10.1007/s00246-018-1945-1. PMID: 30167747
A cadaveric study of aortic arch variation in an Irish population.
O'Malley AM, El Kininy WH, Debebe H, Burukan AB, Davy SW
Ir J Med Sci 2018 Aug;187(3):853-858. Epub 2017 Dec 29 doi: 10.1007/s11845-017-1729-2. PMID: 29288397
Hybrid Treatment of the Aberrant Right Subclavian Artery (Arteria Lusoria): Feasibility Study on 180 Angio-CTs.
Settembre N, Saba C, Bouziane Z, Jeannon F, Mandry D, Malikov S
Ann Vasc Surg 2017 Oct;44:229-233. Epub 2017 May 9 doi: 10.1016/j.avsg.2017.03.172. PMID: 28495534
Hybrid repair of Kommerell diverticulum.
Idrees J, Keshavamurthy S, Subramanian S, Clair DG, Svensson LG, Roselli EE
J Thorac Cardiovasc Surg 2014 Mar;147(3):973-6. Epub 2013 Mar 25 doi: 10.1016/j.jtcvs.2013.02.063. PMID: 23535153

Therapy

A Phylogenetic and Ontogenetic Perspective of the Unique Accumulation of Arterial Variations in One Human Anatomic Specimen.
Pretterklieber B, Pretterklieber ML
Medicina (Kaunas) 2020 Sep 4;56(9) doi: 10.3390/medicina56090449. PMID: 32899761Free PMC Article
Variability of the vertebral artery origin and transverse foramen entrance level - CT angiographic study.
Vujmilović S, Spasojević G, Vujnović S, Malobabić S, Vujković Z
Folia Morphol (Warsz) 2018;77(4):687-692. Epub 2018 Apr 13 doi: 10.5603/FM.a2018.0036. PMID: 29651795
Hybrid repair of Kommerell diverticulum.
Idrees J, Keshavamurthy S, Subramanian S, Clair DG, Svensson LG, Roselli EE
J Thorac Cardiovasc Surg 2014 Mar;147(3):973-6. Epub 2013 Mar 25 doi: 10.1016/j.jtcvs.2013.02.063. PMID: 23535153
The applicability of chimney grafts in the aortic arch.
Sugiura K, Sonesson B, Akesson M, Björses K, Holst J, Malina M
J Cardiovasc Surg (Torino) 2009 Aug;50(4):475-81. PMID: 19734832
Does recurrent laryngeal nerve anatomy condition the choice of the side for approaching the anterior cervical spine?
Miscusi M, Bellitti A, Peschillo S, Polli FM, Missori P, Delfini R
J Neurosurg Sci 2007 Jun;51(2):61-4. PMID: 17571036

Prognosis

Mapping of Anatomic Variants of the Proximal Vertebral Artery in Relation to Embryology.
Bueno HF, Nimchinsky EA
AJNR Am J Neuroradiol 2023 Aug;44(8):943-950. Epub 2023 Jul 27 doi: 10.3174/ajnr.A7942. PMID: 37500289Free PMC Article
The Brachiocephalic Trunk Variant Origin and High-Riding Course: Two Cadaveric Cases.
Tsakotos G, Demesticha T, Karampelias V, Natsis K, Protogerou V, Schizas D, Chatziandreou I, Kostare G, Piagkou M
Acta Med Acad 2023 Apr;52(1):51-55. doi: 10.5644/ama2006-124.402. PMID: 37326398Free PMC Article
Variations of the extracranial segment of vertebral artery as a bleeding risk factor.
Yaprak F, Ozer MA, Govsa F, Eraslan C
Surg Radiol Anat 2021 Oct;43(10):1735-1743. Epub 2021 Apr 22 doi: 10.1007/s00276-021-02748-z. PMID: 33890143
A Phylogenetic and Ontogenetic Perspective of the Unique Accumulation of Arterial Variations in One Human Anatomic Specimen.
Pretterklieber B, Pretterklieber ML
Medicina (Kaunas) 2020 Sep 4;56(9) doi: 10.3390/medicina56090449. PMID: 32899761Free PMC Article
Aberrant Origin of Vertebral Artery and its Clinical Implications.
Yuan SM
Braz J Cardiovasc Surg 2016 Feb;31(1):52-9. doi: 10.5935/1678-9741.20150071. PMID: 27074275Free PMC Article

Clinical prediction guides

Mapping of Anatomic Variants of the Proximal Vertebral Artery in Relation to Embryology.
Bueno HF, Nimchinsky EA
AJNR Am J Neuroradiol 2023 Aug;44(8):943-950. Epub 2023 Jul 27 doi: 10.3174/ajnr.A7942. PMID: 37500289Free PMC Article
Multidetector computed tomography evaluation of origin, V2 segment variations and morphology of vertebral artery.
Tasdemir R, Cihan OF
Folia Morphol (Warsz) 2023;82(2):274-281. Epub 2022 Mar 29 doi: 10.5603/FM.a2022.0030. PMID: 35347695
Prenatal Ultrasonic Diagnosis and Prognostic Analysis of Isolated Left Subclavian Artery (ILSCA) and Left Brachiocephalic Trunk (ILBCT) Malformation.
Li Y, Zhang X, Yan Y, Pei Q
Pediatr Cardiol 2018 Dec;39(8):1650-1655. Epub 2018 Aug 27 doi: 10.1007/s00246-018-1945-1. PMID: 30167747
A cadaveric study of aortic arch variation in an Irish population.
O'Malley AM, El Kininy WH, Debebe H, Burukan AB, Davy SW
Ir J Med Sci 2018 Aug;187(3):853-858. Epub 2017 Dec 29 doi: 10.1007/s11845-017-1729-2. PMID: 29288397
Aberrant Origin of Vertebral Artery and its Clinical Implications.
Yuan SM
Braz J Cardiovasc Surg 2016 Feb;31(1):52-9. doi: 10.5935/1678-9741.20150071. PMID: 27074275Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...