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Metopic depression

MedGen UID:
869036
•Concept ID:
C4023454
•
Anatomical Abnormality
Synonyms: Depression of frontal cranial suture; Depression of metopic cranial suture; Frontal suture depression
 
HPO: HP:0011223

Definition

Linear vertical groove in the midline of the forehead, extending from hairline to glabella. [from HPO]

Recent clinical studies

Etiology

"Validation of Artificial Intelligence Severity Assessment in Metopic Craniosynostosis".
Junn A, Dinis J, Hauc SC, Bruce MK, Park KE, Tao W, Christensen C, Whitaker R, Goldstein JA, Alperovich M
Cleft Palate Craniofac J 2023 Mar;60(3):274-279. Epub 2021 Nov 17 doi: 10.1177/10556656211061021. PMID: 34787505Free PMC Article
Appearance or attitude: what matters to craniosynostosis patients? Association of self-esteem, depressive symptoms, and facial aesthetics in patients with sagittal and metopic synostosis.
Svalina A, Heikura E, Savolainen T, Serlo W, Sinikumpu JJ, Silvola AS, Salokorpi N
Childs Nerv Syst 2022 Oct;38(10):1929-1936. Epub 2022 Jun 23 doi: 10.1007/s00381-022-05587-4. PMID: 35732900Free PMC Article
Cognitive, behavioral and psychological functioning of children and adults with conservatively managed metopic synostosis.
Osborn AJ, Roberts RM, Mathias JL, Anderson PJ, Flapper WJ
Child Neuropsychol 2021 Feb;27(2):190-208. Epub 2020 Sep 8 doi: 10.1080/09297049.2020.1817356. PMID: 32900282
Surgical treatment of trigonocephaly: technique and long-term results in 48 cases.
Ozlen F, Kafadar AM, Abuzayed B, Ulu MO, Isler C, Dashti R, Erdincler P
J Neurosurg Pediatr 2011 Mar;7(3):300-10. doi: 10.3171/2010.12.PEDS10359. PMID: 21361772
Metopic suture in fetuses with Apert syndrome at 22-27 weeks of gestation.
Faro C, Chaoui R, Wegrzyn P, Levaillant JM, Benoit B, Nicolaides KH
Ultrasound Obstet Gynecol 2006 Jan;27(1):28-33. doi: 10.1002/uog.2648. PMID: 16317802

Diagnosis

"Validation of Artificial Intelligence Severity Assessment in Metopic Craniosynostosis".
Junn A, Dinis J, Hauc SC, Bruce MK, Park KE, Tao W, Christensen C, Whitaker R, Goldstein JA, Alperovich M
Cleft Palate Craniofac J 2023 Mar;60(3):274-279. Epub 2021 Nov 17 doi: 10.1177/10556656211061021. PMID: 34787505Free PMC Article
Cognitive, behavioral and psychological functioning of children and adults with conservatively managed metopic synostosis.
Osborn AJ, Roberts RM, Mathias JL, Anderson PJ, Flapper WJ
Child Neuropsychol 2021 Feb;27(2):190-208. Epub 2020 Sep 8 doi: 10.1080/09297049.2020.1817356. PMID: 32900282
Cleidocranial Dysplasia: Management of the Multiple Craniofacial and Skeletal Anomalies.
Jirapinyo C, Deraje V, Huang G, Gue S, Anderson PJ, Moore MH
J Craniofac Surg 2020 Jun;31(4):908-911. doi: 10.1097/SCS.0000000000006306. PMID: 32224772
Heterozygous mutations in ERF cause syndromic craniosynostosis with multiple suture involvement.
Chaudhry A, Sabatini P, Han L, Ray PN, Forrest C, Bowdin S
Am J Med Genet A 2015 Nov;167A(11):2544-7. Epub 2015 Jun 22 doi: 10.1002/ajmg.a.37218. PMID: 26097063
Surgical treatment of trigonocephaly: technique and long-term results in 48 cases.
Ozlen F, Kafadar AM, Abuzayed B, Ulu MO, Isler C, Dashti R, Erdincler P
J Neurosurg Pediatr 2011 Mar;7(3):300-10. doi: 10.3171/2010.12.PEDS10359. PMID: 21361772

Therapy

Correction of depressed forehead with BoneSource in cleidocranial dysplasia.
Kang N, Kim SZ, Jung SN
J Craniofac Surg 2009 Mar;20(2):564-6. doi: 10.1097/SCS.0b013e31819ba361. PMID: 19305258
The hourglass facial deformity as a consequence of orbital irradiation for bilateral retinoblastoma.
Yue NC, Benson ML
Pediatr Radiol 1996;26(6):421-3. doi: 10.1007/BF01387319. PMID: 8657482

Prognosis

Endocortical plating of the bandeau during fronto-orbital advancement provides safe and effective osseous stabilization.
Sauerhammer TM, Seruya M, Basci D, Rogers GF, Keating RF, Boyajian MJ, Oh AK
J Craniofac Surg 2014 Jul;25(4):1341-5. doi: 10.1097/SCS.0000000000000810. PMID: 24902106
Surgical treatment of trigonocephaly: technique and long-term results in 48 cases.
Ozlen F, Kafadar AM, Abuzayed B, Ulu MO, Isler C, Dashti R, Erdincler P
J Neurosurg Pediatr 2011 Mar;7(3):300-10. doi: 10.3171/2010.12.PEDS10359. PMID: 21361772
Correction of depressed forehead with BoneSource in cleidocranial dysplasia.
Kang N, Kim SZ, Jung SN
J Craniofac Surg 2009 Mar;20(2):564-6. doi: 10.1097/SCS.0b013e31819ba361. PMID: 19305258
Familial occurrence of Summitt syndrome or a variant example of Carpenter syndrome?
Pierquin G, Seligmann R, Van Regemorter N
Genet Couns 1992;3(2):101-5. PMID: 1642806

Clinical prediction guides

"Validation of Artificial Intelligence Severity Assessment in Metopic Craniosynostosis".
Junn A, Dinis J, Hauc SC, Bruce MK, Park KE, Tao W, Christensen C, Whitaker R, Goldstein JA, Alperovich M
Cleft Palate Craniofac J 2023 Mar;60(3):274-279. Epub 2021 Nov 17 doi: 10.1177/10556656211061021. PMID: 34787505Free PMC Article
Surgical treatment of trigonocephaly: technique and long-term results in 48 cases.
Ozlen F, Kafadar AM, Abuzayed B, Ulu MO, Isler C, Dashti R, Erdincler P
J Neurosurg Pediatr 2011 Mar;7(3):300-10. doi: 10.3171/2010.12.PEDS10359. PMID: 21361772
Correction of depressed forehead with BoneSource in cleidocranial dysplasia.
Kang N, Kim SZ, Jung SN
J Craniofac Surg 2009 Mar;20(2):564-6. doi: 10.1097/SCS.0b013e31819ba361. PMID: 19305258

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