U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal nasal bone morphology

MedGen UID:
869215
•Concept ID:
C4023637
•
Anatomical Abnormality
Synonyms: Abnormality of the nasal bone; Anomaly of the nasal bones; Deformity of the nasal bones; Malformation of the nasal bones
 
HPO: HP:0010939

Definition

An abnormality of the nasal bone, comprising the left nasal bone and the right nasal bone. [from HPO]

Professional guidelines

PubMed

ALX-Related Frontonasal Dysplasias: Clinical Characteristics and Surgical Management.
Vargel I, Canter HI, Kucukguven A, Aydin A, Ozgur F
Cleft Palate Craniofac J 2022 May;59(5):637-643. Epub 2021 Jun 8 doi: 10.1177/10556656211019621. PMID: 34098755
Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of isolated soft ultrasound markers for aneuploidy in the second trimester: (Replaces Consults #10, Single umbilical artery, October 2010; #16, Isolated echogenic bowel diagnosed on second-trimester ultrasound, August 2011; #17, Evaluation and management of isolated renal pelviectasis on second-trimester ultrasound, December 2011; #25, Isolated fetal choroid plexus cysts, April 2013; #27, Isolated echogenic intracardiac focus, August 2013).
Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.org, Prabhu M, Kuller JA, Biggio JR
Am J Obstet Gynecol 2021 Oct;225(4):B2-B15. Epub 2021 Jun 23 doi: 10.1016/j.ajog.2021.06.079. PMID: 34171388
Management of the alveolar cleft.
Santiago PE, Schuster LA, Levy-Bercowski D
Clin Plast Surg 2014 Apr;41(2):219-32. doi: 10.1016/j.cps.2014.01.001. PMID: 24607190

Recent clinical studies

Etiology

Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of isolated soft ultrasound markers for aneuploidy in the second trimester: (Replaces Consults #10, Single umbilical artery, October 2010; #16, Isolated echogenic bowel diagnosed on second-trimester ultrasound, August 2011; #17, Evaluation and management of isolated renal pelviectasis on second-trimester ultrasound, December 2011; #25, Isolated fetal choroid plexus cysts, April 2013; #27, Isolated echogenic intracardiac focus, August 2013).
Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.org, Prabhu M, Kuller JA, Biggio JR
Am J Obstet Gynecol 2021 Oct;225(4):B2-B15. Epub 2021 Jun 23 doi: 10.1016/j.ajog.2021.06.079. PMID: 34171388
Revisiting absent nasal bone in the second trimester.
Singh C, Thakur S, Arora N, Khurana D
J Clin Ultrasound 2021 Jan;49(1):3-7. Epub 2020 Jun 10 doi: 10.1002/jcu.22877. PMID: 32521052
Cerebro-oculo-facio-skeletal syndrome.
Suzumura H, Arisaka O
Adv Exp Med Biol 2010;685:210-4. doi: 10.1007/978-1-4419-6448-9_19. PMID: 20687508
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Midface anomalies in children.
Lowe LH, Booth TN, Joglar JM, Rollins NK
Radiographics 2000 Jul-Aug;20(4):907-22; quiz 1106-7, 1112. doi: 10.1148/radiographics.20.4.g00jl07907. PMID: 10903683

Diagnosis

Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of isolated soft ultrasound markers for aneuploidy in the second trimester: (Replaces Consults #10, Single umbilical artery, October 2010; #16, Isolated echogenic bowel diagnosed on second-trimester ultrasound, August 2011; #17, Evaluation and management of isolated renal pelviectasis on second-trimester ultrasound, December 2011; #25, Isolated fetal choroid plexus cysts, April 2013; #27, Isolated echogenic intracardiac focus, August 2013).
Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.org, Prabhu M, Kuller JA, Biggio JR
Am J Obstet Gynecol 2021 Oct;225(4):B2-B15. Epub 2021 Jun 23 doi: 10.1016/j.ajog.2021.06.079. PMID: 34171388
Absent nasal bone.
Society for Maternal-Fetal Medicine, Benacerraf BR, Bromley B, Jelin AC
Am J Obstet Gynecol 2019 Nov;221(5):B6-B7. doi: 10.1016/j.ajog.2019.08.049. PMID: 31679594
Pyriform aperture enlargement in all aspects.
Esen E, Bayar Muluk N, Altintoprak N, Ipci K, Cingi C
J Laryngol Otol 2017 Jun;131(6):476-479. Epub 2017 Feb 27 doi: 10.1017/S0022215117000391. PMID: 28238296
Developmental maxillofacial anomalies.
Baxter DJ, Shroff MM
Semin Ultrasound CT MR 2011 Dec;32(6):555-68. doi: 10.1053/j.sult.2011.06.004. PMID: 22108218
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938

Therapy

Correlation between alveolar cleft morphology and the outcome of secondary alveolar bone grafting for unilateral cleft lip and palate.
Yu X, Huang Y, Li W
BMC Oral Health 2022 Jun 22;22(1):251. doi: 10.1186/s12903-022-02265-4. PMID: 35733126Free PMC Article
Olfactory cleft dilatation.
Jankowski R, Nguyen DT, Gallet P, Rumeau C
Eur Ann Otorhinolaryngol Head Neck Dis 2018 Dec;135(6):437-441. Epub 2018 Jun 20 doi: 10.1016/j.anorl.2018.05.008. PMID: 29934261
Osseous-Cartilaginous Spreader Graft and Nasal Framework Reconstruction.
Ors S
Aesthetic Plast Surg 2017 Oct;41(5):1155-1163. Epub 2017 Jun 21 doi: 10.1007/s00266-017-0916-x. PMID: 28639070
Asymmetric nasal tip.
Stephan S, Wang TD
Facial Plast Surg 2012 Apr;28(2):177-86. Epub 2012 May 6 doi: 10.1055/s-0032-1309297. PMID: 22562567
Nasolabial aesthetics.
Mitchell C, Oeltjen J, Panthaki Z, Thaller SR
J Craniofac Surg 2007 Jul;18(4):756-65. doi: 10.1097/scs.0b013e3180684360. PMID: 17667661

Prognosis

Absent nasal bone.
Society for Maternal-Fetal Medicine, Benacerraf BR, Bromley B, Jelin AC
Am J Obstet Gynecol 2019 Nov;221(5):B6-B7. doi: 10.1016/j.ajog.2019.08.049. PMID: 31679594
Medial Osteoectomy as a Routine Procedure in Rhinoplasty: Six-Year Experience with an Innovative Technique.
Lykoudis EG, Peristeri DV, Lykoudis GE, Oikonomou GA
Aesthetic Plast Surg 2018 Feb;42(1):256-263. Epub 2017 Aug 4 doi: 10.1007/s00266-017-0954-4. PMID: 28779410
Pyriform aperture enlargement in all aspects.
Esen E, Bayar Muluk N, Altintoprak N, Ipci K, Cingi C
J Laryngol Otol 2017 Jun;131(6):476-479. Epub 2017 Feb 27 doi: 10.1017/S0022215117000391. PMID: 28238296
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Nasal encephaloceles.
Hoving EW
Childs Nerv Syst 2000 Nov;16(10-11):702-6. doi: 10.1007/s003810000339. PMID: 11151720

Clinical prediction guides

Revisiting absent nasal bone in the second trimester.
Singh C, Thakur S, Arora N, Khurana D
J Clin Ultrasound 2021 Jan;49(1):3-7. Epub 2020 Jun 10 doi: 10.1002/jcu.22877. PMID: 32521052
Cranial Pair 0: The Nervus Terminalis.
Peña-Melián Á, Cabello-de la Rosa JP, Gallardo-Alcañiz MJ, Vaamonde-Gamo J, Relea-Calatayud F, González-López L, Villanueva-Anguita P, Flores-Cuadrado A, Saiz-Sánchez D, Martínez-Marcos A
Anat Rec (Hoboken) 2019 Mar;302(3):394-404. Epub 2018 May 17 doi: 10.1002/ar.23826. PMID: 29663690
Facial clefts and facial dysplasia: revisiting the classification.
Mazzola RF, Mazzola IC
J Craniofac Surg 2014 Jan;25(1):26-34. doi: 10.1097/SCS.0b013e3182a2ea94. PMID: 24406554
Anterior plagiocephaly: epidemiology, clinical findings,diagnosis, and classification. A review.
Di Rocco C, Paternoster G, Caldarelli M, Massimi L, Tamburrini G
Childs Nerv Syst 2012 Sep;28(9):1413-22. Epub 2012 Aug 8 doi: 10.1007/s00381-012-1845-2. PMID: 22872257
First trimester prenatal diagnosis.
Bahado-Singh RO, Cheng CS
Curr Opin Obstet Gynecol 2004 Apr;16(2):177-81. doi: 10.1097/00001703-200404000-00014. PMID: 15017349

Recent systematic reviews

Anatomical variations and abnormalities of the maxillary region and clinical implications: A systematic review and metaanalysis.
Valenzuela-Fuenzalida JJ, Baez-Flores B, Sepúlveda RÁ, Medina CM, Pérez R, López E, Sanchis J, Orellana Donoso M, Silva JL, Rodriguez MC, Iwanaga J
Medicine (Baltimore) 2023 Sep 22;102(38):e34510. doi: 10.1097/MD.0000000000034510. PMID: 37747000Free PMC Article
Pyriform Aperture Enlargement for Internal Nasal Valve Obstruction in Adults: Systematic Review and Surgical Classification.
Hajem H, Botter C, Al Omani M, Sounthakith V, de Bressieux E, Benkhatar H
Otolaryngol Head Neck Surg 2021 Nov;165(5):745-750. Epub 2021 Mar 2 doi: 10.1177/0194599821994739. PMID: 33648407
Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients.
Kloukos D, Fudalej P, Sequeira-Byron P, Katsaros C
Cochrane Database Syst Rev 2018 Aug 10;8(8):CD010403. doi: 10.1002/14651858.CD010403.pub3. PMID: 30095853Free PMC Article
Systematic review and meta-analysis of performance of second-trimester nasal bone assessment in detection of fetuses with Down syndrome.
Moreno-Cid M, Rubio-Lorente A, Rodríguez MJ, Bueno-Pacheco G, Tenías JM, Román-Ortiz C, Arias Á
Ultrasound Obstet Gynecol 2014 Mar;43(3):247-53. doi: 10.1002/uog.13228. PMID: 24151178
Management of the nasal dorsum in rhinoplasty: a systematic review of the literature regarding technique, outcomes, and complications.
Lee MR, Unger JG, Rohrich RJ
Plast Reconstr Surg 2011 Nov;128(5):538e-550e. doi: 10.1097/PRS.0b013e31822b6a82. PMID: 22030516

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...