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Patchy changes of bone mineral density

MedGen UID:
869328
•Concept ID:
C4023754
•
Finding
HPO: HP:0010658

Definition

Patchy (irregular) changes in bone mineral density. These changes can either be patchy reduction or increase of mineral density as seen on x-rays. Depending on the pathomechanism and the underlying disease, these changes can either appear solely as reduction or increase or as a combination of both (patches of bone showing an increased density while others are affected by reduction of mineral density). [from HPO]

Recent clinical studies

Etiology

The bone-vacuum cementing technique for the fixation of the stem in total hip arthroplasty.
Pitto RP, Kessler M, Schikora N, di Muria GV
Chir Organi Mov 2001 Apr-Jun;86(2):99-110. PMID: 12025052
Clinical outcome and quantitative evaluation of periprosthetic bone-remodeling of an uncemented femoral component with taper design. A prospective study.
Pitto RP, Schramm M, Hohmann D, Schmidt R
Chir Organi Mov 2001 Apr-Jun;86(2):87-97. PMID: 12025051
Total hip arthroplasty using an uncemented femoral component with taper design: outcome at 10-year follow-up.
Schramm M, Keck F, Hohmann D, Pitto RP
Arch Orthop Trauma Surg 2000;120(7-8):407-12. doi: 10.1007/pl00013771. PMID: 10968528
Bisphosphonate therapy of reflex sympathetic dystrophy syndrome.
Adami S, Fossaluzza V, Gatti D, Fracassi E, Braga V
Ann Rheum Dis 1997 Mar;56(3):201-4. doi: 10.1136/ard.56.3.201. PMID: 9135227Free PMC Article
Hip arthroplasty using the cementless CLS stem. A 2--4-year experience.
Robinson RP, Lovell TP, Green TM
J Arthroplasty 1994 Apr;9(2):177-92. doi: 10.1016/0883-5403(94)90067-1. PMID: 8014649

Diagnosis

Asymmetric presentation with a novel RP2 gene mutation in X-Linked retinitis pigmentosa: a case report.
Lee HW, Lee EK
BMC Ophthalmol 2023 May 17;23(1):221. doi: 10.1186/s12886-023-02968-4. PMID: 37198560Free PMC Article
Fumarate hydratase-deficient renal cell carcinoma: a case report and review of the literature.
Lv Y, Song L, Hu M
J Med Case Rep 2023 Apr 20;17(1):182. doi: 10.1186/s13256-023-03841-0. PMID: 37076922Free PMC Article
The Evaluation of the Multiple Myeloma Pathological Osseous Tissue of Microarchitecture.
Chen L, Wang X, Zhang S, Wang W, Su B, Xu X, Lv D, Liu W, Li X, Li Z
Curr Med Imaging 2021;17(4):513-516. doi: 10.2174/1573405616666201015144015. PMID: 33059581
Hematopoietic bone marrow hyperplasia: correlation of spinal MR findings, hematologic parameters, and bone mineral density in endurance athletes.
Caldemeyer KS, Smith RR, Harris A, Williams T, Huang Y, Eckert GJ, Slemenda CW
Radiology 1996 Feb;198(2):503-8. doi: 10.1148/radiology.198.2.8596857. PMID: 8596857

Therapy

Asymmetric presentation with a novel RP2 gene mutation in X-Linked retinitis pigmentosa: a case report.
Lee HW, Lee EK
BMC Ophthalmol 2023 May 17;23(1):221. doi: 10.1186/s12886-023-02968-4. PMID: 37198560Free PMC Article
Zoledronic Acid-Induced Interface Dermatitis.
Succaria F, Collier M, Mahalingam M
Am J Dermatopathol 2015 Dec;37(12):933-5. doi: 10.1097/DAD.0000000000000341. PMID: 26588338Free PMC Article
Bisphosphonate therapy of reflex sympathetic dystrophy syndrome.
Adami S, Fossaluzza V, Gatti D, Fracassi E, Braga V
Ann Rheum Dis 1997 Mar;56(3):201-4. doi: 10.1136/ard.56.3.201. PMID: 9135227Free PMC Article

Prognosis

The bone-vacuum cementing technique for the fixation of the stem in total hip arthroplasty.
Pitto RP, Kessler M, Schikora N, di Muria GV
Chir Organi Mov 2001 Apr-Jun;86(2):99-110. PMID: 12025052
Clinical outcome and quantitative evaluation of periprosthetic bone-remodeling of an uncemented femoral component with taper design. A prospective study.
Pitto RP, Schramm M, Hohmann D, Schmidt R
Chir Organi Mov 2001 Apr-Jun;86(2):87-97. PMID: 12025051
Total hip arthroplasty using an uncemented femoral component with taper design: outcome at 10-year follow-up.
Schramm M, Keck F, Hohmann D, Pitto RP
Arch Orthop Trauma Surg 2000;120(7-8):407-12. doi: 10.1007/pl00013771. PMID: 10968528
Bisphosphonate therapy of reflex sympathetic dystrophy syndrome.
Adami S, Fossaluzza V, Gatti D, Fracassi E, Braga V
Ann Rheum Dis 1997 Mar;56(3):201-4. doi: 10.1136/ard.56.3.201. PMID: 9135227Free PMC Article
Hip arthroplasty using the cementless CLS stem. A 2--4-year experience.
Robinson RP, Lovell TP, Green TM
J Arthroplasty 1994 Apr;9(2):177-92. doi: 10.1016/0883-5403(94)90067-1. PMID: 8014649

Clinical prediction guides

Asymmetric presentation with a novel RP2 gene mutation in X-Linked retinitis pigmentosa: a case report.
Lee HW, Lee EK
BMC Ophthalmol 2023 May 17;23(1):221. doi: 10.1186/s12886-023-02968-4. PMID: 37198560Free PMC Article
Unexpected ultrastructral changes in bone osteiod collagens in osteogenesis imperfecta.
Sarathchandra P, Pope FM
Micron 2005;36(7-8):696-702. Epub 2005 Sep 7 doi: 10.1016/j.micron.2005.07.011. PMID: 16182545
Clinical outcome and quantitative evaluation of periprosthetic bone-remodeling of an uncemented femoral component with taper design. A prospective study.
Pitto RP, Schramm M, Hohmann D, Schmidt R
Chir Organi Mov 2001 Apr-Jun;86(2):87-97. PMID: 12025051
Tc-99m HDP bone scan showing bone changes in a case of tuberous sclerosis or Bourneville's disease.
Jonard P, Lonneux M, Boland B, Malghem J, Jamar F
Clin Nucl Med 2001 Jan;26(1):50-2. doi: 10.1097/00003072-200101000-00011. PMID: 11139053
Bisphosphonate therapy of reflex sympathetic dystrophy syndrome.
Adami S, Fossaluzza V, Gatti D, Fracassi E, Braga V
Ann Rheum Dis 1997 Mar;56(3):201-4. doi: 10.1136/ard.56.3.201. PMID: 9135227Free PMC Article

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