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Abnormal circulating vitamin A concentration

MedGen UID:
870248
•Concept ID:
C4024686
•
Finding
Synonym: Abnormality of vitamin A metabolism
 
HPO: HP:0008372

Definition

Concentration of vitamin A in the blood circulation outside limits of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal circulating vitamin A concentration

Recent clinical studies

Etiology

Micronutrient Status in Adult Crohn's Disease during Clinical Remission: A Systematic Review.
McDonnell M, Sartain S, Westoby C, Katarachia V, Wootton SA, Cummings JRF
Nutrients 2023 Nov 14;15(22) doi: 10.3390/nu15224777. PMID: 38004171Free PMC Article
Baseline Levels of Retinol-Binding Protein 4 and Vitamin A in Healthy Subjects, Stargardt Disease, and Geographic Atrophy Patients.
Janeschitz-Kriegl L, Cattaneo M, Scholl HPN
Ophthalmic Res 2022;65(3):351-360. Epub 2022 Feb 2 doi: 10.1159/000522365. PMID: 35108705
Circulating hormones and breast cancer risk in premenopausal women: a randomized trial of low-dose tamoxifen and fenretinide.
Johansson H, Bonanni B, Gandini S, Guerrieri-Gonzaga A, Cazzaniga M, Serrano D, Macis D, Puccio A, Sandri MT, Gulisano M, Formelli F, Decensi A
Breast Cancer Res Treat 2013 Dec;142(3):569-78. Epub 2013 Nov 17 doi: 10.1007/s10549-013-2768-7. PMID: 24241787
Relationship between vitamin A deficiency, malnutrition, and conjunctival impression cytology.
Fuchs GJ, Ausayakhun S, Ruckphaopunt S, Tansuhaj A, Suskind RM
Am J Clin Nutr 1994 Aug;60(2):293-8. doi: 10.1093/ajcn/60.2.293. PMID: 8030610
Studies on plasma transthyretin (prealbumin) in familial amyloidotic polyneuropathy, Portuguese type.
Saraiva MJ, Costa PP, Goodman DS
J Lab Clin Med 1983 Oct;102(4):590-603. PMID: 6311926

Diagnosis

Growth hormone (GH) treatment decreases postprandial remnant-like particle cholesterol concentration and improves endothelial function in adult-onset GH deficiency.
Twickler TB, Wilmink HW, Schreuder PC, Cabezas MC, van Dam PS, Koppeschaar HP, Erkelens DW, Dallinga-Thie GM
J Clin Endocrinol Metab 2000 Dec;85(12):4683-9. doi: 10.1210/jcem.85.12.7075. PMID: 11134128
Relationship between vitamin A deficiency, malnutrition, and conjunctival impression cytology.
Fuchs GJ, Ausayakhun S, Ruckphaopunt S, Tansuhaj A, Suskind RM
Am J Clin Nutr 1994 Aug;60(2):293-8. doi: 10.1093/ajcn/60.2.293. PMID: 8030610

Therapy

Circulating hormones and breast cancer risk in premenopausal women: a randomized trial of low-dose tamoxifen and fenretinide.
Johansson H, Bonanni B, Gandini S, Guerrieri-Gonzaga A, Cazzaniga M, Serrano D, Macis D, Puccio A, Sandri MT, Gulisano M, Formelli F, Decensi A
Breast Cancer Res Treat 2013 Dec;142(3):569-78. Epub 2013 Nov 17 doi: 10.1007/s10549-013-2768-7. PMID: 24241787
Low levels of alitretinoin in seminal fluids after repeated oral doses in healthy men.
Schmitt-Hoffmann AH, Roos B, Sauer J, Brown T, Weidekamm E, Meyer I, Schleimer M, Maares J
Clin Exp Dermatol 2011 Apr;36 Suppl 2:12-7. doi: 10.1111/j.1365-2230.2011.04032.x. PMID: 21443599
Effect of combination therapy with all-trans-retinoic acid and recombinant human granulocyte colony-stimulating factor in patients with myelodysplastic syndromes.
Ganser A, Seipelt G, Verbeek W, Ottmann OG, Maurer A, Kolbe K, Hess U, Elsner S, Reutzel R, Wörmann B
Leukemia 1994 Mar;8(3):369-75. PMID: 7510354
Severe defect in clearing postprandial chylomicron remnants in dialysis patients.
Weintraub M, Burstein A, Rassin T, Liron M, Ringel Y, Cabili S, Blum M, Peer G, Iaina A
Kidney Int 1992 Nov;42(5):1247-52. doi: 10.1038/ki.1992.411. PMID: 1453610
Primary biliary cirrhosis, dark adaptometry, electro-oculography, and vitamin A state.
Shepherd AN, Bedford GJ, Hill A, Bouchier IA
Br Med J (Clin Res Ed) 1984 Dec 1;289(6457):1484-5. doi: 10.1136/bmj.289.6457.1484. PMID: 6439282Free PMC Article

Prognosis

Circulating hormones and breast cancer risk in premenopausal women: a randomized trial of low-dose tamoxifen and fenretinide.
Johansson H, Bonanni B, Gandini S, Guerrieri-Gonzaga A, Cazzaniga M, Serrano D, Macis D, Puccio A, Sandri MT, Gulisano M, Formelli F, Decensi A
Breast Cancer Res Treat 2013 Dec;142(3):569-78. Epub 2013 Nov 17 doi: 10.1007/s10549-013-2768-7. PMID: 24241787

Clinical prediction guides

Studies on plasma transthyretin (prealbumin) in familial amyloidotic polyneuropathy, Portuguese type.
Saraiva MJ, Costa PP, Goodman DS
J Lab Clin Med 1983 Oct;102(4):590-603. PMID: 6311926

Recent systematic reviews

Micronutrient Status in Adult Crohn's Disease during Clinical Remission: A Systematic Review.
McDonnell M, Sartain S, Westoby C, Katarachia V, Wootton SA, Cummings JRF
Nutrients 2023 Nov 14;15(22) doi: 10.3390/nu15224777. PMID: 38004171Free PMC Article

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