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Chronic irritative conjunctivitis

MedGen UID:
870366
•Concept ID:
C4024810
•
Disease or Syndrome
HPO: HP:0007717

Definition

A chronic irritative conjunctivitis, which commonly presents with general irritation and redness of the eyes, with a burning, dry, or foreign-body sensation of the eyes. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic irritative conjunctivitis

Conditions with this feature

Onychotrichodysplasia and neutropenia
MedGen UID:
340512
•Concept ID:
C1850316
•
Disease or Syndrome
See: Condition Record
Onychotrichodysplasia and neutropenia

Professional guidelines

PubMed

Management of patients with ocular manifestations in vesiculobullous disorders affecting the mouth.
Hansen MS, Klefter ON, Julian HO, Lynge Pedersen AM, Heegaard S
Oral Dis 2017 Oct;23(7):849-853. Epub 2016 Nov 17 doi: 10.1111/odi.12590. PMID: 27717107
Systemic treatment for blepharokeratoconjunctivitis in children.
O'Gallagher M, Banteka M, Bunce C, Larkin F, Tuft S, Dahlmann-Noor A
Cochrane Database Syst Rev 2016 May 30;2016(5):CD011750. doi: 10.1002/14651858.CD011750.pub2. PMID: 27236587Free PMC Article
Ocular allergy: diagnosis and treatment.
Butrus S, Portela R
Ophthalmol Clin North Am 2005 Dec;18(4):485-92, v. doi: 10.1016/j.ohc.2005.07.007. PMID: 16314214

Recent clinical studies

Etiology

Floppy Eyelid Syndrome: An Unfamiliar Entity for Plastic Surgeons.
Lee CC, Lai HT, Kuo YR, Lee SS, Lai CS
Ann Plast Surg 2018 Feb;80(2S Suppl 1):S40-S47. doi: 10.1097/SAP.0000000000001311. PMID: 29369905
Topical treatments for blepharokeratoconjunctivitis in children.
O'Gallagher M, Bunce C, Hingorani M, Larkin F, Tuft S, Dahlmann-Noor A
Cochrane Database Syst Rev 2017 Feb 7;2(2):CD011965. doi: 10.1002/14651858.CD011965.pub2. PMID: 28170093Free PMC Article
Hydrogen sulfide intoxication.
Guidotti TL
Handb Clin Neurol 2015;131:111-33. doi: 10.1016/B978-0-444-62627-1.00008-1. PMID: 26563786
Atopic keratoconjunctivitis: A review.
Chen JJ, Applebaum DS, Sun GS, Pflugfelder SC
J Am Acad Dermatol 2014 Mar;70(3):569-75. Epub 2013 Dec 15 doi: 10.1016/j.jaad.2013.10.036. PMID: 24342754
Blepharitis.
Bernardes TF, Bonfioli AA
Semin Ophthalmol 2010 May;25(3):79-83. doi: 10.3109/08820538.2010.488562. PMID: 20590417

Diagnosis

Keratinocytes: An Enigmatic Factor in Atopic Dermatitis.
Das P, Mounika P, Yellurkar ML, Prasanna VS, Sarkar S, Velayutham R, Arumugam S
Cells 2022 May 19;11(10) doi: 10.3390/cells11101683. PMID: 35626720Free PMC Article
Mucus fishing syndrome.
Chiew RLJ, Au Eong DTM, Au Eong KG
BMJ Case Rep 2022 Apr 8;15(4) doi: 10.1136/bcr-2022-249188. PMID: 35396241Free PMC Article
Superior limbic keratoconjunctivitis: a comprehensive review.
Lahoti S, Weiss M, Johnson DA, Kheirkhah A
Surv Ophthalmol 2022 Mar-Apr;67(2):331-341. Epub 2021 May 30 doi: 10.1016/j.survophthal.2021.05.009. PMID: 34077767
Floppy eyelid syndrome: A comprehensive review.
Salinas R, Puig M, Fry CL, Johnson DA, Kheirkhah A
Ocul Surf 2020 Jan;18(1):31-39. Epub 2019 Oct 5 doi: 10.1016/j.jtos.2019.10.002. PMID: 31593763
Blepharitis.
Bernardes TF, Bonfioli AA
Semin Ophthalmol 2010 May;25(3):79-83. doi: 10.3109/08820538.2010.488562. PMID: 20590417

Therapy

Topical treatments for blepharokeratoconjunctivitis in children.
O'Gallagher M, Bunce C, Hingorani M, Larkin F, Tuft S, Dahlmann-Noor A
Cochrane Database Syst Rev 2017 Feb 7;2(2):CD011965. doi: 10.1002/14651858.CD011965.pub2. PMID: 28170093Free PMC Article
Management of patients with ocular manifestations in vesiculobullous disorders affecting the mouth.
Hansen MS, Klefter ON, Julian HO, Lynge Pedersen AM, Heegaard S
Oral Dis 2017 Oct;23(7):849-853. Epub 2016 Nov 17 doi: 10.1111/odi.12590. PMID: 27717107
Systemic treatment for blepharokeratoconjunctivitis in children.
O'Gallagher M, Banteka M, Bunce C, Larkin F, Tuft S, Dahlmann-Noor A
Cochrane Database Syst Rev 2016 May 30;2016(5):CD011750. doi: 10.1002/14651858.CD011750.pub2. PMID: 27236587Free PMC Article
Atopic keratoconjunctivitis: A review.
Chen JJ, Applebaum DS, Sun GS, Pflugfelder SC
J Am Acad Dermatol 2014 Mar;70(3):569-75. Epub 2013 Dec 15 doi: 10.1016/j.jaad.2013.10.036. PMID: 24342754
Ocular allergy: diagnosis and treatment.
Butrus S, Portela R
Ophthalmol Clin North Am 2005 Dec;18(4):485-92, v. doi: 10.1016/j.ohc.2005.07.007. PMID: 16314214

Prognosis

Floppy Eyelid Syndrome: an Overlooked Comorbidity Among Bariatric Patients.
Zoumpou T, Samuel S, Torun N, Yadav P, Jones DB
Obes Surg 2023 Feb;33(2):523-529. Epub 2022 Dec 26 doi: 10.1007/s11695-022-06410-4. PMID: 36567378
Mucus fishing syndrome.
Chiew RLJ, Au Eong DTM, Au Eong KG
BMJ Case Rep 2022 Apr 8;15(4) doi: 10.1136/bcr-2022-249188. PMID: 35396241Free PMC Article
Floppy Eyelid Syndrome: An Unfamiliar Entity for Plastic Surgeons.
Lee CC, Lai HT, Kuo YR, Lee SS, Lai CS
Ann Plast Surg 2018 Feb;80(2S Suppl 1):S40-S47. doi: 10.1097/SAP.0000000000001311. PMID: 29369905
Hydrogen sulfide intoxication.
Guidotti TL
Handb Clin Neurol 2015;131:111-33. doi: 10.1016/B978-0-444-62627-1.00008-1. PMID: 26563786
Atopic keratoconjunctivitis: A review.
Chen JJ, Applebaum DS, Sun GS, Pflugfelder SC
J Am Acad Dermatol 2014 Mar;70(3):569-75. Epub 2013 Dec 15 doi: 10.1016/j.jaad.2013.10.036. PMID: 24342754

Clinical prediction guides

Potential factors affecting chronic chemical intolerance associated with constitutional predisposition or lifestyle and environment during childhood: From a six-year follow-up study.
Azuma K, Uchiyama I, Kunugita N
J Psychosom Res 2021 Dec;151:110665. Epub 2021 Nov 2 doi: 10.1016/j.jpsychores.2021.110665. PMID: 34763204
Evaluation of ocular symptoms in COVID-19 subjects in inpatient and outpatient settings.
Sezgin Akçay Bİ, Kardeş E, Kıray G, Ayaz B, Karakuş Hacıoğlu G, Pala E
Int Ophthalmol 2021 Apr;41(4):1541-1548. Epub 2021 Jan 24 doi: 10.1007/s10792-021-01728-x. PMID: 33486649Free PMC Article
Topical treatments for blepharokeratoconjunctivitis in children.
O'Gallagher M, Bunce C, Hingorani M, Larkin F, Tuft S, Dahlmann-Noor A
Cochrane Database Syst Rev 2017 Feb 7;2(2):CD011965. doi: 10.1002/14651858.CD011965.pub2. PMID: 28170093Free PMC Article
Vernal keratoconjunctivitis: a severe allergic eye disease with remodeling changes.
Vichyanond P, Pacharn P, Pleyer U, Leonardi A
Pediatr Allergy Immunol 2014 Jun;25(4):314-22. Epub 2014 Jan 20 doi: 10.1111/pai.12197. PMID: 24438133
Evaluation of the adult patient with atopic dermatitis.
de Bruin Weller MS, Rockmann H, Knulst AC, Bruijnzeel-Koomen CA
Clin Exp Allergy 2013 Mar;43(3):279-91. doi: 10.1111/cea.12030. PMID: 23414536

Recent systematic reviews

Interventions for chronic palmoplantar pustulosis.
Obeid G, Do G, Kirby L, Hughes C, Sbidian E, Le Cleach L
Cochrane Database Syst Rev 2020 Jan 20;1(1):CD011628. doi: 10.1002/14651858.CD011628.pub2. PMID: 31958161Free PMC Article
Topical treatments for blepharokeratoconjunctivitis in children.
O'Gallagher M, Bunce C, Hingorani M, Larkin F, Tuft S, Dahlmann-Noor A
Cochrane Database Syst Rev 2017 Feb 7;2(2):CD011965. doi: 10.1002/14651858.CD011965.pub2. PMID: 28170093Free PMC Article
Systemic treatment for blepharokeratoconjunctivitis in children.
O'Gallagher M, Banteka M, Bunce C, Larkin F, Tuft S, Dahlmann-Noor A
Cochrane Database Syst Rev 2016 May 30;2016(5):CD011750. doi: 10.1002/14651858.CD011750.pub2. PMID: 27236587Free PMC Article

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