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Intestinal carcinoid

MedGen UID:: 870540
•Concept ID:: C4024988
•: Neoplastic Process

HPO:	HP:0006723

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVIntestinal carcinoid

Phenotypic abnormality
- Neoplasm
  - Neoplasm by anatomical site
    - Neoplasm of the endocrine system
      - Neuroendocrine neoplasm
        Carcinoid tumor
        Intestinal carcinoid

Conditions with this feature

Carcinoid tumor of intestine

MedGen UID:: 138099
•Concept ID:: C0349535
•: Neoplastic Process

A well differentiated, low grade neuroendocrine neoplasm (carcinoid tumor) that arises from the small or large intestine. The mitotic count is less than 2 per 10 HPF and/or the Ki67 index is equal to or less than 2 percent.

See: Condition Record

Carcinoid tumor of intestine

Professional guidelines

PubMed

Diagnosis and treatment in intestinal carcinoid tumors.

Taal BG
Curr Gastroenterol Rep 2005 Feb;7(1):1-3. doi: 10.1007/s11894-005-0057-2. PMID: 15701288

Serum neuron-specific enolase in diagnosis and follow-up of gastrointestinal neuroendocrine tumors.

D'Alessandro M, Mariani P, Lomanto D, Carlei F, Lezoche E, Speranza V
Tumour Biol 1992;13(5-6):352-7. doi: 10.1159/000217786. PMID: 1290031

Nuclear DNA in intestinal carcinoid tumors. A study before and after cytotoxin (streptozotocin and 5-fluorouracil) treatment.

Wilander E, Bengtsson A, Lindgren PG, Lundqvist M, Norheim I, Oberg K
Cancer 1985 Aug 15;56(4):793-6. doi: 10.1002/1097-0142(19850815)56:4<793::aid-cncr2820560416>3.0.co;2-w. PMID: 3160455

See all (4)

Recent clinical studies

Etiology

A Hereditary Form of Small Intestinal Carcinoid Associated With a Germline Mutation in Inositol Polyphosphate Multikinase.

Sei Y, Zhao X, Forbes J, Szymczak S, Li Q, Trivedi A, Voellinger M, Joy G, Feng J, Whatley M, Jones MS, Harper UL, Marx SJ, Venkatesan AM, Chandrasekharappa SC, Raffeld M, Quezado MM, Louie A, Chen CC, Lim RM, Agarwala R, Schäffer AA, Hughes MS, Bailey-Wilson JE, Wank SA
Gastroenterology 2015 Jul;149(1):67-78. Epub 2015 Apr 9 doi: 10.1053/j.gastro.2015.04.008. PMID: 25865046 Free PMC Article

Laparoscopic resection of primary midgut carcinoid tumors.

Reissman P, Shmailov S, Grozinsky-Glasberg S, Gross DJ
Surg Endosc 2013 Oct;27(10):3678-82. Epub 2013 Apr 10 doi: 10.1007/s00464-013-2944-1. PMID: 23572224

Familial risk of small intestinal carcinoid and adenocarcinoma.

Kharazmi E, Pukkala E, Sundquist K, Hemminki K
Clin Gastroenterol Hepatol 2013 Aug;11(8):944-9. Epub 2013 Mar 15 doi: 10.1016/j.cgh.2013.02.025. PMID: 23500615

Carcinoid tumours of the testis.

Stroosma OB, Delaere KP
BJU Int 2008 May;101(9):1101-5. Epub 2008 Jan 8 doi: 10.1111/j.1464-410X.2007.07360.x. PMID: 18190641

Detection of small-bowel neuroendocrine tumors by video capsule endoscopy.

van Tuyl SA, van Noorden JT, Timmer R, Stolk MF, Kuipers EJ, Taal BG
Gastrointest Endosc 2006 Jul;64(1):66-72. doi: 10.1016/j.gie.2006.01.054. PMID: 16813805

See all (29)

Diagnosis

Familial risk of small intestinal carcinoid and adenocarcinoma.

Kharazmi E, Pukkala E, Sundquist K, Hemminki K
Clin Gastroenterol Hepatol 2013 Aug;11(8):944-9. Epub 2013 Mar 15 doi: 10.1016/j.cgh.2013.02.025. PMID: 23500615

Concurrent small bowel adenocarcinoma and carcinoid tumor in Crohn's disease--case report and literature review.

Boltin D, Levi Z, Halpern M, Fraser GM
J Crohns Colitis 2011 Oct;5(5):461-4. Epub 2011 May 10 doi: 10.1016/j.crohns.2011.04.006. PMID: 21939921

Carcinoid tumours of the testis.

Stroosma OB, Delaere KP
BJU Int 2008 May;101(9):1101-5. Epub 2008 Jan 8 doi: 10.1111/j.1464-410X.2007.07360.x. PMID: 18190641

CTGF, intestinal stellate cells and carcinoid fibrogenesis.

Kidd M, Modlin I, Shapiro M, Camp R, Mane S, Usinger W, Murren J
World J Gastroenterol 2007 Oct 21;13(39):5208-16. doi: 10.3748/wjg.v13.i39.5208. PMID: 17876891 Free PMC Article

Carcinoid tumors and fibrosis: an association with no explanation.

Modlin IM, Shapiro MD, Kidd M
Am J Gastroenterol 2004 Dec;99(12):2466-78. doi: 10.1111/j.1572-0241.2004.40507.x. PMID: 15571597

See all (42)

Therapy

Risk of Radiation Exposure to Clinical Staff from Paracenteses of Large-Volume Chylous Ascites After (177)Lu-DOTATATE Infusion.

Tipnis S, Rieter WJ, Henderson-Suite V, Gordon L
J Nucl Med Technol 2022 Sep;50(3):274-277. Epub 2021 Dec 21 doi: 10.2967/jnmt.121.262820. PMID: 34933922

Primary Metastatic Small Intestinal Carcinoid Tumor Without Carcinoid Syndrome.

Anthony LB
Oncology (Williston Park) 2015 Oct;29(10):755-6, 759. PMID: 26470900

Orthotopic liver transplantation for carcinoid tumour metastatic to the liver: anesthetic management.

Claure RE, Drover DD, Haddow GR, Esquivel CO, Angst MS
Can J Anaesth 2000 Apr;47(4):334-7. doi: 10.1007/BF03020948. PMID: 10764178

The effects of octreotide on basal and stimulated hormone levels in patients with carcinoid syndrome.

Oberg K, Norheim I, Theodorsson E, Ahlman H, Lundqvist G, Wide L
J Clin Endocrinol Metab 1989 Apr;68(4):796-800. doi: 10.1210/jcem-68-4-796. PMID: 2466045

Effects of leukocyte interferon on clinical symptoms and hormone levels in patients with mid-gut carcinoid tumors and carcinoid syndrome.

Oberg K, Funa K, Alm G
N Engl J Med 1983 Jul 21;309(3):129-33. doi: 10.1056/NEJM198307213090301. PMID: 6191217

See all (16)

Prognosis

Familial risk of small intestinal carcinoid and adenocarcinoma.

Kharazmi E, Pukkala E, Sundquist K, Hemminki K
Clin Gastroenterol Hepatol 2013 Aug;11(8):944-9. Epub 2013 Mar 15 doi: 10.1016/j.cgh.2013.02.025. PMID: 23500615

Carcinoid tumours of the testis.

Stroosma OB, Delaere KP
BJU Int 2008 May;101(9):1101-5. Epub 2008 Jan 8 doi: 10.1111/j.1464-410X.2007.07360.x. PMID: 18190641

The role of genetic markers--NAP1L1, MAGE-D2, and MTA1--in defining small-intestinal carcinoid neoplasia.

Kidd M, Modlin IM, Mane SM, Camp RL, Eick G, Latich I
Ann Surg Oncol 2006 Feb;13(2):253-62. Epub 2006 Jan 20 doi: 10.1245/ASO.2006.12.011. PMID: 16424981

Carcinoid tumors and fibrosis: an association with no explanation.

Modlin IM, Shapiro MD, Kidd M
Am J Gastroenterol 2004 Dec;99(12):2466-78. doi: 10.1111/j.1572-0241.2004.40507.x. PMID: 15571597

Carcinomas of the breast with endocrine differentiation: a review.

Maluf HM, Koerner FC
Virchows Arch 1994;425(5):449-57. doi: 10.1007/BF00197547. PMID: 7850068

See all (22)

Clinical prediction guides

Vitamin D and vitamin B(12) deficiencies in patients with small intestinal carcinoid tumour: is opioid use disorder a confounding factor in the diagnosis?

Fagan R, Bokhari SSN, Inayat F
BMJ Case Rep 2019 Mar 16;12(3) doi: 10.1136/bcr-2018-227430. PMID: 30878964 Free PMC Article

A Hereditary Form of Small Intestinal Carcinoid Associated With a Germline Mutation in Inositol Polyphosphate Multikinase.

CTGF, intestinal stellate cells and carcinoid fibrogenesis.

Kidd M, Modlin I, Shapiro M, Camp R, Mane S, Usinger W, Murren J
World J Gastroenterol 2007 Oct 21;13(39):5208-16. doi: 10.3748/wjg.v13.i39.5208. PMID: 17876891 Free PMC Article

Solitary versus multiple carcinoid tumors of the ileum: a clinical and pathologic review of 68 cases.

Yantiss RK, Odze RD, Farraye FA, Rosenberg AE
Am J Surg Pathol 2003 Jun;27(6):811-7. doi: 10.1097/00000478-200306000-00013. PMID: 12766586

Biochemical diagnosis of gastroenteropancreatic endocrine tumors.

Tartaglia A, Bianchini S, Vezzadini P
Minerva Med 2003 Feb;94(1):1-7. PMID: 12719697

See all (21)

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Intestinal carcinoid

Term Hierarchy

Conditions with this feature

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

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