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Posterior fusion of lumbosacral vertebrae

MedGen UID:
870715
Concept ID:
C4025169
Finding
HPO: HP:0005626

Definition

Bony fusion of the posterior part of the L5 vertebral body with the sacrum. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPosterior fusion of lumbosacral vertebrae

Conditions with this feature

Posterior fusion of lumbosacral vertebrae-blepharoptosis syndrome
MedGen UID:
348108
Concept ID:
C1860464
Disease or Syndrome
A rare syndrome characterized by congenital ptosis and posterior fusion of the lumbosacral vertebrae. It has been described in a mother and her two daughters.

Professional guidelines

PubMed

Chang CW, Fu TS, Chen WJ, Chen CW, Lai PL, Chen SH
World Neurosurg 2019 Jun;126:e330-e341. Epub 2019 Feb 26 doi: 10.1016/j.wneu.2019.02.050. PMID: 30822594
Ledbetter LN, Salzman KL, Sanders RK, Shah LM
Radiographics 2016 May-Jun;36(3):783-99. Epub 2016 Apr 8 doi: 10.1148/rg.2016150121. PMID: 27058729
Jeanneret B, Magerl F
J Spinal Disord 1994 Jun;7(3):185-205. doi: 10.1097/00002517-199407030-00001. PMID: 7919642

Recent clinical studies

Etiology

Rathbone J, Rackham M, Nielsen D, Lee SM, Hing W, Riar S, Scott-Young M
Eur Spine J 2023 Jun;32(6):1911-1926. Epub 2023 Apr 18 doi: 10.1007/s00586-023-07567-x. PMID: 37071155
Preston G, Hoffmann J, Satin A, Derman PB, Khalil JG
J Am Acad Orthop Surg 2023 Apr 1;31(7):e356-e365. doi: 10.5435/JAAOS-D-22-00956. PMID: 36877764
Gong K, Lin Y, Wang Z, Li F, Xiong W
BMC Musculoskelet Disord 2022 Oct 14;23(1):914. doi: 10.1186/s12891-022-05855-z. PMID: 36242007Free PMC Article
Fenton-White HA
Spine J 2021 Sep;21(9):1528-1541. Epub 2021 Mar 20 doi: 10.1016/j.spinee.2021.03.016. PMID: 33757870
Li Y, Wang G, Jiang Z, Cui X, Li T, Liu X, Zhang W, Sun J
Medicine (Baltimore) 2017 Oct;96(43):e8393. doi: 10.1097/MD.0000000000008393. PMID: 29069034Free PMC Article

Diagnosis

Choi J, Kim JS, Hyun SJ, Kim KJ, Kim HJ, Deletis V, Park KS
Clin Neurophysiol 2022 Dec;144:59-66. Epub 2022 Oct 12 doi: 10.1016/j.clinph.2022.09.020. PMID: 36274572
Kammien AJ, Zhu JR, Gillinov SM, Gouzoulis MJ, Grauer JN
J Am Acad Orthop Surg 2022 Jun 1;30(11):528-533. Epub 2022 Feb 28 doi: 10.5435/JAAOS-D-21-01121. PMID: 35234736
Cha EDK, Lynch CP, Patel MR, Jacob KC, Geoghegan CE, Jadczak CN, Mohan S, Singh K
Neurosurgery 2022 Feb 1;90(2):215-220. doi: 10.1227/NEU.0000000000001782. PMID: 34995271
Ledbetter LN, Salzman KL, Sanders RK, Shah LM
Radiographics 2016 May-Jun;36(3):783-99. Epub 2016 Apr 8 doi: 10.1148/rg.2016150121. PMID: 27058729
Lee CS, Hwang CJ, Lee DH, Kim YT, Lee HS
Clin Orthop Surg 2011 Mar;3(1):39-47. Epub 2011 Feb 15 doi: 10.4055/cios.2011.3.1.39. PMID: 21369477Free PMC Article

Therapy

Rathbone J, Rackham M, Nielsen D, Lee SM, Hing W, Riar S, Scott-Young M
Eur Spine J 2023 Jun;32(6):1911-1926. Epub 2023 Apr 18 doi: 10.1007/s00586-023-07567-x. PMID: 37071155
Gong K, Lin Y, Wang Z, Li F, Xiong W
BMC Musculoskelet Disord 2022 Oct 14;23(1):914. doi: 10.1186/s12891-022-05855-z. PMID: 36242007Free PMC Article
de Kunder SL, van Kuijk SMJ, Rijkers K, Caelers IJMH, van Hemert WLW, de Bie RA, van Santbrink H
Spine J 2017 Nov;17(11):1712-1721. Epub 2017 Jun 21 doi: 10.1016/j.spinee.2017.06.018. PMID: 28647584
Galimberti F, Lubelski D, Healy AT, Wang T, Abdullah KG, Nowacki AS, Benzel EC, Mroz TE
Spine (Phila Pa 1976) 2015 Jul 15;40(14):1132-9. doi: 10.1097/BRS.0000000000000971. PMID: 25955186
Chrastil J, Patel AA
J Am Acad Orthop Surg 2012 May;20(5):283-91. doi: 10.5435/JAAOS-20-05-283. PMID: 22553100

Prognosis

Jo DJ, Seo EM
PLoS One 2021;16(9):e0257316. Epub 2021 Sep 10 doi: 10.1371/journal.pone.0257316. PMID: 34506593Free PMC Article
Xue X, Zhao S, Miao F, Li K
Int Orthop 2020 May;44(5):979-986. Epub 2020 Mar 20 doi: 10.1007/s00264-020-04537-6. PMID: 32198669
Cui JJ, Gala RJ, Ondeck NT, McLynn RP, Bovonratwet P, Shultz B, Grauer JN
Spine J 2019 Apr;19(4):631-636. Epub 2018 Sep 13 doi: 10.1016/j.spinee.2018.09.004. PMID: 30219360
Aono H, Takenaka S, Nagamoto Y, Tobimatsu H, Yamashita T, Furuya M, Iwasaki M
World Neurosurg 2018 Apr;112:e473-e478. Epub 2018 Jan 31 doi: 10.1016/j.wneu.2018.01.062. PMID: 29355805
Li Y, Wang G, Jiang Z, Cui X, Li T, Liu X, Zhang W, Sun J
Medicine (Baltimore) 2017 Oct;96(43):e8393. doi: 10.1097/MD.0000000000008393. PMID: 29069034Free PMC Article

Clinical prediction guides

Rathbone J, Rackham M, Nielsen D, Lee SM, Hing W, Riar S, Scott-Young M
Eur Spine J 2023 Jun;32(6):1911-1926. Epub 2023 Apr 18 doi: 10.1007/s00586-023-07567-x. PMID: 37071155
Liu D, Shi B, Li Y, Liu Z, Sun X, Zhu Z, Qiu Y
Orthop Surg 2022 Jul;14(7):1413-1419. Epub 2022 Jun 9 doi: 10.1111/os.13317. PMID: 35678133Free PMC Article
Segawa T, Koga H, Oshina M, Ishibashi K, Takano Y, Iwai H, Inanami H
Medicina (Kaunas) 2021 Feb 3;57(2) doi: 10.3390/medicina57020135. PMID: 33546404Free PMC Article
Li Y, Wang G, Jiang Z, Cui X, Li T, Liu X, Zhang W, Sun J
Medicine (Baltimore) 2017 Oct;96(43):e8393. doi: 10.1097/MD.0000000000008393. PMID: 29069034Free PMC Article
de Kunder SL, van Kuijk SMJ, Rijkers K, Caelers IJMH, van Hemert WLW, de Bie RA, van Santbrink H
Spine J 2017 Nov;17(11):1712-1721. Epub 2017 Jun 21 doi: 10.1016/j.spinee.2017.06.018. PMID: 28647584

Recent systematic reviews

Rathbone J, Rackham M, Nielsen D, Lee SM, Hing W, Riar S, Scott-Young M
Eur Spine J 2023 Jun;32(6):1911-1926. Epub 2023 Apr 18 doi: 10.1007/s00586-023-07567-x. PMID: 37071155
Formica M, Quarto E, Zanirato A, Mosconi L, Lontaro-Baracchini M, Alessio-Mazzola M, Felli L
Eur Spine J 2021 Jan;30(1):50-62. Epub 2020 Sep 15 doi: 10.1007/s00586-020-06598-y. PMID: 32930843
de Kunder SL, van Kuijk SMJ, Rijkers K, Caelers IJMH, van Hemert WLW, de Bie RA, van Santbrink H
Spine J 2017 Nov;17(11):1712-1721. Epub 2017 Jun 21 doi: 10.1016/j.spinee.2017.06.018. PMID: 28647584
Galimberti F, Lubelski D, Healy AT, Wang T, Abdullah KG, Nowacki AS, Benzel EC, Mroz TE
Spine (Phila Pa 1976) 2015 Jul 15;40(14):1132-9. doi: 10.1097/BRS.0000000000000971. PMID: 25955186
Lee CS, Hwang CJ, Lee DH, Kim YT, Lee HS
Clin Orthop Surg 2011 Mar;3(1):39-47. Epub 2011 Feb 15 doi: 10.4055/cios.2011.3.1.39. PMID: 21369477Free PMC Article

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