U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal nasolabial region morphology

MedGen UID:
870766
•Concept ID:
C4025223
•
Anatomical Abnormality
Synonyms: Abnormality of the nasolabial region; Anomaly of the nasolabial region; Deformity of the nasolabial region; Malformation of the nasolabial region
 
HPO: HP:0005289

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal nasolabial region morphology

Professional guidelines

PubMed

Nasal malformations associated with unilateral cleft lip. Accurate diagnosis and management.
Talmant JC
Scand J Plast Reconstr Surg Hand Surg 1993 Sep;27(3):183-91. doi: 10.3109/02844319309078110. PMID: 8272769

Recent clinical studies

Etiology

Is the Nasolabial Region Symmetric in Individuals With Cleft Lip and Palate?
Dindaroglu F, Dogan E, Dogan S
Cleft Palate Craniofac J 2024 Jan;61(1):12-19. Epub 2022 Aug 1 doi: 10.1177/10556656221116535. PMID: 35912442
Interferon regulatory factor 6 variants affect nasolabial morphology in East Asian populations.
Tomita D, Yamaguchi T, Nakawaki T, Hikita Y, Adel M, Kim YI, Haga S, Takahashi M, Kawaguchi A, Isa M, Park SB, Ishida H, Maki K, Kimura R
Arch Oral Biol 2018 Jan;85:142-147. Epub 2017 Oct 9 doi: 10.1016/j.archoralbio.2017.10.005. PMID: 29065370
Aesthetic evaluation of the nasolabial region in children with unilateral cleft lip and palate comparing expert versus nonexperience health professionals.
Paiva TS, Andre M, Paiva WS, Mattos BS
Biomed Res Int 2014;2014:460106. Epub 2014 Jul 13 doi: 10.1155/2014/460106. PMID: 25126560Free PMC Article
Nasal airway and septal variation in unilateral and bilateral cleft lip and palate.
Starbuck JM, Friel MT, Ghoneima A, Flores RL, Tholpady S, Kula K
Clin Anat 2014 Oct;27(7):999-1008. Epub 2014 Jun 26 doi: 10.1002/ca.22428. PMID: 24976342
Three-dimensional soft tissue change after paranasal augmentation with porous polyethylene.
Kwon TG, Kang SM, Hwang HD
Int J Oral Maxillofac Surg 2014 Jul;43(7):816-23. Epub 2014 Mar 27 doi: 10.1016/j.ijom.2014.03.004. PMID: 24685262

Diagnosis

Identification of a novel pathogenic mutation of the MYH3 gene in a family with distal arthrogryposis type 2B.
Wang WB, Kong LC, Zuo RT, Kang QL
Mol Med Rep 2020 Jan;21(1):438-444. Epub 2019 Nov 15 doi: 10.3892/mmr.2019.10820. PMID: 31746383
Three-dimensional assessment of facial asymmetry in preschool patients with orofacial clefts after neonatal cheiloplasty.
Moslerová V, Dadáková M, Dupej J, Hoffmannova E, Borský J, Černý M, Bejda P, Kočandrlová K, Velemínská J
Int J Pediatr Otorhinolaryngol 2018 May;108:40-45. Epub 2018 Feb 16 doi: 10.1016/j.ijporl.2018.02.023. PMID: 29605363
Outcome of In Situ Septoplasty and Extracorporeal Subtotal Septal Reconstruction in Crooked Noses: A Randomized Self-Controlled Study.
Gode S, Benzer M, Uslu M, Kaya I, Midilli R, Karci B
Aesthetic Plast Surg 2018 Feb;42(1):234-243. Epub 2017 Oct 12 doi: 10.1007/s00266-017-0973-1. PMID: 29026961
Nasal changes after orthognathic surgery for patients with prognathism and Class III malocclusion: analysis using three-dimensional photogrammetry.
Worasakwutiphong S, Chuang YF, Chang HW, Lin HH, Lin PJ, Lo LJ
J Formos Med Assoc 2015 Feb;114(2):112-23. Epub 2014 Dec 20 doi: 10.1016/j.jfma.2014.10.003. PMID: 25534453
Anthropometry for syndromology.
Lakshminarayana P, Janardhan K, David HS
Indian J Pediatr 1991 Mar-Apr;58(2):253-8. doi: 10.1007/BF02751131. PMID: 1879907

Therapy

Three-dimensional assessment of facial asymmetry in preschool patients with orofacial clefts after neonatal cheiloplasty.
Moslerová V, Dadáková M, Dupej J, Hoffmannova E, Borský J, Černý M, Bejda P, Kočandrlová K, Velemínská J
Int J Pediatr Otorhinolaryngol 2018 May;108:40-45. Epub 2018 Feb 16 doi: 10.1016/j.ijporl.2018.02.023. PMID: 29605363
Judgment of Nasolabial Esthetics in Cleft Lip and Palate Is Not Influenced by Overall Facial Attractiveness.
Kocher K, Kowalski P, Kolokitha OE, Katsaros C, Fudalej PS
Cleft Palate Craniofac J 2016 May;53(3):e45-52. Epub 2015 May 1 doi: 10.1597/14-019. PMID: 25932752
Nasal changes after orthognathic surgery for patients with prognathism and Class III malocclusion: analysis using three-dimensional photogrammetry.
Worasakwutiphong S, Chuang YF, Chang HW, Lin HH, Lin PJ, Lo LJ
J Formos Med Assoc 2015 Feb;114(2):112-23. Epub 2014 Dec 20 doi: 10.1016/j.jfma.2014.10.003. PMID: 25534453
Aesthetic evaluation of the nasolabial region in children with unilateral cleft lip and palate comparing expert versus nonexperience health professionals.
Paiva TS, Andre M, Paiva WS, Mattos BS
Biomed Res Int 2014;2014:460106. Epub 2014 Jul 13 doi: 10.1155/2014/460106. PMID: 25126560Free PMC Article
Nasolabial aesthetics.
Mitchell C, Oeltjen J, Panthaki Z, Thaller SR
J Craniofac Surg 2007 Jul;18(4):756-65. doi: 10.1097/scs.0b013e3180684360. PMID: 17667661

Prognosis

Dynamic Nasolabial Growth After Primary Surgery for Patients With Bilateral Cleft Lip: A Five-Year Follow-Up Study.
Wei Y, Zhong T, Yin X, Shi B, Zheng Q, Li J
J Oral Maxillofac Surg 2019 Oct;77(10):2125.e1-2125.e10. Epub 2019 May 30 doi: 10.1016/j.joms.2019.05.013. PMID: 31238020
Active Presurgical Infant Orthopedics for Unilateral Cleft Lip and Palate: Intercenter Outcome Comparison of Latham, Modified McNeil, and Nasoalveolar Molding.
Kornbluth M, Campbell RE, Daskalogiannakis J, Ross EJ, Glick PH, Russell KA, Doucet JC, Hathaway RR, Long RE Jr, Sitzman TJ
Cleft Palate Craniofac J 2018 May;55(5):639-648. Epub 2018 Feb 20 doi: 10.1177/1055665618757367. PMID: 29461877Free PMC Article
A retrospective evaluation of the aesthetics of the nasolabial complex after unilateral cleft lip repair using the Tennison-Randall technique: a study of 44 cases treated in a single cleft center.
Iliopoulos C, Mitsimponas K, Lazaridou D, Neukam FW, Stelzle F
J Craniomaxillofac Surg 2014 Dec;42(8):1679-83. Epub 2014 May 24 doi: 10.1016/j.jcms.2014.05.013. PMID: 24962045
The Eurocleft study: intercenter study of treatment outcome in patients with complete cleft lip and palate. Part 2: craniofacial form and nasolabial appearance.
Brattström V, Mølsted K, Prahl-Andersen B, Semb G, Shaw WC
Cleft Palate Craniofac J 2005 Jan;42(1):69-77. doi: 10.1597/02-119.2.1. PMID: 15643918
Clinical presentation and differential diagnosis of nasolabial cyst.
Nixdorf DR, Peters E, Lung KE
J Can Dent Assoc 2003 Mar;69(3):146-9. PMID: 12622877

Clinical prediction guides

The Validation of an Innovative Method for 3D Capture and Analysis of the Nasolabial Region in Cleft Cases.
Ayoub A, Khan A, Aldhanhani A, Alnaser H, Naudi K, Ju X, Gillgrass T, Mossey P
Cleft Palate Craniofac J 2021 Jan;58(1):98-104. Epub 2020 Aug 12 doi: 10.1177/1055665620946987. PMID: 32783457Free PMC Article
Nasolabial aesthetics of patients with repaired unilateral cleft lip and palate: A comparison of three rating methods in two countries.
Nguyen VT, Nguyen T, Jagomägi T
J Craniomaxillofac Surg 2018 Aug;46(8):1385-1389. Epub 2018 May 18 doi: 10.1016/j.jcms.2018.05.029. PMID: 29861405
Judgment of Nasolabial Esthetics in Cleft Lip and Palate Is Not Influenced by Overall Facial Attractiveness.
Kocher K, Kowalski P, Kolokitha OE, Katsaros C, Fudalej PS
Cleft Palate Craniofac J 2016 May;53(3):e45-52. Epub 2015 May 1 doi: 10.1597/14-019. PMID: 25932752
Aesthetic evaluation of the nasolabial region in children with unilateral cleft lip and palate comparing expert versus nonexperience health professionals.
Paiva TS, Andre M, Paiva WS, Mattos BS
Biomed Res Int 2014;2014:460106. Epub 2014 Jul 13 doi: 10.1155/2014/460106. PMID: 25126560Free PMC Article
Anatomy research of nasolabial muscle structure in fetus with cleft lip: an iodine staining technique based on microcomputed tomography.
Wu J, Yin N
J Craniofac Surg 2014 May;25(3):1056-61. doi: 10.1097/SCS.0000000000000651. PMID: 24820718

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...