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Abnormal sacrum morphology

MedGen UID:
870793
•Concept ID:
C4025250
•
Anatomical Abnormality
Synonym: Abnormality of the sacrum
 
HPO: HP:0005107

Definition

An abnormality of the sacral bone. [from HPO]

Professional guidelines

PubMed

Spinal dural and epidural fistulas: role of cone beam CT in diagnosis and treatment.
Shapiro M, Nossek E, Sharashidze V, Tanaka M, Rutledge C, Chung C, Khawaja A, Riina H, Nelson PK, Raz E
J Neurointerv Surg 2024 May 21;16(6):615-623. doi: 10.1136/jnis-2022-019950. PMID: 37673678
Novel MNX1 mutations and genotype-phenotype analysis of patients with Currarino syndrome.
Han L, Zhang Z, Wang H, Song H, Gao Q, Yan Y, Tao R, Xiao P, Li L, Jiang Q, Li Q
Orphanet J Rare Dis 2020 Jun 22;15(1):155. doi: 10.1186/s13023-020-01442-4. PMID: 32571425Free PMC Article
Diagnostic criteria for camptocormia in Parkinson's disease: A consensus-based proposal.
Fasano A, Geroin C, Berardelli A, Bloem BR, Espay AJ, Hallett M, Lang AE, Tinazzi M
Parkinsonism Relat Disord 2018 Aug;53:53-57. Epub 2018 May 8 doi: 10.1016/j.parkreldis.2018.04.033. PMID: 29759930Free PMC Article

Recent clinical studies

Etiology

Comparative Sacral Morphology in Spondylolisthesis Patients.
Hresko MT, Deckey DG, Hinchcliff E, Kalish LA
Spine Deform 2019 Nov;7(6):945-949. doi: 10.1016/j.jspd.2019.03.008. PMID: 31732006
Relationship between spinal morphology and function and adolescent non-specific back pain: A cross-sectional study.
Feng Q, Jiang C, Zhou Y, Huang Y, Zhang M
J Back Musculoskelet Rehabil 2017;30(3):625-633. doi: 10.3233/BMR-160544. PMID: 28234252
Technology Insight: imaging of low back pain.
Finch P
Nat Clin Pract Rheumatol 2006 Oct;2(10):554-61. doi: 10.1038/ncprheum0293. PMID: 17016481
Anorectal malformations.
Peña A
Semin Pediatr Surg 1995 Feb;4(1):35-47. PMID: 7728507
Fetal sacrococcygeal teratoma.
Flake AW
Semin Pediatr Surg 1993 May;2(2):113-20. PMID: 8062028

Diagnosis

Currarino triad.
Baalaan KP, Gurunathan N
Pan Afr Med J 2022;41:143. Epub 2022 Feb 17 doi: 10.11604/pamj.2022.41.143.33419. PMID: 35519164Free PMC Article
Anorectal malformations.
Levitt MA, Peña A
Orphanet J Rare Dis 2007 Jul 26;2:33. doi: 10.1186/1750-1172-2-33. PMID: 17651510Free PMC Article
Anorectal malformations.
Peña A
Semin Pediatr Surg 1995 Feb;4(1):35-47. PMID: 7728507
Magnetic resonance imaging of the lumbar spine in people without back pain.
Jensen MC, Brant-Zawadzki MN, Obuchowski N, Modic MT, Malkasian D, Ross JS
N Engl J Med 1994 Jul 14;331(2):69-73. doi: 10.1056/NEJM199407143310201. PMID: 8208267
Translumbar amputation.
Terz JJ, Schaffner MJ, Goodkin R, Beatty JD, Razor B, Weliky A, Shimabukuro C
Cancer 1990 Jun 15;65(12):2668-75. doi: 10.1002/1097-0142(19900615)65:12<2668::aid-cncr2820651212>3.0.co;2-i. PMID: 2340466

Therapy

Congenital musculoskeletal anomalies - key radiographic findings.
Gill KG
Pediatr Radiol 2022 Apr;52(4):777-785. Epub 2021 Nov 3 doi: 10.1007/s00247-021-05200-x. PMID: 34731287
Postoperative "complications" following laparoscopic-assisted anorectoplasty: A systematic review.
Pathak M, Saxena AK
Pediatr Surg Int 2020 Nov;36(11):1299-1307. Epub 2020 Sep 26 doi: 10.1007/s00383-020-04748-3. PMID: 32980932
Sacral spinous processes: a morphologic classification and biomechanical characterization of strength.
Wang T, Fielding LC, Parikh A, Kothari M, Alamin T
Spine J 2015 Dec 1;15(12):2544-51. Epub 2015 Sep 4 doi: 10.1016/j.spinee.2015.08.058. PMID: 26343242
Acute cardiovascular effects of fetal surgery in the human.
Rychik J, Tian Z, Cohen MS, Ewing SG, Cohen D, Howell LJ, Wilson RD, Johnson MP, Hedrick HL, Flake AW, Crombleholme TM, Adzick NS
Circulation 2004 Sep 21;110(12):1549-56. Epub 2004 Sep 7 doi: 10.1161/01.CIR.0000142294.95388.C4. PMID: 15353490
Magnetic resonance imaging of the lumbar spine in people without back pain.
Jensen MC, Brant-Zawadzki MN, Obuchowski N, Modic MT, Malkasian D, Ross JS
N Engl J Med 1994 Jul 14;331(2):69-73. doi: 10.1056/NEJM199407143310201. PMID: 8208267

Prognosis

Postoperative complications and long-term outcomes in Currarino syndrome.
Sakurai T, Nakamura M, Endo N
Pediatr Surg Int 2021 Dec;37(12):1773-1781. Epub 2021 Aug 30 doi: 10.1007/s00383-021-04984-1. PMID: 34462793
Relationship between spinal morphology and function and adolescent non-specific back pain: A cross-sectional study.
Feng Q, Jiang C, Zhou Y, Huang Y, Zhang M
J Back Musculoskelet Rehabil 2017;30(3):625-633. doi: 10.3233/BMR-160544. PMID: 28234252
Anorectal malformations.
Levitt MA, Peña A
Orphanet J Rare Dis 2007 Jul 26;2:33. doi: 10.1186/1750-1172-2-33. PMID: 17651510Free PMC Article
Anorectal malformations.
Peña A
Semin Pediatr Surg 1995 Feb;4(1):35-47. PMID: 7728507
Sacrococcygeal dysgenesis association.
Duncan PA, Shapiro LR, Klein RM
Am J Med Genet 1991 Nov 1;41(2):153-61. doi: 10.1002/ajmg.1320410203. PMID: 1785625

Clinical prediction guides

Long-term outcomes in sacral agenesis.
Thomson C, Mahmood A, Yun SM, Hartley L, Botchu R, Mohmoud K, Sewell M, Mehta J
Childs Nerv Syst 2024 Jun;40(6):1791-1797. Epub 2024 Feb 27 doi: 10.1007/s00381-024-06326-7. PMID: 38411707
Evaluating the sagittal spinal and pelvic parameters in Marfan syndrome patients affected by scoliosis.
Suresh SJ, Margalit A, Sponseller PD
Spine Deform 2022 Jul;10(4):873-881. Epub 2022 Mar 11 doi: 10.1007/s43390-022-00484-x. PMID: 35277839
Anorectal malformations associated spinal cord anomalies.
Totonelli G, Morini F, Catania VD, Schingo PM, Mosiello G, Palma P, Iacobelli BD, Bagolan P
Pediatr Surg Int 2016 Aug;32(8):729-35. Epub 2016 Jul 2 doi: 10.1007/s00383-016-3914-1. PMID: 27372296
Spondylolisthesis, Sacro-Pelvic Morphology, and Orientation in Young Gymnasts.
Toueg CW, Mac-Thiong JM, Grimard G, Poitras B, Parent S, Labelle H
J Spinal Disord Tech 2015 Jul;28(6):E358-64. doi: 10.1097/BSD.0b013e3182956d62. PMID: 24201157
Anorectal malformations.
Levitt MA, Peña A
Orphanet J Rare Dis 2007 Jul 26;2:33. doi: 10.1186/1750-1172-2-33. PMID: 17651510Free PMC Article

Recent systematic reviews

Postoperative "complications" following laparoscopic-assisted anorectoplasty: A systematic review.
Pathak M, Saxena AK
Pediatr Surg Int 2020 Nov;36(11):1299-1307. Epub 2020 Sep 26 doi: 10.1007/s00383-020-04748-3. PMID: 32980932
Systematic review: sacral nerve stimulation in the treatment of constipation and fecal incontinence in children with emphasis in anorectal malformation.
Dewberry L, Trecartin A, Peña A, Pierre MS, Bischoff A
Pediatr Surg Int 2019 Sep;35(9):1009-1012. Epub 2019 Jun 29 doi: 10.1007/s00383-019-04515-z. PMID: 31256299
Anatomy and clinical significance of sacral variations: a systematic review.
Nastoulis E, Karakasi MV, Pavlidis P, Thomaidis V, Fiska A
Folia Morphol (Warsz) 2019;78(4):651-667. Epub 2019 Apr 5 doi: 10.5603/FM.a2019.0040. PMID: 30949993
Presentation and outcomes of patients with thoracic and lumbosacral spinal epidural arteriovenous fistulas: a systematic review and meta-analysis.
Byun JS, Tsang ACO, Hilditch CA, Nicholson P, Fang YB, Krings T, Pereira VM, Lanzino G, Brinjikji W
J Neurointerv Surg 2019 Jan;11(1):95-98. Epub 2018 Aug 30 doi: 10.1136/neurintsurg-2018-014203. PMID: 30166334
Long-term follow-up of functional outcome in patients with a cloacal malformation: a systematic review.
Versteegh HP, van Rooij IA, Levitt MA, Sloots CE, Wijnen RM, de Blaauw I
J Pediatr Surg 2013 Nov;48(11):2343-50. doi: 10.1016/j.jpedsurg.2013.08.027. PMID: 24210210

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