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Sclerosis of metaphyses of the upper limbs

MedGen UID:
871086
•Concept ID:
C4025551
•
Disease or Syndrome
Synonym: Increased bone density in wide portion of the upper limb bones
 
HPO: HP:0003854

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSclerosis of metaphyses of the upper limbs

Professional guidelines

PubMed

Aminohydroxy propylidene bisphosphonate (APD) treatment improves the clinical skeletal manifestations of Gaucher's disease.
Samuel R, Katz K, Papapoulos SE, Yosipovitch Z, Zaizov R, Liberman UA
Pediatrics 1994 Sep;94(3):385-9. PMID: 8065868

Recent clinical studies

Etiology

Apparent cure of a newborn with malignant osteopetrosis using prednisone therapy.
Iacobini M, Migliaccio S, Roggini M, Taranta A, Werner B, Panero A, Teti A
J Bone Miner Res 2001 Dec;16(12):2356-60. doi: 10.1359/jbmr.2001.16.12.2356. PMID: 11760852
Aminohydroxy propylidene bisphosphonate (APD) treatment improves the clinical skeletal manifestations of Gaucher's disease.
Samuel R, Katz K, Papapoulos SE, Yosipovitch Z, Zaizov R, Liberman UA
Pediatrics 1994 Sep;94(3):385-9. PMID: 8065868

Diagnosis

Apparent cure of a newborn with malignant osteopetrosis using prednisone therapy.
Iacobini M, Migliaccio S, Roggini M, Taranta A, Werner B, Panero A, Teti A
J Bone Miner Res 2001 Dec;16(12):2356-60. doi: 10.1359/jbmr.2001.16.12.2356. PMID: 11760852
Radiology of the autosomal dominant form of craniometaphyseal dysplasia.
Spiro PC, Hamersma H, Beighton P
S Afr Med J 1975 May 17;49(21):839-42. PMID: 1135718
Pyle's disease (familial metaphyseal dysplasia). A presentation of two cases and argument for its separation from craniometaphyseal dysplasia.
Gorlin RJ, Koszalka MF, Spranger J
J Bone Joint Surg Am 1970 Mar;52(2):347-54. PMID: 5440013

Therapy

Apparent cure of a newborn with malignant osteopetrosis using prednisone therapy.
Iacobini M, Migliaccio S, Roggini M, Taranta A, Werner B, Panero A, Teti A
J Bone Miner Res 2001 Dec;16(12):2356-60. doi: 10.1359/jbmr.2001.16.12.2356. PMID: 11760852
Aminohydroxy propylidene bisphosphonate (APD) treatment improves the clinical skeletal manifestations of Gaucher's disease.
Samuel R, Katz K, Papapoulos SE, Yosipovitch Z, Zaizov R, Liberman UA
Pediatrics 1994 Sep;94(3):385-9. PMID: 8065868
Chronic recurrent multifocal osteomyelitis: a follow-up study.
Jurik AG, Helmig O, Ternowitz T, Møller BN
J Pediatr Orthop 1988 Jan-Feb;8(1):49-58. doi: 10.1097/01241398-198801000-00012. PMID: 3335622
Characteristics and bisphosphonate treatment of a patient with juvenile osteoporosis.
Hoekman K, Papapoulos SE, Peters AC, Bijvoet OL
J Clin Endocrinol Metab 1985 Nov;61(5):952-6. doi: 10.1210/jcem-61-5-952. PMID: 3840174

Prognosis

Apparent cure of a newborn with malignant osteopetrosis using prednisone therapy.
Iacobini M, Migliaccio S, Roggini M, Taranta A, Werner B, Panero A, Teti A
J Bone Miner Res 2001 Dec;16(12):2356-60. doi: 10.1359/jbmr.2001.16.12.2356. PMID: 11760852
Aminohydroxy propylidene bisphosphonate (APD) treatment improves the clinical skeletal manifestations of Gaucher's disease.
Samuel R, Katz K, Papapoulos SE, Yosipovitch Z, Zaizov R, Liberman UA
Pediatrics 1994 Sep;94(3):385-9. PMID: 8065868
Chronic recurrent multifocal osteomyelitis: a follow-up study.
Jurik AG, Helmig O, Ternowitz T, Møller BN
J Pediatr Orthop 1988 Jan-Feb;8(1):49-58. doi: 10.1097/01241398-198801000-00012. PMID: 3335622
Radiology of the autosomal dominant form of craniometaphyseal dysplasia.
Spiro PC, Hamersma H, Beighton P
S Afr Med J 1975 May 17;49(21):839-42. PMID: 1135718

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