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Small epiphyses of the upper limbs

MedGen UID:
871091
•Concept ID:
C4025556
•
Anatomical Abnormality
Synonym: Small end part of upper limb bones
 
HPO: HP:0003844

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSmall epiphyses of the upper limbs

Professional guidelines

PubMed

Physeal and periphyseal injuries of the hand. Patterns of injury and results of treatment.
Fischer MD, McElfresh EC
Hand Clin 1994 May;10(2):287-301. PMID: 8040207
The conservative treatment of the fractures and dislocations of the extremities in children.
Tosovský V, Stryhal F
Acta Univ Carol Med Monogr 1986;111:1-145. PMID: 2886016

Recent clinical studies

Etiology

Radiographic Characteristics of the Hand in Apert Syndrome.
Kracoff SL
J Hand Surg Asian Pac Vol 2020 Mar;25(1):82-86. doi: 10.1142/S2424835520500113. PMID: 32000596
Abnormalities of the axial and proximal appendicular skeleton in adults with Laron syndrome (growth hormone insensitivity).
Kornreich L, Konen O, Schwarz M, Siegel Y, Horev G, Hershkovitz I, Laron Z
Skeletal Radiol 2008 Feb;37(2):153-60. Epub 2007 Nov 9 doi: 10.1007/s00256-007-0402-7. PMID: 17992526
Physeal and periphyseal injuries of the hand. Patterns of injury and results of treatment.
Fischer MD, McElfresh EC
Hand Clin 1994 May;10(2):287-301. PMID: 8040207
Avascular necrosis and vascular anatomy of the metacarpals.
Wright TC, Dell PC
J Hand Surg Am 1991 May;16(3):540-4. doi: 10.1016/0363-5023(91)90029-b. PMID: 1861041
Blood-borne spread of a benign giant cell tumor from the radius to the soft tissue of the hand.
Joly MA, Vázquez JJ, Martinez A, Guillen FJ
Cancer 1984 Dec 1;54(11):2564-7. doi: 10.1002/1097-0142(19841201)54:11<2564::aid-cncr2820541143>3.0.co;2-9. PMID: 6498747

Diagnosis

Nonvascularized Toe Joint Transfers to the Hand in Young Children: Technique Revisited.
Trost JG, Kaufman M, Netscher DT
Hand (N Y) 2022 Jul;17(4):676-683. Epub 2020 Aug 11 doi: 10.1177/1558944720948243. PMID: 32779490Free PMC Article
Upper and lower limb length equalization: diagnosis, limb lengthening and curtailment, epiphysiodesis.
Burnei G, Vlad C, Gavriliu S, Georgescu I, Hodorogea D, Pârvan A, Burnei C, El Nayef T, Drăghici I
Rom J Intern Med 2012 Jan-Mar;50(1):43-59. PMID: 22788093
Abnormalities of the axial and proximal appendicular skeleton in adults with Laron syndrome (growth hormone insensitivity).
Kornreich L, Konen O, Schwarz M, Siegel Y, Horev G, Hershkovitz I, Laron Z
Skeletal Radiol 2008 Feb;37(2):153-60. Epub 2007 Nov 9 doi: 10.1007/s00256-007-0402-7. PMID: 17992526
Ultrasound in the diagnosis of fractures in children.
Hübner U, Schlicht W, Outzen S, Barthel M, Halsband H
J Bone Joint Surg Br 2000 Nov;82(8):1170-3. doi: 10.1302/0301-620x.82b8.10087. PMID: 11132281
Epiphyseal injuries in the small joints of the hand.
Torre BA
Hand Clin 1988 Feb;4(1):113-21. PMID: 3277975

Therapy

Radiographic Characteristics of the Hand in Apert Syndrome.
Kracoff SL
J Hand Surg Asian Pac Vol 2020 Mar;25(1):82-86. doi: 10.1142/S2424835520500113. PMID: 32000596
Rough endoplasmic reticulum abnormalities in a patient with spondyloepimetaphyseal dysplasia with scoliosis, joint laxity, and finger deformities.
Shapiro F, Mulhern H, Weis MA, Eyre D
Ultrastruct Pathol 2006 Sep-Oct;30(5):393-400. doi: 10.1080/01913120600967004. PMID: 17090519
Estimation of various mechanical characteristics of human bones using dual energy X-ray absorptiometry: methodology and precision.
Sievänen H, Kannus P, Nieminen V, Heinonen A, Oja P, Vuori I
Bone 1996 Jan;18(1 Suppl):17S-27S. doi: 10.1016/8756-3282(95)00376-2. PMID: 8717544
Congenital malformations associated with the administration of oral anticoagulants during pregnancy.
Pettifor JM, Benson R
J Pediatr 1975 Mar;86(3):459-62. doi: 10.1016/s0022-3476(75)80986-3. PMID: 1113236

Prognosis

Beyond Human Perception: Sexual Dimorphism in Hand and Wrist Radiographs Is Discernible by a Deep Learning Model.
Yune S, Lee H, Kim M, Tajmir SH, Gee MS, Do S
J Digit Imaging 2019 Aug;32(4):665-671. doi: 10.1007/s10278-018-0148-x. PMID: 30478479Free PMC Article
Thumb Ossification Composite Index (TOCI) for Predicting Peripubertal Skeletal Maturity and Peak Height Velocity in Idiopathic Scoliosis: A Validation Study of Premenarchal Girls with Adolescent Idiopathic Scoliosis Followed Longitudinally Until Skeletal Maturity.
Hung ALH, Chau WW, Shi B, Chow SK, Yu FYP, Lam TP, Ng BKW, Qiu Y, Cheng JCY
J Bone Joint Surg Am 2017 Sep 6;99(17):1438-1446. doi: 10.2106/JBJS.16.01078. PMID: 28872525Free PMC Article
Severe neurologic manifestations from cervical spine instability in spondylo-megaepiphyseal-metaphyseal dysplasia.
Simon M, Campos-Xavier AB, Mittaz-Crettol L, Valadares ER, Carvalho D, Speck-Martins CE, Nampoothiri S, Alanay Y, Mihci E, van Bever Y, Garcia-Segarra N, Cavalcanti D, Mortier G, Bonafé L, Superti-Furga A
Am J Med Genet C Semin Med Genet 2012 Aug 15;160C(3):230-7. Epub 2012 Jul 12 doi: 10.1002/ajmg.c.31339. PMID: 22791571
A description of the Omo I postcranial skeleton, including newly discovered fossils.
Pearson OM, Royer DF, Grine FE, Fleagle JG
J Hum Evol 2008 Sep;55(3):421-37. Epub 2008 Aug 8 doi: 10.1016/j.jhevol.2008.05.018. PMID: 18691733
Blood-borne spread of a benign giant cell tumor from the radius to the soft tissue of the hand.
Joly MA, Vázquez JJ, Martinez A, Guillen FJ
Cancer 1984 Dec 1;54(11):2564-7. doi: 10.1002/1097-0142(19841201)54:11<2564::aid-cncr2820541143>3.0.co;2-9. PMID: 6498747

Clinical prediction guides

Nonvascularized Toe Joint Transfers to the Hand in Young Children: Technique Revisited.
Trost JG, Kaufman M, Netscher DT
Hand (N Y) 2022 Jul;17(4):676-683. Epub 2020 Aug 11 doi: 10.1177/1558944720948243. PMID: 32779490Free PMC Article
A new form of severe spondyloepimetaphyseal dysplasia: clinical and radiological characterization.
Isidor B, Geffroy L, de Courtivron B, Le Caignec C, Thiel CT, Mortier G, Cormier-Daire V, David A, Toutain A
Am J Med Genet A 2013 Oct;161A(10):2645-51. Epub 2013 Aug 16 doi: 10.1002/ajmg.a.36132. PMID: 23956136
Severe neurologic manifestations from cervical spine instability in spondylo-megaepiphyseal-metaphyseal dysplasia.
Simon M, Campos-Xavier AB, Mittaz-Crettol L, Valadares ER, Carvalho D, Speck-Martins CE, Nampoothiri S, Alanay Y, Mihci E, van Bever Y, Garcia-Segarra N, Cavalcanti D, Mortier G, Bonafé L, Superti-Furga A
Am J Med Genet C Semin Med Genet 2012 Aug 15;160C(3):230-7. Epub 2012 Jul 12 doi: 10.1002/ajmg.c.31339. PMID: 22791571
Metacarpal and phalangeal lengthening by callus distraction.
Houshian S, Ipsen T
J Hand Surg Br 2001 Feb;26(1):13-6. doi: 10.1054/jhsb.2000.0478. PMID: 11162007
Macrodystrophia lipomatosa: radiographic observations.
Gupta SK, Sharma OP, Sharma SV, Sood B, Gupta S
Br J Radiol 1992 Sep;65(777):769-73. doi: 10.1259/0007-1285-65-777-769. PMID: 1393412

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