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Skin fibroepithelial basal cell carcinoma

MedGen UID:
87529
•Concept ID:
C0346013
•
Neoplastic Process
Synonyms: Basal cell carcinoma, fibroepithelial; Fibroepithelial basal cell carcinoma; Fibroepithelial Basal Cell Carcinoma; fibroepithelial basal cell carcinoma; Fibroepithelial basal cell carcinoma, Pinkus type; Fibroepithelioma; Fibroepithelioma of Pinkus; fibroepithelioma of Pinkus; Fibroepithelioma of Pinkus type; fibroepithelioma of Pinkus type; Pinkus tumor; Pinkus Tumor; Pinkus tumour; Skin Fibroepithelial Basal Cell Carcinoma; skin fibroepithelial basal cell carcinoma
SNOMED CT: Fibroepithelial basal cell carcinoma (43369006); Pinkus tumor (43369006); Fibroepithelioma (43369006); Fibroepithelioma of Pinkus type (43369006); Fibroepithelial basal cell carcinoma, Pinkus type (43369006); Pinkus tumor (254703005); Fibroepithelioma of Pinkus (254703005); Basal cell carcinoma, fibroepithelial (43369006)
 
Monarch Initiative: MONDO:0002948

Definition

A variant of basal cell carcinoma presenting as an elevated or erythematous nodular lesion usually in the back. Morphologically, it is characterized by the presence of cords of basaloid cells extending from the epidermis into the dermis, creating a fenestrating pattern. It follows an indolent course. [from NCI]

Professional guidelines

PubMed

Diagnosis and Management of Basal Cell Carcinoma.
Tanese K
Curr Treat Options Oncol 2019 Feb 11;20(2):13. doi: 10.1007/s11864-019-0610-0. PMID: 30741348
Dermoscopic criteria and basal cell carcinoma.
Puig S, Cecilia N, Malvehy J
G Ital Dermatol Venereol 2012 Apr;147(2):135-40. PMID: 22481576
Imiquimod 5% cream: a new treatment option for basal cell carcinoma.
Salasche S
Int J Dermatol 2002 May;41 Suppl 1:16-20. doi: 10.1111/j.1365-4632.2002.00020.x. PMID: 12087814

Recent clinical studies

Etiology

Diagnosis and Management of Basal Cell Carcinoma.
Tanese K
Curr Treat Options Oncol 2019 Feb 11;20(2):13. doi: 10.1007/s11864-019-0610-0. PMID: 30741348
Basal cell carcinoma: clinical and pathological features.
Di Stefani A, Chimenti S
G Ital Dermatol Venereol 2015 Aug;150(4):385-91. Epub 2015 Jun 23 PMID: 26099353
Basal cell and squamous cell carcinomas. Clinico-histological features.
Annessi G, Baliva G
Ann Ist Super Sanita 1996;32(1):29-36. PMID: 8804183
Basal cell epithelioma (carcinoma) in children and teenagers.
Rahbari H, Mehregan AH
Cancer 1982 Jan 15;49(2):350-3. doi: 10.1002/1097-0142(19820115)49:2<350::aid-cncr2820490223>3.0.co;2-y. PMID: 7053833
Cutaneous basal cell carcinoma of vulva.
Cruz-Jimenez PR, Abell MR
Cancer 1975 Nov;36(5):1860-8. doi: 10.1002/1097-0142(197511)36:5<1860::aid-cncr2820360543>3.0.co;2-w. PMID: 1192371

Diagnosis

Have Skin Biopsy Results in Adults Been Affected in the COVID-19 Pandemic?
Çölgeçen E, Gökçek GE, Şahin S
Acta Dermatovenerol Croat 2022 Jul;30(1):40-48. PMID: 36153718
Diagnosis and Management of Basal Cell Carcinoma.
Tanese K
Curr Treat Options Oncol 2019 Feb 11;20(2):13. doi: 10.1007/s11864-019-0610-0. PMID: 30741348
Fibroepithelioma of Pinkus.
Bartos V, Pokorny D, Zacharova O, Kullova M, Adamicova K, Pec M
Bratisl Lek Listy 2012;113(10):624-7. doi: 10.4149/bll_2012_142. PMID: 23094905
Dermoscopic criteria and basal cell carcinoma.
Puig S, Cecilia N, Malvehy J
G Ital Dermatol Venereol 2012 Apr;147(2):135-40. PMID: 22481576
Basal cell carcinoma with fibroepithelioma-like histology in a healthy child: report and review of the literature.
Scalvenzi M, Francia MG, Falleti J, Balato A
Pediatr Dermatol 2008 May-Jun;25(3):359-63. doi: 10.1111/j.1525-1470.2008.00683.x. PMID: 18577044

Therapy

Diagnosis and Management of Basal Cell Carcinoma.
Tanese K
Curr Treat Options Oncol 2019 Feb 11;20(2):13. doi: 10.1007/s11864-019-0610-0. PMID: 30741348
Imiquimod 5% cream: a new treatment option for basal cell carcinoma.
Salasche S
Int J Dermatol 2002 May;41 Suppl 1:16-20. doi: 10.1111/j.1365-4632.2002.00020.x. PMID: 12087814

Prognosis

Morphologic, Immunohistochemical, and Molecular Distinction Between Fibroepithelioma of Pinkus and "Fenestrated" Basal Cell Carcinoma.
Russell-Goldman E, Lindeman NI, Laga AC, Hanna J
Am J Dermatopathol 2020 Jul;42(7):513-520. doi: 10.1097/DAD.0000000000001563. PMID: 31693503
Diagnosis and Management of Basal Cell Carcinoma.
Tanese K
Curr Treat Options Oncol 2019 Feb 11;20(2):13. doi: 10.1007/s11864-019-0610-0. PMID: 30741348
Basal cell carcinoma: clinical and pathological features.
Di Stefani A, Chimenti S
G Ital Dermatol Venereol 2015 Aug;150(4):385-91. Epub 2015 Jun 23 PMID: 26099353
Fibroepithelioma of Pinkus.
Bartos V, Pokorny D, Zacharova O, Kullova M, Adamicova K, Pec M
Bratisl Lek Listy 2012;113(10):624-7. doi: 10.4149/bll_2012_142. PMID: 23094905
Cutaneous basal cell carcinoma of vulva.
Cruz-Jimenez PR, Abell MR
Cancer 1975 Nov;36(5):1860-8. doi: 10.1002/1097-0142(197511)36:5<1860::aid-cncr2820360543>3.0.co;2-w. PMID: 1192371

Clinical prediction guides

Have Skin Biopsy Results in Adults Been Affected in the COVID-19 Pandemic?
Çölgeçen E, Gökçek GE, Şahin S
Acta Dermatovenerol Croat 2022 Jul;30(1):40-48. PMID: 36153718
Diagnostic concordance rates in the subtyping of basal cell carcinoma by different dermatopathologists.
Nedved D, Tonkovic-Capin V, Hunt E, Zaidi N, Kucenic MJ, Graves JJ, Fraga GR
J Cutan Pathol 2014 Jan;41(1):9-13. Epub 2013 Nov 14 doi: 10.1111/cup.12256. PMID: 24152016
Fibroepithelioma of Pinkus: case reports and review of the literature.
Reggiani C, Zalaudek I, Piana S, Longo C, Argenziano G, Lallas A, Pellacani G, Moscarella E
Dermatology 2013;226(3):207-11. Epub 2013 May 25 doi: 10.1159/000348707. PMID: 23711617
Fibroepithelioma of Pinkus.
Bartos V, Pokorny D, Zacharova O, Kullova M, Adamicova K, Pec M
Bratisl Lek Listy 2012;113(10):624-7. doi: 10.4149/bll_2012_142. PMID: 23094905
Basal cell carcinoma with fibroepithelioma-like histology in a healthy child: report and review of the literature.
Scalvenzi M, Francia MG, Falleti J, Balato A
Pediatr Dermatol 2008 May-Jun;25(3):359-63. doi: 10.1111/j.1525-1470.2008.00683.x. PMID: 18577044

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