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Central Nervous System Involvement

MedGen UID:
884503
•Concept ID:
C4050309
•
Finding
Synonym: Central nervous system involvement

Definition

A finding indicating the involvement of the central nervous system by a malignant neoplasm. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral Nervous System Involvement

Professional guidelines

PubMed

Central Nervous System Involvement in Adults with Acute Leukemia: Diagnosis, Prevention, and Management.
Paul S, Short NJ
Curr Oncol Rep 2022 Apr;24(4):427-436. Epub 2022 Feb 10 doi: 10.1007/s11912-022-01220-4. PMID: 35141858
The treatment of Burkitt lymphoma in adults.
Crombie J, LaCasce A
Blood 2021 Feb 11;137(6):743-750. doi: 10.1182/blood.2019004099. PMID: 33171490
Advances in diagnosis and management of Pompe disease.
Davison JE
J Mother Child 2020 Oct 2;24(2):3-8. doi: 10.34763/jmotherandchild.20202402si.2001.000002. PMID: 33554498Free PMC Article

Recent clinical studies

Etiology

How I treat diffuse large B-cell lymphoma.
Melchardt T, Egle A, Greil R
ESMO Open 2023 Feb;8(1):100750. Epub 2023 Jan 10 doi: 10.1016/j.esmoop.2022.100750. PMID: 36634531Free PMC Article
Central nervous system involvement in individuals with RASopathies.
Weaver KN, Gripp KW
Am J Med Genet C Semin Med Genet 2022 Dec;190(4):494-500. Epub 2022 Dec 1 doi: 10.1002/ajmg.c.32023. PMID: 36454176
Neurobrucellosis: Brief Review.
Bouferraa Y, Bou Zerdan M, Hamouche R, Azar E, Afif C, Jabbour R
Neurologist 2021 Nov 4;26(6):248-252. doi: 10.1097/NRL.0000000000000348. PMID: 34734902
Behçet syndrome.
Yazici Y, Hatemi G, Bodaghi B, Cheon JH, Suzuki N, Ambrose N, Yazici H
Nat Rev Dis Primers 2021 Sep 16;7(1):67. doi: 10.1038/s41572-021-00301-1. PMID: 34531393
Imaging of Tumor Syndromes.
Batchala PP, Eluvathingal Muttikkal TJ, Mukherjee S
Radiol Clin North Am 2021 May;59(3):471-500. doi: 10.1016/j.rcl.2021.01.009. PMID: 33926690

Diagnosis

Neurobrucellosis: Brief Review.
Bouferraa Y, Bou Zerdan M, Hamouche R, Azar E, Afif C, Jabbour R
Neurologist 2021 Nov 4;26(6):248-252. doi: 10.1097/NRL.0000000000000348. PMID: 34734902
Imaging of Tumor Syndromes.
Batchala PP, Eluvathingal Muttikkal TJ, Mukherjee S
Radiol Clin North Am 2021 May;59(3):471-500. doi: 10.1016/j.rcl.2021.01.009. PMID: 33926690
Pure Autonomic Failure.
Coon EA, Singer W, Low PA
Mayo Clin Proc 2019 Oct;94(10):2087-2098. Epub 2019 Sep 9 doi: 10.1016/j.mayocp.2019.03.009. PMID: 31515103Free PMC Article
Polyarteritis Nodosa Neurologic Manifestations.
de Boysson H, Guillevin L
Neurol Clin 2019 May;37(2):345-357. Epub 2019 Mar 16 doi: 10.1016/j.ncl.2019.01.007. PMID: 30952413
Bickerstaff's encephalitis.
Horton E, Krishnamoorthy S, Reynolds L
BMJ Case Rep 2014 Jul 30;2014 doi: 10.1136/bcr-2014-205336. PMID: 25080547Free PMC Article

Therapy

How I treat diffuse large B-cell lymphoma.
Melchardt T, Egle A, Greil R
ESMO Open 2023 Feb;8(1):100750. Epub 2023 Jan 10 doi: 10.1016/j.esmoop.2022.100750. PMID: 36634531Free PMC Article
Trastuzumab deruxtecan in patients with central nervous system involvement from HER2-positive breast cancer: The DEBBRAH trial.
Pérez-García JM, Vaz Batista M, Cortez P, Ruiz-Borrego M, Cejalvo JM, de la Haba-Rodriguez J, Garrigós L, Racca F, Servitja S, Blanch S, Gion M, Nave M, Fernández-Abad M, Martinez-Bueno A, Llombart-Cussac A, Sampayo-Cordero M, Malfettone A, Cortés J, Braga S
Neuro Oncol 2023 Jan 5;25(1):157-166. doi: 10.1093/neuonc/noac144. PMID: 35639825Free PMC Article
The treatment of Burkitt lymphoma in adults.
Crombie J, LaCasce A
Blood 2021 Feb 11;137(6):743-750. doi: 10.1182/blood.2019004099. PMID: 33171490
Henoch-Schönlein Purpura (IgA Vasculitis): Rapid Evidence Review.
Reamy BV, Servey JT, Williams PM
Am Fam Physician 2020 Aug 15;102(4):229-233. PMID: 32803924
Erdheim-Chester disease.
Haroche J, Arnaud L, Amoura Z
Curr Opin Rheumatol 2012 Jan;24(1):53-9. doi: 10.1097/BOR.0b013e32834d861d. PMID: 22089098

Prognosis

How I treat diffuse large B-cell lymphoma.
Melchardt T, Egle A, Greil R
ESMO Open 2023 Feb;8(1):100750. Epub 2023 Jan 10 doi: 10.1016/j.esmoop.2022.100750. PMID: 36634531Free PMC Article
Age-related immunosenescence in Behçet's disease.
Üsküdar Cansu D, Korkmaz C
Rheumatol Int 2022 Sep;42(9):1513-1522. Epub 2022 May 20 doi: 10.1007/s00296-022-05144-x. PMID: 35593976
Neurobrucellosis: Brief Review.
Bouferraa Y, Bou Zerdan M, Hamouche R, Azar E, Afif C, Jabbour R
Neurologist 2021 Nov 4;26(6):248-252. doi: 10.1097/NRL.0000000000000348. PMID: 34734902
Polyarteritis Nodosa Neurologic Manifestations.
de Boysson H, Guillevin L
Neurol Clin 2019 May;37(2):345-357. Epub 2019 Mar 16 doi: 10.1016/j.ncl.2019.01.007. PMID: 30952413
Erdheim-Chester disease.
Haroche J, Arnaud L, Amoura Z
Curr Opin Rheumatol 2012 Jan;24(1):53-9. doi: 10.1097/BOR.0b013e32834d861d. PMID: 22089098

Clinical prediction guides

Neuroimaging in tuberous sclerosis complex.
Russo C, Nastro A, Cicala D, De Liso M, Covelli EM, Cinalli G
Childs Nerv Syst 2020 Oct;36(10):2497-2509. Epub 2020 Jun 9 doi: 10.1007/s00381-020-04705-4. PMID: 32519125
Erdheim-Chester disease.
Haroche J, Cohen-Aubart F, Amoura Z
Blood 2020 Apr 16;135(16):1311-1318. doi: 10.1182/blood.2019002766. PMID: 32107533
Erdheim-Chester disease.
Haroche J, Arnaud L, Cohen-Aubart F, Hervier B, Charlotte F, Emile JF, Amoura Z
Curr Rheumatol Rep 2014 Apr;16(4):412. doi: 10.1007/s11926-014-0412-0. PMID: 24532298
Erdheim-Chester disease.
Haroche J, Arnaud L, Amoura Z
Curr Opin Rheumatol 2012 Jan;24(1):53-9. doi: 10.1097/BOR.0b013e32834d861d. PMID: 22089098
Central nervous system lymphoma.
Lister A, Abrey LE, Sandlund JT
Hematology Am Soc Hematol Educ Program 2002:283-96. doi: 10.1182/asheducation-2002.1.283. PMID: 12446428

Recent systematic reviews

Targeted therapy for advanced anaplastic lymphoma kinase (<I>ALK</I>)-rearranged non-small cell lung cancer.
Cameron LB, Hitchen N, Chandran E, Morris T, Manser R, Solomon BJ, Jordan V
Cochrane Database Syst Rev 2022 Jan 7;1(1):CD013453. doi: 10.1002/14651858.CD013453.pub2. PMID: 34994987Free PMC Article
CNS and PNS manifestation in immune checkpoint inhibitors: A systematic review.
Khan E, Shrestha AK, Elkhooly M, Wilson H, Ebbert M, Srivastava S, Wen S, Rollins S, Sriwastava S
J Neurol Sci 2022 Jan 15;432:120089. Epub 2021 Dec 16 doi: 10.1016/j.jns.2021.120089. PMID: 34942546
Central nervous system involvement in eosinophilic granulomatosis with polyangiitis (Churg-Strauss): Report of 26 patients and review of the literature.
André R, Cottin V, Saraux JL, Blaison G, Bienvenu B, Cathebras P, Dhote R, Foucher A, Gil H, Lapoirie J, Launay D, Loustau V, Maurier F, Pertuiset E, Zénone T, Seebach J, Costedoat-Chalumeau N, Puéchal X, Mouthon L, Guillevin L, Terrier B; French Vasculitis Study Group (FVSG)
Autoimmun Rev 2017 Sep;16(9):963-969. Epub 2017 Jul 12 doi: 10.1016/j.autrev.2017.07.007. PMID: 28709761
Central nervous system involvement in diffuse large B-cell lymphoma: an analysis of risks and prevention strategies in the post-rituximab era.
Fletcher CD, Kahl BS
Leuk Lymphoma 2014 Oct;55(10):2228-40. Epub 2014 Feb 24 doi: 10.3109/10428194.2013.869326. PMID: 24286262
Central nervous system manifestations of neonatal lupus: a systematic review.
Chen CC, Lin KL, Chen CL, Wong AM, Huang JL
Lupus 2013 Dec;22(14):1484-8. Epub 2013 Oct 18 doi: 10.1177/0961203313509294. PMID: 24142583

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