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Germinomatous germ cell tumor

MedGen UID:
888719
•Concept ID:
C4054897
•
Neoplastic Process
Synonyms: Germinomatous Germ Cell Tumor; germinomatous germ cell tumor
 
Monarch Initiative: MONDO:0020580

Definition

A term that refers to germinoma, seminoma, or dysgerminoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGerminomatous germ cell tumor

Professional guidelines

PubMed

Outcomes of intracranial non-germinomatous germ cell tumors: a retrospective Asian multinational study on treatment strategies and prognostic factors.
Hong KT, Han JW, Fuji H, Byun HK, Koh KN, Wong RX, Lee HL, Yoon HI, Lee JH, Phi JH, Kim SK, Kim DS, Lyu CJ, Choi JY, Kang HJ, Chen YW, Lee YY, Im HJ, Ra YS, Do Ahn S, Low SYY, Looi WS, Park HJ, Suh YG, Suh CO, Wang KC, Tan EEK, Wong TT, Kim JY
J Neurooncol 2022 Oct;160(1):41-53. Epub 2022 Aug 31 doi: 10.1007/s11060-022-04100-w. PMID: 36045266
EANO, SNO and Euracan consensus review on the current management and future development of intracranial germ cell tumors in adolescents and young adults.
Frappaz D, Dhall G, Murray MJ, Goldman S, Faure Conter C, Allen J, Kortmann RD, Haas-Kogen D, Morana G, Finlay J, Nicholson JC, Bartels U, Souweidane M, Schönberger S, Vasiljevic A, Robertson P, Albanese A, Alapetite C, Czech T, Lau CC, Wen P, Schiff D, Shaw D, Calaminus G, Bouffet E
Neuro Oncol 2022 Apr 1;24(4):516-527. doi: 10.1093/neuonc/noab252. PMID: 34724065Free PMC Article
Treatment and survival of primary intracranial germ cell tumors: a population-based study using SEER database.
Denyer S, Bhimani AD, Patil SN, Mudreac A, Behbahani M, Mehta AI
J Cancer Res Clin Oncol 2020 Mar;146(3):671-685. Epub 2019 Nov 19 doi: 10.1007/s00432-019-03088-7. PMID: 31745701

Recent clinical studies

Etiology

RARE INTRACRANIAL MULTIFOCAL NON-GERMINOMATOUS GERM CELL TUMOR IN AN 18-YEAR-OLD MALE: A CASE REPORT.
Sesar N, Splavski B, Gamulin M, Rotim K
Acta Clin Croat 2023 Apr;62(1):234-240. doi: 10.20471/acc.2023.62.01.28. PMID: 38304368Free PMC Article
Primary Intracranial Germ Cell Tumors: A Study with an Integrated Clinicopathological Approach.
Sahay A, Epari S, Chinnaswamy G, Chatterjee A, Goda JS, Patil V, Moyiadi A, Shetty P, Singh V, Sahu A, Choudhary A, Janu A, Gupta T
Neurol India 2023 May-Jun;71(3):500-508. doi: 10.4103/0028-3886.378644. PMID: 37322747
Outcomes of intracranial non-germinomatous germ cell tumors: a retrospective Asian multinational study on treatment strategies and prognostic factors.
Hong KT, Han JW, Fuji H, Byun HK, Koh KN, Wong RX, Lee HL, Yoon HI, Lee JH, Phi JH, Kim SK, Kim DS, Lyu CJ, Choi JY, Kang HJ, Chen YW, Lee YY, Im HJ, Ra YS, Do Ahn S, Low SYY, Looi WS, Park HJ, Suh YG, Suh CO, Wang KC, Tan EEK, Wong TT, Kim JY
J Neurooncol 2022 Oct;160(1):41-53. Epub 2022 Aug 31 doi: 10.1007/s11060-022-04100-w. PMID: 36045266
EANO, SNO and Euracan consensus review on the current management and future development of intracranial germ cell tumors in adolescents and young adults.
Frappaz D, Dhall G, Murray MJ, Goldman S, Faure Conter C, Allen J, Kortmann RD, Haas-Kogen D, Morana G, Finlay J, Nicholson JC, Bartels U, Souweidane M, Schönberger S, Vasiljevic A, Robertson P, Albanese A, Alapetite C, Czech T, Lau CC, Wen P, Schiff D, Shaw D, Calaminus G, Bouffet E
Neuro Oncol 2022 Apr 1;24(4):516-527. doi: 10.1093/neuonc/noab252. PMID: 34724065Free PMC Article
Detecting non-germinomatous germ cell tumor component by arterial spin labeling perfusion-weighted MR imaging in central nervous system germ cell tumor.
Takano M, Kinoshita Y, Sugiyama K, Kolakshyapati M, Takayasu T, Yonezawa U, Taguchi A, Akiyama Y, Amatya VJ, Takeshima Y, Kurisu K, Yamasaki F
Eur J Radiol 2021 Mar;136:109523. Epub 2021 Jan 7 doi: 10.1016/j.ejrad.2021.109523. PMID: 33460957

Diagnosis

RARE INTRACRANIAL MULTIFOCAL NON-GERMINOMATOUS GERM CELL TUMOR IN AN 18-YEAR-OLD MALE: A CASE REPORT.
Sesar N, Splavski B, Gamulin M, Rotim K
Acta Clin Croat 2023 Apr;62(1):234-240. doi: 10.20471/acc.2023.62.01.28. PMID: 38304368Free PMC Article
Primary Intracranial Germ Cell Tumors: A Study with an Integrated Clinicopathological Approach.
Sahay A, Epari S, Chinnaswamy G, Chatterjee A, Goda JS, Patil V, Moyiadi A, Shetty P, Singh V, Sahu A, Choudhary A, Janu A, Gupta T
Neurol India 2023 May-Jun;71(3):500-508. doi: 10.4103/0028-3886.378644. PMID: 37322747
Outcomes of intracranial non-germinomatous germ cell tumors: a retrospective Asian multinational study on treatment strategies and prognostic factors.
Hong KT, Han JW, Fuji H, Byun HK, Koh KN, Wong RX, Lee HL, Yoon HI, Lee JH, Phi JH, Kim SK, Kim DS, Lyu CJ, Choi JY, Kang HJ, Chen YW, Lee YY, Im HJ, Ra YS, Do Ahn S, Low SYY, Looi WS, Park HJ, Suh YG, Suh CO, Wang KC, Tan EEK, Wong TT, Kim JY
J Neurooncol 2022 Oct;160(1):41-53. Epub 2022 Aug 31 doi: 10.1007/s11060-022-04100-w. PMID: 36045266
EANO, SNO and Euracan consensus review on the current management and future development of intracranial germ cell tumors in adolescents and young adults.
Frappaz D, Dhall G, Murray MJ, Goldman S, Faure Conter C, Allen J, Kortmann RD, Haas-Kogen D, Morana G, Finlay J, Nicholson JC, Bartels U, Souweidane M, Schönberger S, Vasiljevic A, Robertson P, Albanese A, Alapetite C, Czech T, Lau CC, Wen P, Schiff D, Shaw D, Calaminus G, Bouffet E
Neuro Oncol 2022 Apr 1;24(4):516-527. doi: 10.1093/neuonc/noab252. PMID: 34724065Free PMC Article
Detecting non-germinomatous germ cell tumor component by arterial spin labeling perfusion-weighted MR imaging in central nervous system germ cell tumor.
Takano M, Kinoshita Y, Sugiyama K, Kolakshyapati M, Takayasu T, Yonezawa U, Taguchi A, Akiyama Y, Amatya VJ, Takeshima Y, Kurisu K, Yamasaki F
Eur J Radiol 2021 Mar;136:109523. Epub 2021 Jan 7 doi: 10.1016/j.ejrad.2021.109523. PMID: 33460957

Therapy

RARE INTRACRANIAL MULTIFOCAL NON-GERMINOMATOUS GERM CELL TUMOR IN AN 18-YEAR-OLD MALE: A CASE REPORT.
Sesar N, Splavski B, Gamulin M, Rotim K
Acta Clin Croat 2023 Apr;62(1):234-240. doi: 10.20471/acc.2023.62.01.28. PMID: 38304368Free PMC Article
Re-induction chemotherapy regimens in patients with recurrent central nervous system mixed malignant germ cell tumors.
Abu Arja MH, Stanek JR, Finlay JL, AbdelBaki MS
Childs Nerv Syst 2018 Nov;34(11):2179-2186. Epub 2018 Aug 3 doi: 10.1007/s00381-018-3940-5. PMID: 30076436

Prognosis

Pediatric sellar teratoma - Case report and review of the literature.
Kürner K, Greuter L, Roethlisberger M, Brand Y, Frank S, Guzman R, Soleman J
Childs Nerv Syst 2024 Apr;40(4):1259-1270. Epub 2024 Jan 26 doi: 10.1007/s00381-024-06296-w. PMID: 38276973Free PMC Article
RARE INTRACRANIAL MULTIFOCAL NON-GERMINOMATOUS GERM CELL TUMOR IN AN 18-YEAR-OLD MALE: A CASE REPORT.
Sesar N, Splavski B, Gamulin M, Rotim K
Acta Clin Croat 2023 Apr;62(1):234-240. doi: 10.20471/acc.2023.62.01.28. PMID: 38304368Free PMC Article
Primary Intracranial Germ Cell Tumors: A Study with an Integrated Clinicopathological Approach.
Sahay A, Epari S, Chinnaswamy G, Chatterjee A, Goda JS, Patil V, Moyiadi A, Shetty P, Singh V, Sahu A, Choudhary A, Janu A, Gupta T
Neurol India 2023 May-Jun;71(3):500-508. doi: 10.4103/0028-3886.378644. PMID: 37322747
Outcomes of intracranial non-germinomatous germ cell tumors: a retrospective Asian multinational study on treatment strategies and prognostic factors.
Hong KT, Han JW, Fuji H, Byun HK, Koh KN, Wong RX, Lee HL, Yoon HI, Lee JH, Phi JH, Kim SK, Kim DS, Lyu CJ, Choi JY, Kang HJ, Chen YW, Lee YY, Im HJ, Ra YS, Do Ahn S, Low SYY, Looi WS, Park HJ, Suh YG, Suh CO, Wang KC, Tan EEK, Wong TT, Kim JY
J Neurooncol 2022 Oct;160(1):41-53. Epub 2022 Aug 31 doi: 10.1007/s11060-022-04100-w. PMID: 36045266
Re-induction chemotherapy regimens in patients with recurrent central nervous system mixed malignant germ cell tumors.
Abu Arja MH, Stanek JR, Finlay JL, AbdelBaki MS
Childs Nerv Syst 2018 Nov;34(11):2179-2186. Epub 2018 Aug 3 doi: 10.1007/s00381-018-3940-5. PMID: 30076436

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