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Membranous Nephropathy - Autoimmune Disorder Associated

MedGen UID:
888874
•Concept ID:
C4054542
•
Disease or Syndrome

Definition

Membranous nephropathy associated with an autoimmune disorder. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMembranous Nephropathy - Autoimmune Disorder Associated

Professional guidelines

PubMed

The management of membranous nephropathy-an update.
Caravaca-Fontán F, Fernández-Juárez GM, Floege J, Goumenos D, Kronbichler A, Turkmen K, van Kooten C, Frangou E, Stevens KI, Segelmark M, Tesar V, Anders HJ, Bruchfeld A
Nephrol Dial Transplant 2022 May 25;37(6):1033-1042. doi: 10.1093/ndt/gfab316. PMID: 34748001
Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.
Rovin BH, Adler SG, Barratt J, Bridoux F, Burdge KA, Chan TM, Cook HT, Fervenza FC, Gibson KL, Glassock RJ, Jayne DRW, Jha V, Liew A, Liu ZH, Mejía-Vilet JM, Nester CM, Radhakrishnan J, Rave EM, Reich HN, Ronco P, Sanders JF, Sethi S, Suzuki Y, Tang SCW, Tesar V, Vivarelli M, Wetzels JFM, Lytvyn L, Craig JC, Tunnicliffe DJ, Howell M, Tonelli MA, Cheung M, Earley A, Floege J
Kidney Int 2021 Oct;100(4):753-779. doi: 10.1016/j.kint.2021.05.015. PMID: 34556300
Primary Membranous Nephropathy.
Couser WG
Clin J Am Soc Nephrol 2017 Jun 7;12(6):983-997. Epub 2017 May 26 doi: 10.2215/CJN.11761116. PMID: 28550082Free PMC Article

Recent clinical studies

Etiology

The management of membranous nephropathy-an update.
Caravaca-Fontán F, Fernández-Juárez GM, Floege J, Goumenos D, Kronbichler A, Turkmen K, van Kooten C, Frangou E, Stevens KI, Segelmark M, Tesar V, Anders HJ, Bruchfeld A
Nephrol Dial Transplant 2022 May 25;37(6):1033-1042. doi: 10.1093/ndt/gfab316. PMID: 34748001
Membranous nephropathy.
Ronco P, Beck L, Debiec H, Fervenza FC, Hou FF, Jha V, Sethi S, Tong A, Vivarelli M, Wetzels J
Nat Rev Dis Primers 2021 Sep 30;7(1):69. doi: 10.1038/s41572-021-00303-z. PMID: 34593809
The anti-PLA2R antibody in membranous nephropathy: what we know and what remains a decade after its discovery.
van de Logt AE, Fresquet M, Wetzels JF, Brenchley P
Kidney Int 2019 Dec;96(6):1292-1302. Epub 2019 Aug 12 doi: 10.1016/j.kint.2019.07.014. PMID: 31611068
Exostosin 1/Exostosin 2-Associated Membranous Nephropathy.
Sethi S, Madden BJ, Debiec H, Charlesworth MC, Gross L, Ravindran A, Hummel AM, Specks U, Fervenza FC, Ronco P
J Am Soc Nephrol 2019 Jun;30(6):1123-1136. Epub 2019 May 6 doi: 10.1681/ASN.2018080852. PMID: 31061139Free PMC Article
Primary Membranous Nephropathy.
Couser WG
Clin J Am Soc Nephrol 2017 Jun 7;12(6):983-997. Epub 2017 May 26 doi: 10.2215/CJN.11761116. PMID: 28550082Free PMC Article

Diagnosis

Membranous nephropathy.
Ronco P, Beck L, Debiec H, Fervenza FC, Hou FF, Jha V, Sethi S, Tong A, Vivarelli M, Wetzels J
Nat Rev Dis Primers 2021 Sep 30;7(1):69. doi: 10.1038/s41572-021-00303-z. PMID: 34593809
Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.
Rovin BH, Adler SG, Barratt J, Bridoux F, Burdge KA, Chan TM, Cook HT, Fervenza FC, Gibson KL, Glassock RJ, Jayne DRW, Jha V, Liew A, Liu ZH, Mejía-Vilet JM, Nester CM, Radhakrishnan J, Rave EM, Reich HN, Ronco P, Sanders JF, Sethi S, Suzuki Y, Tang SCW, Tesar V, Vivarelli M, Wetzels JFM, Lytvyn L, Craig JC, Tunnicliffe DJ, Howell M, Tonelli MA, Cheung M, Earley A, Floege J
Kidney Int 2021 Oct;100(4):753-779. doi: 10.1016/j.kint.2021.05.015. PMID: 34556300
Mechanisms of Primary Membranous Nephropathy.
Gu Y, Xu H, Tang D
Biomolecules 2021 Mar 30;11(4) doi: 10.3390/biom11040513. PMID: 33808418Free PMC Article
New 'Antigens' in Membranous Nephropathy.
Sethi S
J Am Soc Nephrol 2021 Feb;32(2):268-278. Epub 2020 Dec 30 doi: 10.1681/ASN.2020071082. PMID: 33380523Free PMC Article
Primary Membranous Nephropathy.
Couser WG
Clin J Am Soc Nephrol 2017 Jun 7;12(6):983-997. Epub 2017 May 26 doi: 10.2215/CJN.11761116. PMID: 28550082Free PMC Article

Therapy

Anti-glomerular basement membrane vasculitis.
Ponticelli C, Calatroni M, Moroni G
Autoimmun Rev 2023 Jan;22(1):103212. Epub 2022 Oct 14 doi: 10.1016/j.autrev.2022.103212. PMID: 36252931
The management of membranous nephropathy-an update.
Caravaca-Fontán F, Fernández-Juárez GM, Floege J, Goumenos D, Kronbichler A, Turkmen K, van Kooten C, Frangou E, Stevens KI, Segelmark M, Tesar V, Anders HJ, Bruchfeld A
Nephrol Dial Transplant 2022 May 25;37(6):1033-1042. doi: 10.1093/ndt/gfab316. PMID: 34748001
Membranous nephropathy.
Ronco P, Beck L, Debiec H, Fervenza FC, Hou FF, Jha V, Sethi S, Tong A, Vivarelli M, Wetzels J
Nat Rev Dis Primers 2021 Sep 30;7(1):69. doi: 10.1038/s41572-021-00303-z. PMID: 34593809
Primary Membranous Nephropathy.
Couser WG
Clin J Am Soc Nephrol 2017 Jun 7;12(6):983-997. Epub 2017 May 26 doi: 10.2215/CJN.11761116. PMID: 28550082Free PMC Article
Anti-Glomerular Basement Membrane Disease.
McAdoo SP, Pusey CD
Clin J Am Soc Nephrol 2017 Jul 7;12(7):1162-1172. Epub 2017 May 17 doi: 10.2215/CJN.01380217. PMID: 28515156Free PMC Article

Prognosis

Membranous nephropathy: new pathogenic mechanisms and their clinical implications.
Hoxha E, Reinhard L, Stahl RAK
Nat Rev Nephrol 2022 Jul;18(7):466-478. Epub 2022 Apr 28 doi: 10.1038/s41581-022-00564-1. PMID: 35484394
Membranous nephropathy.
Ronco P, Beck L, Debiec H, Fervenza FC, Hou FF, Jha V, Sethi S, Tong A, Vivarelli M, Wetzels J
Nat Rev Dis Primers 2021 Sep 30;7(1):69. doi: 10.1038/s41572-021-00303-z. PMID: 34593809
Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.
Rovin BH, Adler SG, Barratt J, Bridoux F, Burdge KA, Chan TM, Cook HT, Fervenza FC, Gibson KL, Glassock RJ, Jayne DRW, Jha V, Liew A, Liu ZH, Mejía-Vilet JM, Nester CM, Radhakrishnan J, Rave EM, Reich HN, Ronco P, Sanders JF, Sethi S, Suzuki Y, Tang SCW, Tesar V, Vivarelli M, Wetzels JFM, Lytvyn L, Craig JC, Tunnicliffe DJ, Howell M, Tonelli MA, Cheung M, Earley A, Floege J
Kidney Int 2021 Oct;100(4):753-779. doi: 10.1016/j.kint.2021.05.015. PMID: 34556300
Anti-Glomerular Basement Membrane Disease.
McAdoo SP, Pusey CD
Clin J Am Soc Nephrol 2017 Jul 7;12(7):1162-1172. Epub 2017 May 17 doi: 10.2215/CJN.01380217. PMID: 28515156Free PMC Article
Primary glomerulonephritides.
Floege J, Amann K
Lancet 2016 May 14;387(10032):2036-48. Epub 2016 Feb 25 doi: 10.1016/S0140-6736(16)00272-5. PMID: 26921911

Clinical prediction guides

Expansion of Escherichia-Shigella in Gut Is Associated with the Onset and Response to Immunosuppressive Therapy of IgA Nephropathy.
Zhao J, Bai M, Ning X, Qin Y, Wang Y, Yu Z, Dong R, Zhang Y, Sun S
J Am Soc Nephrol 2022 Dec;33(12):2276-2292. Epub 2022 Aug 30 doi: 10.1681/ASN.2022020189. PMID: 36041791Free PMC Article
Membranous nephropathy.
Ronco P, Beck L, Debiec H, Fervenza FC, Hou FF, Jha V, Sethi S, Tong A, Vivarelli M, Wetzels J
Nat Rev Dis Primers 2021 Sep 30;7(1):69. doi: 10.1038/s41572-021-00303-z. PMID: 34593809
Glomerulonephritis Histopathological Pattern Change.
AlYousef A, AlSahow A, AlHelal B, Alqallaf A, Abdallah E, Abdellatif M, Nawar H, Elmahalawy R
BMC Nephrol 2020 May 18;21(1):186. doi: 10.1186/s12882-020-01836-3. PMID: 32423387Free PMC Article
Genetics of membranous nephropathy.
Gupta S, Köttgen A, Hoxha E, Brenchley P, Bockenhauer D, Stanescu HC, Kleta R
Nephrol Dial Transplant 2018 Sep 1;33(9):1493-1502. doi: 10.1093/ndt/gfx296. PMID: 29126273Free PMC Article
Anti-Glomerular Basement Membrane Disease.
McAdoo SP, Pusey CD
Clin J Am Soc Nephrol 2017 Jul 7;12(7):1162-1172. Epub 2017 May 17 doi: 10.2215/CJN.01380217. PMID: 28515156Free PMC Article

Recent systematic reviews

Systematic Review of Safety and Efficacy of Second- and Third-Generation CD20-Targeting Biologics in Treating Immune-Mediated Disorders.
Kaegi C, Wuest B, Crowley C, Boyman O
Front Immunol 2021;12:788830. Epub 2022 Feb 2 doi: 10.3389/fimmu.2021.788830. PMID: 35185862Free PMC Article
Immunosuppressive treatment for primary membranous nephropathy in adults with nephrotic syndrome.
von Groote TC, Williams G, Au EH, Chen Y, Mathew AT, Hodson EM, Tunnicliffe DJ
Cochrane Database Syst Rev 2021 Nov 15;11(11):CD004293. doi: 10.1002/14651858.CD004293.pub4. PMID: 34778952Free PMC Article
Systematic Review of Safety and Efficacy of Rituximab in Treating Immune-Mediated Disorders.
Kaegi C, Wuest B, Schreiner J, Steiner UC, Vultaggio A, Matucci A, Crowley C, Boyman O
Front Immunol 2019;10:1990. Epub 2019 Sep 6 doi: 10.3389/fimmu.2019.01990. PMID: 31555262Free PMC Article
Induction therapy for membranous lupus nephritis: a systematic review and network meta-analysis.
Tang KT, Tseng CH, Hsieh TY, Chen DY
Int J Rheum Dis 2018 Jun;21(6):1163-1172. doi: 10.1111/1756-185X.13321. PMID: 29879319
Prevalence of cancer in membranous nephropathy: a systematic review and meta-analysis of observational studies.
Leeaphorn N, Kue-A-Pai P, Thamcharoen N, Ungprasert P, Stokes MB, Knight EL
Am J Nephrol 2014;40(1):29-35. Epub 2014 Jun 28 doi: 10.1159/000364782. PMID: 24993974

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