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Congenital Nephrotic Syndrome - Infection Associated

MedGen UID:
889751
•Concept ID:
C4055192
•
Disease or Syndrome

Definition

Nephrotic syndrome presenting within the first three months of life, and which is associated with an infectious process. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCongenital Nephrotic Syndrome - Infection Associated

Professional guidelines

PubMed

Prolonged Impairment of Immunological Memory After Anti-CD20 Treatment in Pediatric Idiopathic Nephrotic Syndrome.
Colucci M, Carsetti R, Serafinelli J, Rocca S, Massella L, Gargiulo A, Lo Russo A, Capponi C, Cotugno N, Porzio O, Onetti Muda A, Palma P, Emma F, Vivarelli M
Front Immunol 2019;10:1653. Epub 2019 Jul 16 doi: 10.3389/fimmu.2019.01653. PMID: 31379849Free PMC Article

Recent clinical studies

Etiology

Rituximab-associated hypogammaglobulinemia in children with idiopathic nephrotic syndrome: results of an ESPN survey.
Zurowska A, Drozynska-Duklas M, Topaloglu R, Bouts A, Boyer O, Shenoy M, Vivarelli M; ESPN Glomerulonephritis Working Group
Pediatr Nephrol 2023 Sep;38(9):3035-3042. Epub 2023 Apr 4 doi: 10.1007/s00467-023-05913-1. PMID: 37014530Free PMC Article
Changes in Patterns of Infection Associated with Pediatric Idiopathic Nephrotic Syndrome: A Single-Center Experience in Japan.
Takao H, Nishi K, Funaki T, Inoki Y, Osaka K, Nada T, Yokota S, Sato M, Ogura M, Ishikura K, Ishiguro A, Kamei K
J Pediatr 2023 Mar;254:11-16.e1. Epub 2022 Oct 9 doi: 10.1016/j.jpeds.2022.10.005. PMID: 36223870
Long-Term Efficacy and Safety of Repeated Rituximab to Maintain Remission in Idiopathic Childhood Nephrotic Syndrome: An International Study.
Chan EY, Yu ELM, Angeletti A, Arslan Z, Basu B, Boyer O, Chan CY, Colucci M, Dorval G, Dossier C, Drovandi S, Ghiggeri GM, Gipson DS, Hamada R, Hogan J, Ishikura K, Kamei K, Kemper MJ, Ma AL, Parekh RS, Radhakrishnan S, Saini P, Shen Q, Sinha R, Subun C, Teo S, Vivarelli M, Webb H, Xu H, Yap HK, Tullus K
J Am Soc Nephrol 2022 Jun;33(6):1193-1207. Epub 2022 Mar 30 doi: 10.1681/ASN.2021111472. PMID: 35354600Free PMC Article
Acute Kidney Injury and CKD Associated with Hematopoietic Stem Cell Transplantation.
Renaghan AD, Jaimes EA, Malyszko J, Perazella MA, Sprangers B, Rosner MH
Clin J Am Soc Nephrol 2020 Feb 7;15(2):289-297. Epub 2019 Dec 13 doi: 10.2215/CJN.08580719. PMID: 31836598Free PMC Article
Rituximab-associated agranulocytosis in children with refractory idiopathic nephrotic syndrome: case series and review of literature.
Kamei K, Takahashi M, Fuyama M, Saida K, Machida H, Sato M, Ogura M, Ito S
Nephrol Dial Transplant 2015 Jan;30(1):91-6. Epub 2014 Aug 1 doi: 10.1093/ndt/gfu258. PMID: 25085238

Diagnosis

Rituximab-associated hypogammaglobulinemia in children with idiopathic nephrotic syndrome: results of an ESPN survey.
Zurowska A, Drozynska-Duklas M, Topaloglu R, Bouts A, Boyer O, Shenoy M, Vivarelli M; ESPN Glomerulonephritis Working Group
Pediatr Nephrol 2023 Sep;38(9):3035-3042. Epub 2023 Apr 4 doi: 10.1007/s00467-023-05913-1. PMID: 37014530Free PMC Article
The Immune System and Idiopathic Nephrotic Syndrome.
Campbell RE, Thurman JM
Clin J Am Soc Nephrol 2022 Dec;17(12):1823-1834. Epub 2022 Oct 5 doi: 10.2215/CJN.07180622. PMID: 36198505Free PMC Article
An updated view of the pathogenesis of steroid-sensitive nephrotic syndrome.
Horinouchi T, Nozu K, Iijima K
Pediatr Nephrol 2022 Sep;37(9):1957-1965. Epub 2022 Jan 10 doi: 10.1007/s00467-021-05401-4. PMID: 35006356Free PMC Article
Acute Kidney Injury and CKD Associated with Hematopoietic Stem Cell Transplantation.
Renaghan AD, Jaimes EA, Malyszko J, Perazella MA, Sprangers B, Rosner MH
Clin J Am Soc Nephrol 2020 Feb 7;15(2):289-297. Epub 2019 Dec 13 doi: 10.2215/CJN.08580719. PMID: 31836598Free PMC Article
The etiology of congenital nephrotic syndrome: current status and challenges.
Wang JJ, Mao JH
World J Pediatr 2016 May;12(2):149-58. Epub 2016 Mar 9 doi: 10.1007/s12519-016-0009-y. PMID: 26961288

Therapy

Rituximab-associated hypogammaglobulinemia in children with idiopathic nephrotic syndrome: results of an ESPN survey.
Zurowska A, Drozynska-Duklas M, Topaloglu R, Bouts A, Boyer O, Shenoy M, Vivarelli M; ESPN Glomerulonephritis Working Group
Pediatr Nephrol 2023 Sep;38(9):3035-3042. Epub 2023 Apr 4 doi: 10.1007/s00467-023-05913-1. PMID: 37014530Free PMC Article
Changes in Patterns of Infection Associated with Pediatric Idiopathic Nephrotic Syndrome: A Single-Center Experience in Japan.
Takao H, Nishi K, Funaki T, Inoki Y, Osaka K, Nada T, Yokota S, Sato M, Ogura M, Ishikura K, Ishiguro A, Kamei K
J Pediatr 2023 Mar;254:11-16.e1. Epub 2022 Oct 9 doi: 10.1016/j.jpeds.2022.10.005. PMID: 36223870
Long-Term Efficacy and Safety of Repeated Rituximab to Maintain Remission in Idiopathic Childhood Nephrotic Syndrome: An International Study.
Chan EY, Yu ELM, Angeletti A, Arslan Z, Basu B, Boyer O, Chan CY, Colucci M, Dorval G, Dossier C, Drovandi S, Ghiggeri GM, Gipson DS, Hamada R, Hogan J, Ishikura K, Kamei K, Kemper MJ, Ma AL, Parekh RS, Radhakrishnan S, Saini P, Shen Q, Sinha R, Subun C, Teo S, Vivarelli M, Webb H, Xu H, Yap HK, Tullus K
J Am Soc Nephrol 2022 Jun;33(6):1193-1207. Epub 2022 Mar 30 doi: 10.1681/ASN.2021111472. PMID: 35354600Free PMC Article
Acute Kidney Injury and CKD Associated with Hematopoietic Stem Cell Transplantation.
Renaghan AD, Jaimes EA, Malyszko J, Perazella MA, Sprangers B, Rosner MH
Clin J Am Soc Nephrol 2020 Feb 7;15(2):289-297. Epub 2019 Dec 13 doi: 10.2215/CJN.08580719. PMID: 31836598Free PMC Article
Rituximab-associated agranulocytosis in children with refractory idiopathic nephrotic syndrome: case series and review of literature.
Kamei K, Takahashi M, Fuyama M, Saida K, Machida H, Sato M, Ogura M, Ito S
Nephrol Dial Transplant 2015 Jan;30(1):91-6. Epub 2014 Aug 1 doi: 10.1093/ndt/gfu258. PMID: 25085238

Prognosis

Incidence of idiopathic nephrotic syndrome during the Covid-19 pandemic in the Paris area (France) and in the Netherlands.
Veltkamp F, Thenot V, Mussies C, van Lieshout B, Peters-Sengers H, Kers J, Khan DH, Hogan J, Florquin S, Bouts AHM, Dossier C; NEPHROVIR network, the LEARNS consortium
Pediatr Nephrol 2023 Nov;38(11):3681-3692. Epub 2023 May 16 doi: 10.1007/s00467-023-06006-9. PMID: 37191940Free PMC Article
Rituximab-associated hypogammaglobulinemia in children with idiopathic nephrotic syndrome: results of an ESPN survey.
Zurowska A, Drozynska-Duklas M, Topaloglu R, Bouts A, Boyer O, Shenoy M, Vivarelli M; ESPN Glomerulonephritis Working Group
Pediatr Nephrol 2023 Sep;38(9):3035-3042. Epub 2023 Apr 4 doi: 10.1007/s00467-023-05913-1. PMID: 37014530Free PMC Article
Long-Term Efficacy and Safety of Repeated Rituximab to Maintain Remission in Idiopathic Childhood Nephrotic Syndrome: An International Study.
Chan EY, Yu ELM, Angeletti A, Arslan Z, Basu B, Boyer O, Chan CY, Colucci M, Dorval G, Dossier C, Drovandi S, Ghiggeri GM, Gipson DS, Hamada R, Hogan J, Ishikura K, Kamei K, Kemper MJ, Ma AL, Parekh RS, Radhakrishnan S, Saini P, Shen Q, Sinha R, Subun C, Teo S, Vivarelli M, Webb H, Xu H, Yap HK, Tullus K
J Am Soc Nephrol 2022 Jun;33(6):1193-1207. Epub 2022 Mar 30 doi: 10.1681/ASN.2021111472. PMID: 35354600Free PMC Article
Acute Kidney Injury and CKD Associated with Hematopoietic Stem Cell Transplantation.
Renaghan AD, Jaimes EA, Malyszko J, Perazella MA, Sprangers B, Rosner MH
Clin J Am Soc Nephrol 2020 Feb 7;15(2):289-297. Epub 2019 Dec 13 doi: 10.2215/CJN.08580719. PMID: 31836598Free PMC Article
Long-term outcome of congenital nephrotic syndrome after kidney transplantation in Japan.
Hamasaki Y, Muramatsu M, Hamada R, Ishikura K, Hataya H, Satou H, Honda M, Nakanishi K, Shishido S
Clin Exp Nephrol 2018 Jun;22(3):719-726. Epub 2017 Nov 28 doi: 10.1007/s10157-017-1508-4. PMID: 29185126

Clinical prediction guides

Rituximab-associated hypogammaglobulinemia in children with idiopathic nephrotic syndrome: results of an ESPN survey.
Zurowska A, Drozynska-Duklas M, Topaloglu R, Bouts A, Boyer O, Shenoy M, Vivarelli M; ESPN Glomerulonephritis Working Group
Pediatr Nephrol 2023 Sep;38(9):3035-3042. Epub 2023 Apr 4 doi: 10.1007/s00467-023-05913-1. PMID: 37014530Free PMC Article
Changes in Patterns of Infection Associated with Pediatric Idiopathic Nephrotic Syndrome: A Single-Center Experience in Japan.
Takao H, Nishi K, Funaki T, Inoki Y, Osaka K, Nada T, Yokota S, Sato M, Ogura M, Ishikura K, Ishiguro A, Kamei K
J Pediatr 2023 Mar;254:11-16.e1. Epub 2022 Oct 9 doi: 10.1016/j.jpeds.2022.10.005. PMID: 36223870
The Immune System and Idiopathic Nephrotic Syndrome.
Campbell RE, Thurman JM
Clin J Am Soc Nephrol 2022 Dec;17(12):1823-1834. Epub 2022 Oct 5 doi: 10.2215/CJN.07180622. PMID: 36198505Free PMC Article
Long-term outcome of congenital nephrotic syndrome after kidney transplantation in Japan.
Hamasaki Y, Muramatsu M, Hamada R, Ishikura K, Hataya H, Satou H, Honda M, Nakanishi K, Shishido S
Clin Exp Nephrol 2018 Jun;22(3):719-726. Epub 2017 Nov 28 doi: 10.1007/s10157-017-1508-4. PMID: 29185126
Rituximab-associated agranulocytosis in children with refractory idiopathic nephrotic syndrome: case series and review of literature.
Kamei K, Takahashi M, Fuyama M, Saida K, Machida H, Sato M, Ogura M, Ito S
Nephrol Dial Transplant 2015 Jan;30(1):91-6. Epub 2014 Aug 1 doi: 10.1093/ndt/gfu258. PMID: 25085238

Recent systematic reviews

Immune tolerance induction for treating inhibitors in people with congenital haemophilia A or B.
Athale AH, Marcucci M, Iorio A
Cochrane Database Syst Rev 2014 Apr 24;2014(4):CD010561. doi: 10.1002/14651858.CD010561.pub2. PMID: 24763974Free PMC Article

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