U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Keratinocyte vacuolization

MedGen UID:
905510
•Concept ID:
C4230513
•
Finding
Synonym: Vacuolization of keratinocytes
 
HPO: HP:0034703

Definition

Increased number of vacuoles (membrane-bound organelles that areempty of cytoplasm, lined with a membrane, and filled with fluid) in keratinocytes. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVKeratinocyte vacuolization

Professional guidelines

PubMed

Ichthyosis with confetti: clinics, molecular genetics and management.
Guerra L, Diociaiuti A, El Hachem M, Castiglia D, Zambruno G
Orphanet J Rare Dis 2015 Sep 17;10:115. doi: 10.1186/s13023-015-0336-4. PMID: 26381864Free PMC Article

Recent clinical studies

Etiology

Overlap between maculopapular exanthema and drug reaction with eosinophilia and systemic symptoms among cutaneous adverse drug reactions in a dermatology ward.
Pinto Gouveia M, Gameiro A, Coutinho I, Pereira N, Cardoso JC, Gonçalo M
Br J Dermatol 2016 Dec;175(6):1274-1283. Epub 2016 Sep 6 doi: 10.1111/bjd.14704. PMID: 27128886
Immunohistochemical expression of aberrant Notch-1 signaling in vitiligo: an implication for pathogenesis.
Seleit I, Bakry OA, Abdou AG, Dawoud NM
Ann Diagn Pathol 2014 Jun;18(3):117-24. Epub 2014 Jan 13 doi: 10.1016/j.anndiagpath.2014.01.002. PMID: 24560443

Diagnosis

Overlap between maculopapular exanthema and drug reaction with eosinophilia and systemic symptoms among cutaneous adverse drug reactions in a dermatology ward.
Pinto Gouveia M, Gameiro A, Coutinho I, Pereira N, Cardoso JC, Gonçalo M
Br J Dermatol 2016 Dec;175(6):1274-1283. Epub 2016 Sep 6 doi: 10.1111/bjd.14704. PMID: 27128886
Ichthyosis with confetti: clinics, molecular genetics and management.
Guerra L, Diociaiuti A, El Hachem M, Castiglia D, Zambruno G
Orphanet J Rare Dis 2015 Sep 17;10:115. doi: 10.1186/s13023-015-0336-4. PMID: 26381864Free PMC Article

Prognosis

Immunolocalization of tenascin-C in vitiligo.
Abdou AG, Maraee AH, Shoeib MA, Elbana R
Appl Immunohistochem Mol Morphol 2012 Oct;20(5):501-11. doi: 10.1097/PAI.0b013e318246c793. PMID: 22495383

Clinical prediction guides

Immunolocalization of tenascin-C in vitiligo.
Abdou AG, Maraee AH, Shoeib MA, Elbana R
Appl Immunohistochem Mol Morphol 2012 Oct;20(5):501-11. doi: 10.1097/PAI.0b013e318246c793. PMID: 22495383

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...