From HPO
Polyarticular arthritis- MedGen UID:
- 56408
- •Concept ID:
- C0162323
- •
- Disease or Syndrome
An arthritis affecting five or more separate joints.
Pulmonary infiltrates- MedGen UID:
- 116009
- •Concept ID:
- C0235896
- •
- Finding
A finding indicating the presence of an inflammatory or neoplastic cellular infiltrate in the lung parenchyma.
Histiocytosis- MedGen UID:
- 6845
- •Concept ID:
- C0019618
- •
- Neoplastic Process
An excessive number of histiocytes (tissue macrophages).
Recurrent infections- MedGen UID:
- 65998
- •Concept ID:
- C0239998
- •
- Finding
Increased susceptibility to infections.
Increased circulating antibody level- MedGen UID:
- 1713383
- •Concept ID:
- C5397581
- •
- Finding
An increased level of gamma globulin (immunoglobulin) in the blood.
Increased alpha-globulin- MedGen UID:
- 257902
- •Concept ID:
- C1167806
- •
- Finding
An abnormally increased level of circulating alpha-globulin. Alpha globulins are a group of serum proteins defined by their mobility on serum electrophoresis. The alpha1-protein fraction is comprised of alpha1-antitrypsin, thyroid-binding globulin, and transcortin. Ceruloplasmin, alpha2-macroglobulin, and haptoglobin contribute to the alpha2-protein band. The alpha2 component is increased as an acute-phase reactant.
- Abnormality of metabolism/homeostasis
- Abnormality of the immune system
- Abnormality of the musculoskeletal system
- Abnormality of the respiratory system