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Cutaneous adenocystic carcinoma

MedGen UID:
91071
•Concept ID:
C0346017
•
Neoplastic Process
Synonyms: adenoid cystic carcinoma of skin; adenoid cystic carcinoma of the skin; adenoid cystic cutaneous carcinoma; Adenoid cystic eccrine carcinoma; adenoid cystic eccrine carcinoma; adenoid cystic eccrine carcinoma (morphologic abnormality); adenoid cystic eccrine carcinoma of skin; adenoid cystic skin carcinoma; cutaneous adenocystic carcinoma; primary cutaneous adenocystic carcinoma; skin of body adenoid cystic carcinoma
SNOMED CT: Adenoid cystic eccrine carcinoma (399968001)
 
Monarch Initiative: MONDO:0003180

Definition

A adenoid cystic carcinoma that involves the skin of body. [from MONDO]

Professional guidelines

PubMed

Cutaneous Sweat Gland Carcinomas with Basaloid Differentiation: An Update with Emphasis on Differential Diagnoses.
Flux K, Brenn T
Clin Lab Med 2017 Sep;37(3):587-601. Epub 2017 Jun 9 doi: 10.1016/j.cll.2017.05.006. PMID: 28802502
Antibodies to intermediate filament proteins. The differential diagnosis of cutaneous tumors.
Miettinen M, Lehto VP, Virtanen I
Arch Dermatol 1985 Jun;121(6):736-41. PMID: 2408582

Recent clinical studies

Etiology

Primary cutaneous adenoid cystic carcinoma: a clinicopathologic, immunohistochemical, and fluorescence in-situ hybridisation study of 13 cases.
Lv JJ, Ren M, Cai X, Hu J, Kong JC, Kong YY
Histopathology 2022 Jan;80(2):407-419. Epub 2021 Nov 11 doi: 10.1111/his.14565. PMID: 34519081
Primary adenocarcinomas of the vulva and related structures: An enigmatic and diverse group of tumors(✰).
Desouki MM, Fadare O
Semin Diagn Pathol 2021 Jan;38(1):71-84. Epub 2020 Sep 25 doi: 10.1053/j.semdp.2020.09.011. PMID: 33032903
MYB, CD117 and SOX-10 expression in cutaneous adnexal tumors.
Evangelista MT, North JP
J Cutan Pathol 2017 May;44(5):444-450. Epub 2017 Feb 14 doi: 10.1111/cup.12904. PMID: 28098399
GATA3 Expression in Normal Skin and in Benign and Malignant Epidermal and Cutaneous Adnexal Neoplasms.
Mertens RB, de Peralta-Venturina MN, Balzer BL, Frishberg DP
Am J Dermatopathol 2015 Dec;37(12):885-91. doi: 10.1097/DAD.0000000000000306. PMID: 26595821Free PMC Article
Molecular pathology of skin neoplasms of the head and neck.
Kraft S, Granter SR
Arch Pathol Lab Med 2014 Jun;138(6):759-87. doi: 10.5858/arpa.2013-0157-RA. PMID: 24878016

Diagnosis

Malignant Sweat Gland Tumors.
Ahn CS, Sangüeza OP
Hematol Oncol Clin North Am 2019 Feb;33(1):53-71. doi: 10.1016/j.hoc.2018.09.002. PMID: 30497677
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149
Primary cutaneous cribriform apocrine carcinoma: Case report and literature review.
Wu JD, Changchien CH, Liao KS
Indian J Dermatol Venereol Leprol 2018 Sep-Oct;84(5):569-572. doi: 10.4103/ijdvl.IJDVL_830_16. PMID: 29735815
Cylindroma: an update.
Jordão C, de Magalhães TC, Cuzzi T, Ramos-e-Silva M
Int J Dermatol 2015 Mar;54(3):275-8. Epub 2014 Dec 16 doi: 10.1111/ijd.12600. PMID: 25515269
Perineural tumor spread.
Maroldi R, Farina D, Borghesi A, Marconi A, Gatti E
Neuroimaging Clin N Am 2008 May;18(2):413-29, xi. doi: 10.1016/j.nic.2008.01.001. PMID: 18466839

Therapy

Effectiveness and tolerance of electrochemotherapy as palliative therapy for patients with head and neck cancer and malignant melanoma and its relation to early skin reaction.
Caballero-Borrego M, Coll S, Navarrete P
Braz J Otorhinolaryngol 2024 Jan-Feb;90(1):101365. Epub 2023 Nov 22 doi: 10.1016/j.bjorl.2023.101365. PMID: 38006727Free PMC Article
Change of Circulating and Tissue-Based miR-20a in Human Cancers and Associated Prognostic Implication: A Systematic Review and Meta-Analysis.
Zhang Q, Wang Q, Sun W, Gao F, Liu L, Cheng L, Li Z
Biomed Res Int 2018;2018:6124927. Epub 2018 Nov 25 doi: 10.1155/2018/6124927. PMID: 30596096Free PMC Article
Reirradiation of Recurrent and Second Primary Head and Neck Cancer With Proton Therapy.
McDonald MW, Zolali-Meybodi O, Lehnert SJ, Estabrook NC, Liu Y, Cohen-Gadol AA, Moore MG
Int J Radiat Oncol Biol Phys 2016 Nov 15;96(4):808-819. Epub 2016 Aug 3 doi: 10.1016/j.ijrobp.2016.07.037. PMID: 27788954
Molecular pathology of skin neoplasms of the head and neck.
Kraft S, Granter SR
Arch Pathol Lab Med 2014 Jun;138(6):759-87. doi: 10.5858/arpa.2013-0157-RA. PMID: 24878016
Cisplatin combination chemotherapy in squamous cell carcinoma and adenoid cystic carcinoma of the skin.
Ikegawa S, Saida T, Obayashi H, Sasaki A, Esumi H, Ikeda S, Kiyohara Y, Hayasaka K, Ishihara K
J Dermatol 1989 Jun;16(3):227-30. doi: 10.1111/j.1346-8138.1989.tb01254.x. PMID: 2551943

Prognosis

PRIMARY CUTANEOUS ADENOID CYSTIC CARCINOMA IN THE TRUNK: CASE REPORT AND LITERATURE REVIEW.
Moreno M, de O, Czarnobai I, Cássia B
Exp Oncol 2022 Aug;44(2):174-176. doi: 10.32471/exp-oncology.2312-8852.vol-44-no-2.18006. PMID: 35964642
Primary cutaneous adenoid cystic carcinoma: a clinicopathologic, immunohistochemical, and fluorescence in-situ hybridisation study of 13 cases.
Lv JJ, Ren M, Cai X, Hu J, Kong JC, Kong YY
Histopathology 2022 Jan;80(2):407-419. Epub 2021 Nov 11 doi: 10.1111/his.14565. PMID: 34519081
Analysis of Characteristics and Survival of Primary Cutaneous Adenoid Cystic Carcinoma of the Head and Neck.
Behbahani S, Wassef DW, Povolotskiy R, Pinto J, Joseph N, Paskhover B
Ann Otol Rhinol Laryngol 2021 Jan;130(1):12-17. Epub 2020 Jun 21 doi: 10.1177/0003489420936719. PMID: 32567392
Adenoid cystic carcinoma of the palate with isolated cutaneous metastasis: a unique case and review of current and future treatment modalities of metastatic disease.
Armstrong LTD, Subramaniam SS, Borgna S
Int J Oral Maxillofac Surg 2020 Jun;49(6):700-708. Epub 2019 Dec 28 doi: 10.1016/j.ijom.2019.11.012. PMID: 31892444
Perineural tumor spread.
Maroldi R, Farina D, Borghesi A, Marconi A, Gatti E
Neuroimaging Clin N Am 2008 May;18(2):413-29, xi. doi: 10.1016/j.nic.2008.01.001. PMID: 18466839

Clinical prediction guides

Basal cell carcinoma: Histopathological gamut.
Sharma P, Wadhwan V, Bansal V
Indian J Dent Res 2021 Jul-Sep;32(3):407-410. doi: 10.4103/ijdr.IJDR_227_19. PMID: 35229784
Analysis of Characteristics and Survival of Primary Cutaneous Adenoid Cystic Carcinoma of the Head and Neck.
Behbahani S, Wassef DW, Povolotskiy R, Pinto J, Joseph N, Paskhover B
Ann Otol Rhinol Laryngol 2021 Jan;130(1):12-17. Epub 2020 Jun 21 doi: 10.1177/0003489420936719. PMID: 32567392
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149
Primary cutaneous adenoid cystic carcinoma of the eyelid and literature review.
Coban DT, Erol MK, Suren D, Tutus B
Arq Bras Oftalmol 2015 Sep-Oct;78(5):323-5. doi: 10.5935/0004-2749.20150085. PMID: 26466235
Detection of MYB Alterations and Other Immunohistochemical Markers in Primary Cutaneous Adenoid Cystic Carcinoma.
North JP, McCalmont TH, Fehr A, van Zante A, Stenman G, LeBoit PE
Am J Surg Pathol 2015 Oct;39(10):1347-56. doi: 10.1097/PAS.0000000000000463. PMID: 26076064

Recent systematic reviews

Change of Circulating and Tissue-Based miR-20a in Human Cancers and Associated Prognostic Implication: A Systematic Review and Meta-Analysis.
Zhang Q, Wang Q, Sun W, Gao F, Liu L, Cheng L, Li Z
Biomed Res Int 2018;2018:6124927. Epub 2018 Nov 25 doi: 10.1155/2018/6124927. PMID: 30596096Free PMC Article
Cylindroma of head and neck: review of the literature and report of two rare cases.
Singh DD, Naujoks C, Depprich R, Schulte KW, Jankowiak F, Kübler NR, Handschel J
J Craniomaxillofac Surg 2013 Sep;41(6):516-21. Epub 2012 Dec 21 doi: 10.1016/j.jcms.2012.11.016. PMID: 23260808

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