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Tonsillopharyngitis

MedGen UID:
922968
•Concept ID:
C0749591
•
Disease or Syndrome

Definition

Inflammation of the palatine tonsils and the posterior pharynx (throat). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTonsillopharyngitis

Professional guidelines

PubMed

Complementary and alternative medicine in the (symptomatic) treatment of acute tonsillitis in children: A systematic review.
Büttner R, Schwermer M, Ostermann T, Längler A, Zuzak T
Complement Ther Med 2023 May;73:102940. Epub 2023 Mar 1 doi: 10.1016/j.ctim.2023.102940. PMID: 36868289
Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics.
Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST, Taubert KA
Circulation 2009 Mar 24;119(11):1541-51. Epub 2009 Feb 26 doi: 10.1161/CIRCULATIONAHA.109.191959. PMID: 19246689

Recent clinical studies

Etiology

Antimicrobial treatment of ENT infections.
Cohen R, Madhi F, Thollot F, Hau I, Vie le Sage F, Lemaître C, Magendie C, Werner A, Gelbert N, Cohen JF, Couloigner V
Infect Dis Now 2023 Nov;53(8S):104785. Epub 2023 Sep 18 doi: 10.1016/j.idnow.2023.104785. PMID: 37730165
Different antibiotic treatments for group A streptococcal pharyngitis.
van Driel ML, De Sutter AI, Thorning S, Christiaens T
Cochrane Database Syst Rev 2021 Mar 17;3(3):CD004406. doi: 10.1002/14651858.CD004406.pub5. PMID: 33728634Free PMC Article
Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics.
Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST, Taubert KA
Circulation 2009 Mar 24;119(11):1541-51. Epub 2009 Feb 26 doi: 10.1161/CIRCULATIONAHA.109.191959. PMID: 19246689
Identifying poststreptococcal glomerulonephritis.
Lang MM, Towers C
Nurse Pract 2001 Aug;26(8):34, 37-42, 44-7; quiz 48-9. doi: 10.1097/00006205-200108000-00004. PMID: 11521409

Diagnosis

Antimicrobial treatment of ENT infections.
Cohen R, Madhi F, Thollot F, Hau I, Vie le Sage F, Lemaître C, Magendie C, Werner A, Gelbert N, Cohen JF, Couloigner V
Infect Dis Now 2023 Nov;53(8S):104785. Epub 2023 Sep 18 doi: 10.1016/j.idnow.2023.104785. PMID: 37730165
Different antibiotic treatments for group A streptococcal pharyngitis.
van Driel ML, De Sutter AI, Thorning S, Christiaens T
Cochrane Database Syst Rev 2021 Mar 17;3(3):CD004406. doi: 10.1002/14651858.CD004406.pub5. PMID: 33728634Free PMC Article
Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
Lemierre's syndrome: A forgotten and re-emerging infection.
Lee WS, Jean SS, Chen FL, Hsieh SM, Hsueh PR
J Microbiol Immunol Infect 2020 Aug;53(4):513-517. Epub 2020 Apr 4 doi: 10.1016/j.jmii.2020.03.027. PMID: 32303484
Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics.
Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST, Taubert KA
Circulation 2009 Mar 24;119(11):1541-51. Epub 2009 Feb 26 doi: 10.1161/CIRCULATIONAHA.109.191959. PMID: 19246689

Therapy

Antimicrobial treatment of ENT infections.
Cohen R, Madhi F, Thollot F, Hau I, Vie le Sage F, Lemaître C, Magendie C, Werner A, Gelbert N, Cohen JF, Couloigner V
Infect Dis Now 2023 Nov;53(8S):104785. Epub 2023 Sep 18 doi: 10.1016/j.idnow.2023.104785. PMID: 37730165
Different antibiotic treatments for group A streptococcal pharyngitis.
van Driel ML, De Sutter AI, Thorning S, Christiaens T
Cochrane Database Syst Rev 2021 Mar 17;3(3):CD004406. doi: 10.1002/14651858.CD004406.pub5. PMID: 33728634Free PMC Article
Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
Lemierre's syndrome: A forgotten and re-emerging infection.
Lee WS, Jean SS, Chen FL, Hsieh SM, Hsueh PR
J Microbiol Immunol Infect 2020 Aug;53(4):513-517. Epub 2020 Apr 4 doi: 10.1016/j.jmii.2020.03.027. PMID: 32303484
Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics.
Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST, Taubert KA
Circulation 2009 Mar 24;119(11):1541-51. Epub 2009 Feb 26 doi: 10.1161/CIRCULATIONAHA.109.191959. PMID: 19246689

Prognosis

To prescribe or not to prescribe for paediatric sore throat: a retrospective cohort study comparing clinician-led antibiotic prescriptions to FeverPAIN and Centor scoring in a tertiary paediatric emergency department and a national review of practice.
Malley M, Driver K, Costelloe M, Monaghan I, Jefferson L, Poole L, Lewis C, Salt R, Marlow R
Emerg Med J 2021 Aug;38(8):613-616. Epub 2021 Apr 15 doi: 10.1136/emermed-2020-210786. PMID: 33858860
Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
EPs 7630 is effective and safe in children under 6 years with acute respiratory tract infections: clinical studies revisited.
Kamin W, Funk P, Seifert G, Zimmermann A, Lehmacher W
Curr Med Res Opin 2018 Mar;34(3):475-485. Epub 2017 Dec 8 doi: 10.1080/03007995.2017.1402754. PMID: 29119837
Cefditoren in upper and lower community-acquired respiratory tract infections.
Soriano F, Giménez MJ, Aguilar L
Drug Des Devel Ther 2011 Feb 9;5:85-94. doi: 10.2147/DDDT.S9499. PMID: 21340042Free PMC Article
Tonsillopharyngitis 1994.
Denny FW Jr
Pediatr Rev 1994 May;15(5):185-91. doi: 10.1542/pir.15-5-185. PMID: 8036194

Clinical prediction guides

Role of multidimensional factors in the diagnosis and treatment of tonsillopharyngitis in primary care: a qualitative study.
Rutkovska I, Linde-Ozola Z, Poplavska E
BMC Prim Care 2022 Nov 4;23(1):275. doi: 10.1186/s12875-022-01881-x. PMID: 36333657Free PMC Article
To prescribe or not to prescribe for paediatric sore throat: a retrospective cohort study comparing clinician-led antibiotic prescriptions to FeverPAIN and Centor scoring in a tertiary paediatric emergency department and a national review of practice.
Malley M, Driver K, Costelloe M, Monaghan I, Jefferson L, Poole L, Lewis C, Salt R, Marlow R
Emerg Med J 2021 Aug;38(8):613-616. Epub 2021 Apr 15 doi: 10.1136/emermed-2020-210786. PMID: 33858860
Factors Affecting Cervical Lymph Node Suppuration in Oropharyngeal Tularemia Cases.
Ince N, Gozdas HT
J Coll Physicians Surg Pak 2021 Feb;31(2):193-196. doi: 10.29271/jcpsp.2021.02.193. PMID: 33645188
Clinical Practice Guideline: Sore Throat.
Krüger K, Töpfner N, Berner R, Windfuhr J, Oltrogge JH; Guideline group
Dtsch Arztebl Int 2021 Mar 19;118(11):188-94. doi: 10.3238/arztebl.m2021.0121. PMID: 33602392Free PMC Article
Cefditoren in upper and lower community-acquired respiratory tract infections.
Soriano F, Giménez MJ, Aguilar L
Drug Des Devel Ther 2011 Feb 9;5:85-94. doi: 10.2147/DDDT.S9499. PMID: 21340042Free PMC Article

Recent systematic reviews

Different antibiotic treatments for group A streptococcal pharyngitis.
Hedin K, Thorning S, van Driel ML
Cochrane Database Syst Rev 2023 Nov 15;11(11):CD004406. doi: 10.1002/14651858.CD004406.pub6. PMID: 37965935Free PMC Article
Complementary and alternative medicine in the (symptomatic) treatment of acute tonsillitis in children: A systematic review.
Büttner R, Schwermer M, Ostermann T, Längler A, Zuzak T
Complement Ther Med 2023 May;73:102940. Epub 2023 Mar 1 doi: 10.1016/j.ctim.2023.102940. PMID: 36868289
Flavonoids for Treating Viral Acute Respiratory Tract Infections: A Systematic Review and Meta-Analysis of 30 Randomized Controlled Trials.
Yao J, Zhang Y, Wang XZ, Zhao J, Yang ZJ, Lin YP, Sun L, Lu QY, Fan GJ
Front Public Health 2022;10:814669. Epub 2022 Feb 16 doi: 10.3389/fpubh.2022.814669. PMID: 35252093Free PMC Article
Different antibiotic treatments for group A streptococcal pharyngitis.
van Driel ML, De Sutter AI, Thorning S, Christiaens T
Cochrane Database Syst Rev 2021 Mar 17;3(3):CD004406. doi: 10.1002/14651858.CD004406.pub5. PMID: 33728634Free PMC Article
Different antibiotic treatments for group A streptococcal pharyngitis.
van Driel ML, De Sutter AI, Keber N, Habraken H, Christiaens T
Cochrane Database Syst Rev 2013 Apr 30;(4):CD004406. doi: 10.1002/14651858.CD004406.pub3. PMID: 23633318

Supplemental Content

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    Practice guidelines

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