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Peak A Velocity

MedGen UID:
925952
•Concept ID:
C4288420
•
Finding

Definition

The maximum rate of blood flow across a cardiac valve during late diastole (active ventricular filling). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeak A Velocity

Professional guidelines

PubMed

Clinical utility of ductus venosus flow in fetuses with right-sided congenital heart disease.
Arya B, Krishnan A, Donofrio MT
J Ultrasound Med 2014 Sep;33(9):1563-71. doi: 10.7863/ultra.33.9.1563. PMID: 25154936

Recent clinical studies

Etiology

Is non-alcoholic fatty liver disease a sign of left ventricular diastolic dysfunction in patients with type 2 diabetes mellitus? A systematic review and meta-analysis.
Wang S, Zhang X, Zhang Q, Zhang B, Zhao L
BMJ Open Diabetes Res Care 2023 Feb;11(1) doi: 10.1136/bmjdrc-2022-003198. PMID: 36807034Free PMC Article
To determine the correlation between echocardiographic diastolic parameters and invasively measured left ventricular end diastolic pressure in patients with heart failure with preserved ejection fraction- an observational, descriptive study. (CEAL-HFpEF study).
Sharma AK, Kumar H, Razi MM, Sinha SK, Pandey U, Shukla P, Thakur R, Verma CM, Bansal RK, Krishna V
Indian Heart J 2021 Jul-Aug;73(4):470-475. Epub 2021 Jul 6 doi: 10.1016/j.ihj.2021.06.012. PMID: 34474760Free PMC Article
Assessment of atrial functional remodeling in patients with atrioventricular nodal reentrant tachycardia with and without drug-induced type 1 Brugada pattern: A case-control study.
Kocabaş U, Payzın S, Hasdemir C
J Clin Ultrasound 2021 Jul;49(6):573-579. Epub 2021 Feb 18 doi: 10.1002/jcu.22990. PMID: 33599988
Increased atrial contraction contribution to left ventricular filling during early septic shock.
Monge García MI, Del Rio Lechuga A, Fletcher N, Gil Cano A
J Crit Care 2019 Dec;54:220-227. Epub 2019 Sep 11 doi: 10.1016/j.jcrc.2019.09.006. PMID: 31630070
Insulin resistance and risk of incident heart failure: Cardiovascular Health Study.
Banerjee D, Biggs ML, Mercer L, Mukamal K, Kaplan R, Barzilay J, Kuller L, Kizer JR, Djousse L, Tracy R, Zieman S, Lloyd-Jones D, Siscovick D, Carnethon M
Circ Heart Fail 2013 May;6(3):364-70. Epub 2013 Apr 10 doi: 10.1161/CIRCHEARTFAILURE.112.000022. PMID: 23575256Free PMC Article

Diagnosis

To determine the correlation between echocardiographic diastolic parameters and invasively measured left ventricular end diastolic pressure in patients with heart failure with preserved ejection fraction- an observational, descriptive study. (CEAL-HFpEF study).
Sharma AK, Kumar H, Razi MM, Sinha SK, Pandey U, Shukla P, Thakur R, Verma CM, Bansal RK, Krishna V
Indian Heart J 2021 Jul-Aug;73(4):470-475. Epub 2021 Jul 6 doi: 10.1016/j.ihj.2021.06.012. PMID: 34474760Free PMC Article
Improvements in cardiac function detected using echocardiography in patients with hereditary haemochromatosis.
Byrne D, Walsh JP, Daly C, McKiernan S, Norris S, Murphy RT, King G
Ir J Med Sci 2020 Feb;189(1):109-117. Epub 2019 May 20 doi: 10.1007/s11845-019-02032-5. PMID: 31111347
Insulin resistance and risk of incident heart failure: Cardiovascular Health Study.
Banerjee D, Biggs ML, Mercer L, Mukamal K, Kaplan R, Barzilay J, Kuller L, Kizer JR, Djousse L, Tracy R, Zieman S, Lloyd-Jones D, Siscovick D, Carnethon M
Circ Heart Fail 2013 May;6(3):364-70. Epub 2013 Apr 10 doi: 10.1161/CIRCHEARTFAILURE.112.000022. PMID: 23575256Free PMC Article
Doppler characteristics of late-diastolic flow in the left ventricular outflow tract.
Jaeger KM, Rahko PS
J Am Soc Echocardiogr 1990 May-Jun;3(3):179-86. doi: 10.1016/s0894-7317(14)80432-x. PMID: 2372400
Echocardiographic and Doppler evaluation of left ventricular hypertrophy and diastolic function in black and white hypertensive patients.
Rittoo D, Monaghan M, Sadiq T, Nichols A, Richardson PJ
J Hum Hypertens 1990 Apr;4(2):113-5. PMID: 2140134

Therapy

Is non-alcoholic fatty liver disease a sign of left ventricular diastolic dysfunction in patients with type 2 diabetes mellitus? A systematic review and meta-analysis.
Wang S, Zhang X, Zhang Q, Zhang B, Zhao L
BMJ Open Diabetes Res Care 2023 Feb;11(1) doi: 10.1136/bmjdrc-2022-003198. PMID: 36807034Free PMC Article
Effect of Levothyroxine Supplementation on the Cardiac Morphology and Function in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis.
Wang X, Wang H, Li Q, Wang P, Xing Y, Zhang F, Li J, Shan Z
J Clin Endocrinol Metab 2022 Aug 18;107(9):2674-2683. doi: 10.1210/clinem/dgac417. PMID: 35810404
Insulin resistance and risk of incident heart failure: Cardiovascular Health Study.
Banerjee D, Biggs ML, Mercer L, Mukamal K, Kaplan R, Barzilay J, Kuller L, Kizer JR, Djousse L, Tracy R, Zieman S, Lloyd-Jones D, Siscovick D, Carnethon M
Circ Heart Fail 2013 May;6(3):364-70. Epub 2013 Apr 10 doi: 10.1161/CIRCHEARTFAILURE.112.000022. PMID: 23575256Free PMC Article
Left atrial systolic force in hypertensive patients with left ventricular hypertrophy: the LIFE study.
Chinali M, de Simone G, Wachtell K, Gerdts E, Gardin JM, Boman K, Nieminen MS, Papademetriou V, Dahlöf B, Devereux RB
J Hypertens 2008 Jul;26(7):1472-6. doi: 10.1097/HJH.0b013e3282ff84d7. PMID: 18551025
The short-term effects of cilazapril on left ventricular diastolic function.
Koylan N, Oncül A, Mercanoğlu F, Orak E, Erzengin F, Büyüköztürk K
J Cardiovasc Pharmacol 1994;24 Suppl 3:S42-4. PMID: 7700064

Prognosis

Improvements in cardiac function detected using echocardiography in patients with hereditary haemochromatosis.
Byrne D, Walsh JP, Daly C, McKiernan S, Norris S, Murphy RT, King G
Ir J Med Sci 2020 Feb;189(1):109-117. Epub 2019 May 20 doi: 10.1007/s11845-019-02032-5. PMID: 31111347
Insulin resistance and risk of incident heart failure: Cardiovascular Health Study.
Banerjee D, Biggs ML, Mercer L, Mukamal K, Kaplan R, Barzilay J, Kuller L, Kizer JR, Djousse L, Tracy R, Zieman S, Lloyd-Jones D, Siscovick D, Carnethon M
Circ Heart Fail 2013 May;6(3):364-70. Epub 2013 Apr 10 doi: 10.1161/CIRCHEARTFAILURE.112.000022. PMID: 23575256Free PMC Article
Echocardiographic evaluation of left atrial size and function: current understanding, pathophysiologic correlates, and prognostic implications.
Leung DY, Boyd A, Ng AA, Chi C, Thomas L
Am Heart J 2008 Dec;156(6):1056-64. Epub 2008 Oct 2 doi: 10.1016/j.ahj.2008.07.021. PMID: 19032999
Left atrial systolic force in hypertensive patients with left ventricular hypertrophy: the LIFE study.
Chinali M, de Simone G, Wachtell K, Gerdts E, Gardin JM, Boman K, Nieminen MS, Papademetriou V, Dahlöf B, Devereux RB
J Hypertens 2008 Jul;26(7):1472-6. doi: 10.1097/HJH.0b013e3282ff84d7. PMID: 18551025
Left ventricular diastolic filling performance in older male athletes.
Fleg JL, Shapiro EP, O'Connor F, Taube J, Goldberg AP, Lakatta EG
JAMA 1995 May 3;273(17):1371-5. PMID: 7715063

Clinical prediction guides

Is non-alcoholic fatty liver disease a sign of left ventricular diastolic dysfunction in patients with type 2 diabetes mellitus? A systematic review and meta-analysis.
Wang S, Zhang X, Zhang Q, Zhang B, Zhao L
BMJ Open Diabetes Res Care 2023 Feb;11(1) doi: 10.1136/bmjdrc-2022-003198. PMID: 36807034Free PMC Article
To determine the correlation between echocardiographic diastolic parameters and invasively measured left ventricular end diastolic pressure in patients with heart failure with preserved ejection fraction- an observational, descriptive study. (CEAL-HFpEF study).
Sharma AK, Kumar H, Razi MM, Sinha SK, Pandey U, Shukla P, Thakur R, Verma CM, Bansal RK, Krishna V
Indian Heart J 2021 Jul-Aug;73(4):470-475. Epub 2021 Jul 6 doi: 10.1016/j.ihj.2021.06.012. PMID: 34474760Free PMC Article
Echocardiographic findings before and after surgical repair of Tetralogy of Fallot.
Noori NM, Mahjoubifard M, Alavi SM, Teimouri A
J Pak Med Assoc 2015 Sep;65(9):921-7. PMID: 26338733
Systolic and diastolic function in patients with systemic sclerosis.
Poanta L, Dadu R, Tiboc C, Rednic S, Dumitrascu D
Eur J Intern Med 2009 Jul;20(4):378-82. Epub 2008 Nov 29 doi: 10.1016/j.ejim.2008.10.011. PMID: 19524178
Left atrial systolic force and cardiovascular outcome. The Strong Heart Study.
Chinali M, de Simone G, Roman MJ, Bella JN, Liu JE, Lee ET, Best LG, Howard BV, Devereux RB
Am J Hypertens 2005 Dec;18(12 Pt 1):1570-6; discussion 1577. doi: 10.1016/j.amjhyper.2005.05.036. PMID: 16364827

Recent systematic reviews

Is non-alcoholic fatty liver disease a sign of left ventricular diastolic dysfunction in patients with type 2 diabetes mellitus? A systematic review and meta-analysis.
Wang S, Zhang X, Zhang Q, Zhang B, Zhao L
BMJ Open Diabetes Res Care 2023 Feb;11(1) doi: 10.1136/bmjdrc-2022-003198. PMID: 36807034Free PMC Article
Effect of Levothyroxine Supplementation on the Cardiac Morphology and Function in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis.
Wang X, Wang H, Li Q, Wang P, Xing Y, Zhang F, Li J, Shan Z
J Clin Endocrinol Metab 2022 Aug 18;107(9):2674-2683. doi: 10.1210/clinem/dgac417. PMID: 35810404

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