U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Gingival Spindle Cell Carcinoma

MedGen UID:
926567
Concept ID:
C4289035
Neoplastic Process

Definition

A poorly differentiated squamous cell carcinoma that arises from the gingiva. It is characterized by the presence of malignant pleomorphic spindle cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGingival Spindle Cell Carcinoma

Professional guidelines

PubMed

Górski B
Int J Environ Res Public Health 2022 Jul 9;19(14) doi: 10.3390/ijerph19148397. PMID: 35886246Free PMC Article
Arduino PG, Carbone M, Gambino A, Cabras M, Cannarsa F, Macciotta A, Conrotto D, Broccoletti R
Med Oral Patol Oral Cir Bucal 2021 Jan 1;26(1):e21-e27. doi: 10.4317/medoral.23913. PMID: 32851989Free PMC Article
Misra S, Chaturvedi A, Misra NC
Ann R Coll Surg Engl 2008 Oct;90(7):546-53. Epub 2008 Aug 12 doi: 10.1308/003588408X301136. PMID: 18701010Free PMC Article

Recent clinical studies

Etiology

Li Y, Tan X, Zhao X, Xu Z, Dai W, Duan W, Huang S, Zhang E, Liu J, Zhang S, Yin R, Shi X, Lu Z, Pan Y
Oral Oncol 2020 Aug;107:104710. Epub 2020 May 3 doi: 10.1016/j.oraloncology.2020.104710. PMID: 32371264
Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, Geisinger ML, Genco RJ, Glogauer M, Goldstein M, Griffin TJ, Holmstrup P, Johnson GK, Kapila Y, Lang NP, Meyle J, Murakami S, Plemons J, Romito GA, Shapira L, Tatakis DN, Teughels W, Trombelli L, Walter C, Wimmer G, Xenoudi P, Yoshie H
J Periodontol 2018 Jun;89 Suppl 1:S74-S84. doi: 10.1002/JPER.17-0719. PMID: 29926944
Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, Geisinger ML, Genco RJ, Glogauer M, Goldstein M, Griffin TJ, Holmstrup P, Johnson GK, Kapila Y, Lang NP, Meyle J, Murakami S, Plemons J, Romito GA, Shapira L, Tatakis DN, Teughels W, Trombelli L, Walter C, Wimmer G, Xenoudi P, Yoshie H
J Clin Periodontol 2018 Jun;45 Suppl 20:S68-S77. doi: 10.1111/jcpe.12940. PMID: 29926499
Kaplan I, Zeevi I, Tal H, Rosenfeld E, Chaushu G
Oral Surg Oral Med Oral Pathol Oral Radiol 2017 Jan;123(1):103-112. Epub 2016 Sep 9 doi: 10.1016/j.oooo.2016.08.023. PMID: 27720649
Agha-Hosseini F, Rohani B
J Contemp Dent Pract 2015 May 1;16(5):400-6. doi: 10.5005/jp-journals-10024-1697. PMID: 26162261

Diagnosis

Tchernev G, Kandathil LJ, Oliveira N
Wien Med Wochenschr 2023 Sep;173(11-12):249-250. Epub 2021 Nov 4 doi: 10.1007/s10354-021-00894-y. PMID: 34735668
Schuch LF, Schmidt TR, de Oliveira Zigmundo G, Kirschnick LB, Silveira FM, Martins MAT, Carlos R, Dos Santos JN, Fonseca FP, Vargas PA, Wagner VP, Martins MD
Head Neck Pathol 2022 Jun;16(2):525-537. Epub 2021 Dec 6 doi: 10.1007/s12105-021-01398-2. PMID: 34870796Free PMC Article
Khurshid Z, Zafar MS, Khan RS, Najeeb S, Slowey PD, Rehman IU
Adv Clin Chem 2018;86:23-70. Epub 2018 Jul 23 doi: 10.1016/bs.acc.2018.05.002. PMID: 30144841
Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, Geisinger ML, Genco RJ, Glogauer M, Goldstein M, Griffin TJ, Holmstrup P, Johnson GK, Kapila Y, Lang NP, Meyle J, Murakami S, Plemons J, Romito GA, Shapira L, Tatakis DN, Teughels W, Trombelli L, Walter C, Wimmer G, Xenoudi P, Yoshie H
J Periodontol 2018 Jun;89 Suppl 1:S74-S84. doi: 10.1002/JPER.17-0719. PMID: 29926944
Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, Geisinger ML, Genco RJ, Glogauer M, Goldstein M, Griffin TJ, Holmstrup P, Johnson GK, Kapila Y, Lang NP, Meyle J, Murakami S, Plemons J, Romito GA, Shapira L, Tatakis DN, Teughels W, Trombelli L, Walter C, Wimmer G, Xenoudi P, Yoshie H
J Clin Periodontol 2018 Jun;45 Suppl 20:S68-S77. doi: 10.1111/jcpe.12940. PMID: 29926499

Therapy

Sindoni A, Valeriani F, Protano C, Liguori G, Romano Spica V, Vitali M, Gallè F
Public Health 2022 Apr;205:202-215. Epub 2022 Mar 24 doi: 10.1016/j.puhe.2022.01.035. PMID: 35339940
Barbieri S, Schuch LF, Cascaes AM, Gomes APN, Tarquinio SBC, Mesquita RA, Vasconcelos ACU, Etges A
Braz Oral Res 2022;36:e044. Epub 2022 Mar 14 doi: 10.1590/1807-3107bor-2022.vol36.0044. PMID: 35293509
Kaplan I, Zeevi I, Tal H, Rosenfeld E, Chaushu G
Oral Surg Oral Med Oral Pathol Oral Radiol 2017 Jan;123(1):103-112. Epub 2016 Sep 9 doi: 10.1016/j.oooo.2016.08.023. PMID: 27720649
Agha-Hosseini F, Rohani B
J Contemp Dent Pract 2015 May 1;16(5):400-6. doi: 10.5005/jp-journals-10024-1697. PMID: 26162261
Mandl I
Science 1970 Sep 18;169(3951):1234-8. doi: 10.1126/science.169.3951.1234. PMID: 4317926

Prognosis

Sang L, Dai Y, Hu J, Zhu Y, Xu L, Zhang W, Cheng J
Oral Dis 2023 Mar;29(2):686-695. Epub 2021 Oct 7 doi: 10.1111/odi.14037. PMID: 34592043
Schuch LF, Schmidt TR, de Oliveira Zigmundo G, Kirschnick LB, Silveira FM, Martins MAT, Carlos R, Dos Santos JN, Fonseca FP, Vargas PA, Wagner VP, Martins MD
Head Neck Pathol 2022 Jun;16(2):525-537. Epub 2021 Dec 6 doi: 10.1007/s12105-021-01398-2. PMID: 34870796Free PMC Article
Li Y, Tan X, Zhao X, Xu Z, Dai W, Duan W, Huang S, Zhang E, Liu J, Zhang S, Yin R, Shi X, Lu Z, Pan Y
Oral Oncol 2020 Aug;107:104710. Epub 2020 May 3 doi: 10.1016/j.oraloncology.2020.104710. PMID: 32371264
Khurshid Z, Zafar MS, Khan RS, Najeeb S, Slowey PD, Rehman IU
Adv Clin Chem 2018;86:23-70. Epub 2018 Jul 23 doi: 10.1016/bs.acc.2018.05.002. PMID: 30144841
Zhang WB, Peng X
Head Neck 2016 Apr;38 Suppl 1:E2335-42. Epub 2016 Feb 18 doi: 10.1002/hed.24274. PMID: 26890607

Clinical prediction guides

Yamazaki M, Maruyama S, Abé T, Sumita Y, Katsumi Y, Nikkuni Y, Hayashi T, Tanuma JI
J Med Case Rep 2021 Aug 27;15(1):438. doi: 10.1186/s13256-021-03066-z. PMID: 34452644Free PMC Article
Li Y, Tan X, Zhao X, Xu Z, Dai W, Duan W, Huang S, Zhang E, Liu J, Zhang S, Yin R, Shi X, Lu Z, Pan Y
Oral Oncol 2020 Aug;107:104710. Epub 2020 May 3 doi: 10.1016/j.oraloncology.2020.104710. PMID: 32371264
Takahashi H, Watanabe M, Ohyama A, Toyomura J, Tachibana T, Tanaka A, Ishikawa H
Hum Cell 2019 Jan;32(1):75-82. Epub 2018 Aug 31 doi: 10.1007/s13577-018-0216-z. PMID: 30171458
Fu X, Chen S, Chen W, Yang Z, Song M, Li H, Zhang H, Yao F, Su X, Liu T, Yang AK
Oral Oncol 2018 Sep;84:20-24. Epub 2018 Jun 30 doi: 10.1016/j.oraloncology.2018.06.018. PMID: 30115471
Zhang WB, Peng X
Head Neck 2016 Apr;38 Suppl 1:E2335-42. Epub 2016 Feb 18 doi: 10.1002/hed.24274. PMID: 26890607

Recent systematic reviews

de la Fuente C, Prat-Valero N, Alberola-Ferranti M, Mis-Castell D, Sáez-Barba M, Pujol-Pina R, Pamias-Romero J, Bescós-Atín C
Head Neck 2023 Mar;45(3):733-744. Epub 2022 Dec 14 doi: 10.1002/hed.27276. PMID: 36515647
Sindoni A, Valeriani F, Protano C, Liguori G, Romano Spica V, Vitali M, Gallè F
Public Health 2022 Apr;205:202-215. Epub 2022 Mar 24 doi: 10.1016/j.puhe.2022.01.035. PMID: 35339940
Schuch LF, Schmidt TR, de Oliveira Zigmundo G, Kirschnick LB, Silveira FM, Martins MAT, Carlos R, Dos Santos JN, Fonseca FP, Vargas PA, Wagner VP, Martins MD
Head Neck Pathol 2022 Jun;16(2):525-537. Epub 2021 Dec 6 doi: 10.1007/s12105-021-01398-2. PMID: 34870796Free PMC Article
Tang L, Leung YY
Int J Oral Maxillofac Surg 2016 Nov;45(11):1358-1365. Epub 2016 Jun 8 doi: 10.1016/j.ijom.2016.05.021. PMID: 27289248
Zhang WB, Peng X
Head Neck 2016 Apr;38 Suppl 1:E2335-42. Epub 2016 Feb 18 doi: 10.1002/hed.24274. PMID: 26890607

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...