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Renal cortical necrosis

MedGen UID:
9634
•Concept ID:
C0022656
•
Disease or Syndrome
Synonym: Kidney cortex necrosis
SNOMED CT: Necrosis of cortex of kidney (444691002); Renal cortical necrosis (444691002)
 
HPO: HP:0025418
Monarch Initiative: MONDO:0006820

Definition

Patchy or diffuse ischemic destruction of all the elements of renal cortex resulting from significantly diminished renal arterial perfusion. Coagulative necrosis may be present, involving all tubular segments and glomeruli. Nuclei may be pale and pyknotic, or may no longer be apparent. Thrombi may be present in vessels at the edge of the infarct. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRenal cortical necrosis

Professional guidelines

PubMed

Differential diagnosis between organic and inorganic mercury poisoning in human cases--the pathologic point of view.
Eto K, Takizawa Y, Akagi H, Haraguchi K, Asano S, Takahata N, Tokunaga H
Toxicol Pathol 1999 Nov-Dec;27(6):664-71. doi: 10.1177/019262339902700608. PMID: 10588547
Severe twin-twin transfusion syndrome: current management concepts.
Dickinson JE
Aust N Z J Obstet Gynaecol 1995 Feb;35(1):16-21. doi: 10.1111/j.1479-828x.1995.tb01823.x. PMID: 7771992
Bilateral renal cortical necrosis in the newborn infant: roentgenographic diagnosis.
Leonidas JC, Berdon WE, Gribetz D
J Pediatr 1971 Oct;79(4):623-7. doi: 10.1016/s0022-3476(71)80310-4. PMID: 5094257

Recent clinical studies

Etiology

Bilateral acute renal cortical necrosis after a dog bite: case report.
Amacher SA, Søgaard KK, Nkoulou C, Sutter R, Weisser M, Zingg SS, Egli A, Hollinger A, Siegemund M
BMC Infect Dis 2021 Feb 27;21(1):231. doi: 10.1186/s12879-021-05901-6. PMID: 33639872Free PMC Article
Renal Cortical Necrosis; Five Consecutive Cases within Short Span of Time.
Jaynul Islam SM, Akhter S, Hossain MS
Saudi J Kidney Dis Transpl 2019 Jul-Aug;30(4):919-923. doi: 10.4103/1319-2442.265469. PMID: 31464250
Renal Cortical Necrosis in Postpartum Hemorrhage: A Case Series.
Frimat M, Decambron M, Lebas C, Moktefi A, Lemaitre L, Gnemmi V, Sautenet B, Glowacki F, Subtil D, Jourdain M, Rigouzzo A, Brocheriou I, Halimi JM, Rondeau E, Noel C, Provôt F, Hertig A
Am J Kidney Dis 2016 Jul;68(1):50-7. Epub 2016 Jan 16 doi: 10.1053/j.ajkd.2015.11.022. PMID: 26786299
Renal cortical necrosis: a case series of nine patients & review of literature.
Ali SS, Rizvi SZ, Muzaffar S, Ahmad A, Ali A, Hassan SH
J Ayub Med Coll Abbottabad 2003 Apr-Jun;15(2):41-4. PMID: 14552248
Traumatic bilateral renal infarction.
Peterson NE
J Trauma 1989 Feb;29(2):158-67. PMID: 2645409

Diagnosis

A Pictorial Review of Postpartum Complications.
Gonzalo-Carballes M, Ríos-Vives MÁ, Fierro EC, Azogue XG, Herrero SG, Rodríguez AE, Rus MN, Planes-Conangla M, Escudero-Fernandez JM, Coscojuela P
Radiographics 2020 Nov-Dec;40(7):2117-2141. Epub 2020 Oct 23 doi: 10.1148/rg.2020200031. PMID: 33095681
Renal Cortical Necrosis; Five Consecutive Cases within Short Span of Time.
Jaynul Islam SM, Akhter S, Hossain MS
Saudi J Kidney Dis Transpl 2019 Jul-Aug;30(4):919-923. doi: 10.4103/1319-2442.265469. PMID: 31464250
Renal cortical necrosis in tropics.
Sahay M; Swarnalata, Swain M, Padua M
Saudi J Kidney Dis Transpl 2013 Jul;24(4):725-30. doi: 10.4103/1319-2442.113864. PMID: 23816721
Acute renal failure in pregnancy.
Pertuiset N, Grünfeld JP
Baillieres Clin Obstet Gynaecol 1994 Jun;8(2):333-51. doi: 10.1016/s0950-3552(05)80324-4. PMID: 7924011
Traumatic bilateral renal infarction.
Peterson NE
J Trauma 1989 Feb;29(2):158-67. PMID: 2645409

Therapy

Bilateral acute renal cortical necrosis after a dog bite: case report.
Amacher SA, Søgaard KK, Nkoulou C, Sutter R, Weisser M, Zingg SS, Egli A, Hollinger A, Siegemund M
BMC Infect Dis 2021 Feb 27;21(1):231. doi: 10.1186/s12879-021-05901-6. PMID: 33639872Free PMC Article
Multiparametric ultrasound findings in acute kidney failure due to rare renal cortical necrosis.
Spiesecke P, Münch F, Fischer T, Hamm B, Lerchbaumer MH
Sci Rep 2021 Jan 21;11(1):2060. doi: 10.1038/s41598-021-81690-x. PMID: 33479443Free PMC Article
Renal ischemic adverse drug events related to tranexamic acid in women of child-bearing age: an analysis of pharmacovigilance data.
Stämpfli D, Weiler S, Weiniger CF, Burden AM, Heesen M
Eur J Clin Pharmacol 2021 Jun;77(6):913-919. Epub 2020 Dec 19 doi: 10.1007/s00228-020-03064-y. PMID: 33341923Free PMC Article
Changing epidemiology of acute kidney injury in pregnancy: A journey of four decades from a developing country.
Prakash J, Prakash S, Ganiger VC
Saudi J Kidney Dis Transpl 2019 Sep-Oct;30(5):1118-1130. doi: 10.4103/1319-2442.270268. PMID: 31696851
The defibrination syndrome.
Lerner RG
Med Clin North Am 1976 Sep;60(5):871-80. doi: 10.1016/s0025-7125(16)31837-5. PMID: 781414

Prognosis

Bilateral acute renal cortical necrosis after a dog bite: case report.
Amacher SA, Søgaard KK, Nkoulou C, Sutter R, Weisser M, Zingg SS, Egli A, Hollinger A, Siegemund M
BMC Infect Dis 2021 Feb 27;21(1):231. doi: 10.1186/s12879-021-05901-6. PMID: 33639872Free PMC Article
Acute renal cortical necrosis in pregnancy: Clinical course and changing prognosis.
Beji S, Hajji M, Rais L, Kheder R, Jebali H, Smaoui W, Krid M, Ben Hamida F, Ben Fatma L, Zouaghi MK
Nephrol Ther 2017 Dec;13(7):550-552. doi: 10.1016/j.nephro.2016.10.007. PMID: 29100716
Renal cortical necrosis: a case series of nine patients & review of literature.
Ali SS, Rizvi SZ, Muzaffar S, Ahmad A, Ali A, Hassan SH
J Ayub Med Coll Abbottabad 2003 Apr-Jun;15(2):41-4. PMID: 14552248
Acute renal failure in pregnancy: 1987.
Grünfeld JP, Pertuiset N
Am J Kidney Dis 1987 Apr;9(4):359-62. doi: 10.1016/s0272-6386(87)80137-3. PMID: 3555010
Acute renal cortical necrosis. Variable course and changing prognosis.
Bloom R, Swenson RS, Coplon NS
Calif Med 1973 Oct;119(4):1-5. PMID: 4749308Free PMC Article

Clinical prediction guides

Changing epidemiology of acute kidney injury in pregnancy: A journey of four decades from a developing country.
Prakash J, Prakash S, Ganiger VC
Saudi J Kidney Dis Transpl 2019 Sep-Oct;30(5):1118-1130. doi: 10.4103/1319-2442.270268. PMID: 31696851
Acute cortical necrosis in pregnancy still an important cause for end-stage renal disease in developing countries.
Bhaduaria D, Kaul A, Lal H, Mishra P, Jain M, Prasad N, Pradhan M, Patel MR, Gupta A, Sharma RK
Saudi J Kidney Dis Transpl 2019 Mar-Apr;30(2):325-333. doi: 10.4103/1319-2442.256839. PMID: 31031368
Acute kidney injury in pregnancy--a single center experience.
Gopalakrishnan N, Dhanapriya J, Muthukumar P, Sakthirajan R, Dineshkumar T, Thirumurugan S, Balasubramaniyan T
Ren Fail 2015;37(9):1476-80. Epub 2015 Sep 3 doi: 10.3109/0886022X.2015.1074493. PMID: 26338215
Renal cortical necrosis is a disappearing entity in obstetric acute kidney injury in developing countries: our three decade of experience from India.
Prakash J, Pant P, Singh AK, Sriniwas S, Singh VP, Singh U
Ren Fail 2015 Aug;37(7):1185-9. Epub 2015 Jul 2 doi: 10.3109/0886022X.2015.1062340. PMID: 26133740
Traumatic bilateral renal infarction.
Peterson NE
J Trauma 1989 Feb;29(2):158-67. PMID: 2645409

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