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Benign Extrahepatic Bile Duct Neoplasm

MedGen UID:
96925
Concept ID:
C0496871
Neoplastic Process
Synonyms: Benign Extrahepatic Bile Duct Tumor; Benign Neoplasm of Extrahepatic Bile Duct; Benign neoplasm of extrahepatic bile ducts; Benign Neoplasm of the Extrahepatic Bile Duct; Benign tumor of extrahepatic bile duct; Benign Tumor of Extrahepatic Bile Duct; Benign Tumor of the Extrahepatic Bile Duct
SNOMED CT: Benign tumor of extrahepatic bile duct (92096008); Benign neoplasm of extrahepatic bile ducts (92096008)

Definition

A neoplasm that arises from the extrahepatic bile ducts and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

Dumonceau JM, Tringali A, Papanikolaou IS, Blero D, Mangiavillano B, Schmidt A, Vanbiervliet G, Costamagna G, Devière J, García-Cano J, Gyökeres T, Hassan C, Prat F, Siersema PD, van Hooft JE
Endoscopy 2018 Sep;50(9):910-930. Epub 2018 Aug 7 doi: 10.1055/a-0659-9864. PMID: 30086596
Tabibian JH, Baron TH
Expert Rev Gastroenterol Hepatol 2018 Jul;12(7):693-703. Epub 2018 Jun 18 doi: 10.1080/17474124.2018.1483719. PMID: 29883229
Larghi A, Tringali A, Lecca PG, Giordano M, Costamagna G
Am J Gastroenterol 2008 Feb;103(2):458-73. Epub 2007 Nov 19 doi: 10.1111/j.1572-0241.2007.01645.x. PMID: 18028506

Recent clinical studies

Etiology

Wang M, Li D, Chen R, Huang X, Li J, Liu Y, Liu J, Cheng W, Chen X, Zhao W, Li J, Tan Z, Huang H, Li D, Zhu F, Qin T, Ma J, Yu G, Zhou B, Zheng S, Tang Y, Han W, Meng L, Ke J, Feng F, Chen B, Yin X, Chen W, Ma H, Xu J, Liu Y, Lin R, Dong Y, Yu Y, Liu J, Zhang H, Qin R; Minimally Invasive Treatment Group in the Pancreatic Disease Branch of China's International Exchange and Promotion Association for Medicine and Healthcare (MITG-P-CPAM)
Lancet Gastroenterol Hepatol 2021 Jun;6(6):438-447. Epub 2021 Apr 27 doi: 10.1016/S2468-1253(21)00054-6. PMID: 33915091
Fung BM, Tabibian JH
Curr Opin Gastroenterol 2020 Mar;36(2):77-84. doi: 10.1097/MOG.0000000000000616. PMID: 31850928
Tabibian JH, Baron TH
Expert Rev Gastroenterol Hepatol 2018 Jul;12(7):693-703. Epub 2018 Jun 18 doi: 10.1080/17474124.2018.1483719. PMID: 29883229
Liu X, Yang Z, Tan H, Shao C, Liu L, Si S, Xu L, Sun Y
J Surg Res 2016 Jun 15;203(2):275-82. Epub 2016 Mar 25 doi: 10.1016/j.jss.2016.03.002. PMID: 27363632
Biswas PK
Mymensingh Med J 2010 Jul;19(3):477-81. PMID: 20639849

Diagnosis

Fung BM, Tabibian JH
Curr Opin Gastroenterol 2020 Mar;36(2):77-84. doi: 10.1097/MOG.0000000000000616. PMID: 31850928
Tabibian JH, Baron TH
Expert Rev Gastroenterol Hepatol 2018 Jul;12(7):693-703. Epub 2018 Jun 18 doi: 10.1080/17474124.2018.1483719. PMID: 29883229
Nikolaidis P, Hammond NA, Day K, Yaghmai V, Wood CG 3rd, Mosbach DS, Harmath CB, Taffel MT, Horowitz JM, Berggruen SM, Miller FH
Radiographics 2014 May-Jun;34(3):624-41. doi: 10.1148/rg.343125191. PMID: 24819785
Katabathina VS, Dasyam AK, Dasyam N, Hosseinzadeh K
Radiographics 2014 May-Jun;34(3):565-86. doi: 10.1148/rg.343125211. PMID: 24819781
Biswas PK
Mymensingh Med J 2010 Jul;19(3):477-81. PMID: 20639849

Therapy

Wang M, Li D, Chen R, Huang X, Li J, Liu Y, Liu J, Cheng W, Chen X, Zhao W, Li J, Tan Z, Huang H, Li D, Zhu F, Qin T, Ma J, Yu G, Zhou B, Zheng S, Tang Y, Han W, Meng L, Ke J, Feng F, Chen B, Yin X, Chen W, Ma H, Xu J, Liu Y, Lin R, Dong Y, Yu Y, Liu J, Zhang H, Qin R; Minimally Invasive Treatment Group in the Pancreatic Disease Branch of China's International Exchange and Promotion Association for Medicine and Healthcare (MITG-P-CPAM)
Lancet Gastroenterol Hepatol 2021 Jun;6(6):438-447. Epub 2021 Apr 27 doi: 10.1016/S2468-1253(21)00054-6. PMID: 33915091
Li W, Jiang F, Li X, Li H, Zheng Z
Int J Immunopathol Pharmacol 2020 Jan-Dec;34:2058738420941752. doi: 10.1177/2058738420941752. PMID: 32684063Free PMC Article
Tabibian JH, Baron TH
Expert Rev Gastroenterol Hepatol 2018 Jul;12(7):693-703. Epub 2018 Jun 18 doi: 10.1080/17474124.2018.1483719. PMID: 29883229
Gholami S, Brennan MF
Surg Clin North Am 2018 Feb;98(1):37-47. doi: 10.1016/j.suc.2017.09.005. PMID: 29191276Free PMC Article
De Palma GD
World J Gastroenterol 2014 Feb 14;20(6):1537-43. doi: 10.3748/wjg.v20.i6.1537. PMID: 24587629Free PMC Article

Prognosis

Taliente F, Bianco G, Moschetta G, Franco A, Giovinazzo F, Agnes S, Spoletini G
Chin Clin Oncol 2022 Jun;11(3):23. doi: 10.21037/cco-21-141. PMID: 35818855
Xu S, Huang S, Li D, Zou Q, Yuan Y, Yang Z
Am J Med Sci 2022 Aug;364(2):181-191. Epub 2021 Nov 18 doi: 10.1016/j.amjms.2021.11.004. PMID: 34800429
Fung BM, Tabibian JH
Curr Opin Gastroenterol 2020 Mar;36(2):77-84. doi: 10.1097/MOG.0000000000000616. PMID: 31850928
Tabibian JH, Baron TH
Expert Rev Gastroenterol Hepatol 2018 Jul;12(7):693-703. Epub 2018 Jun 18 doi: 10.1080/17474124.2018.1483719. PMID: 29883229
Biswas PK
Mymensingh Med J 2010 Jul;19(3):477-81. PMID: 20639849

Clinical prediction guides

Wang M, Li D, Chen R, Huang X, Li J, Liu Y, Liu J, Cheng W, Chen X, Zhao W, Li J, Tan Z, Huang H, Li D, Zhu F, Qin T, Ma J, Yu G, Zhou B, Zheng S, Tang Y, Han W, Meng L, Ke J, Feng F, Chen B, Yin X, Chen W, Ma H, Xu J, Liu Y, Lin R, Dong Y, Yu Y, Liu J, Zhang H, Qin R; Minimally Invasive Treatment Group in the Pancreatic Disease Branch of China's International Exchange and Promotion Association for Medicine and Healthcare (MITG-P-CPAM)
Lancet Gastroenterol Hepatol 2021 Jun;6(6):438-447. Epub 2021 Apr 27 doi: 10.1016/S2468-1253(21)00054-6. PMID: 33915091
Li W, Jiang F, Li X, Li H, Zheng Z
Int J Immunopathol Pharmacol 2020 Jan-Dec;34:2058738420941752. doi: 10.1177/2058738420941752. PMID: 32684063Free PMC Article
Tabibian JH, Baron TH
Expert Rev Gastroenterol Hepatol 2018 Jul;12(7):693-703. Epub 2018 Jun 18 doi: 10.1080/17474124.2018.1483719. PMID: 29883229
Ohtsuka M, Kimura F, Shimizu H, Yoshidome H, Kato A, Yoshitomi H, Furukawa K, Mitsuhashi N, Takeuchi D, Takayashiki T, Suda K, Miyazaki M
J Hepatobiliary Pancreat Sci 2010 May;17(3):236-40. Epub 2009 Aug 1 doi: 10.1007/s00534-009-0152-0. PMID: 19649559
Gertsch P, Thomas P, Baer H, Lerut J, Zimmermann A, Blumgart LH
Am J Surg 1990 Apr;159(4):386-8. doi: 10.1016/s0002-9610(05)81278-4. PMID: 2180336

Recent systematic reviews

Garg R, Thind K, Bhalla J, Simonson MT, Simons-Linares CR, Singh A, Joyce D, Chahal P
Surg Endosc 2023 Jul;37(7):5022-5044. Epub 2023 May 23 doi: 10.1007/s00464-023-10083-0. PMID: 37221416
Podda M, Gerardi C, Di Saverio S, Marino MV, Davies RJ, Pellino G, Pisanu A
Surg Endosc 2020 Jun;34(6):2390-2409. Epub 2020 Feb 18 doi: 10.1007/s00464-020-07460-4. PMID: 32072286
Beger HG, Mayer B, Rau BM
J Gastrointest Surg 2016 Jan;20(1):206-17. Epub 2015 Nov 2 doi: 10.1007/s11605-015-2981-2. PMID: 26525207
Beger HG, Nakao A, Mayer B, Poch B
Pancreatology 2015 Mar-Apr;15(2):167-78. Epub 2015 Feb 7 doi: 10.1016/j.pan.2015.01.009. PMID: 25732271

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