Carotid intimal medial thickness 1(CIMT1)

MedGen UID:: 332175
•Concept ID:: C1836302
•: Disease or Syndrome

Synonyms:	Cardiovascular Disease Risk Factor (Carotid Intimal Medial Thickness 1); CIMT1; INTIMAL MEDIAL THICKNESS OF INTERNAL CAROTID ARTERY

Gene (location): Gene(s) directly associated with this condition or phenotype.	PPARG (3p25.2)

OMIM®:	609338

Professional guidelines

PubMed

Statin treatment of children with familial hypercholesterolemia--trying to balance incomplete evidence of long-term safety and clinical accountability: are we approaching a consensus?

Vuorio A, Docherty KF, Humphries SE, Kuoppala J, Kovanen PT
Atherosclerosis 2013 Feb;226(2):315-20. Epub 2012 Oct 12 doi: 10.1016/j.atherosclerosis.2012.10.032. PMID: 23141908

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Recent clinical studies

Etiology

Lack of evidence of the correlation between plasma Asymmetrical Dimethylarginine correlation and IMT in type 2 diabetic patients with chronic vascular complication.

Fiodorenko-Dumas Z, Dumas I, Rabczynski M, Małecki R, Adamiec R, Paprocka-Borowicz M
Acta Biochim Pol 2021 Feb 5;68(1):143-149. doi: 10.18388/abp.2020_5424. PMID: 33543609

Relationship between carotid artery atherosclerosis and sulfatide in hypertensive patients.

Li G, Hu R, Gu J, Wu HZ
Genet Mol Res 2015 May 11;14(2):4840-6. doi: 10.4238/2015.May.11.16. PMID: 25966258

Markers of cardiovascular risk in patients with antiphospholipid syndrome: a meta-analysis of literature studies.

Ambrosino P, Lupoli R, Di Minno A, Iervolino S, Peluso R, Di Minno MN
Ann Med 2014 Dec;46(8):693-702. Epub 2014 Oct 13 doi: 10.3109/07853890.2014.959559. PMID: 25307359

Serum 25-hydroxyvitamin D concentration in subclinical carotid atherosclerosis.

Deleskog A, Piksasova O, Silveira A, Gertow K, Baldassarre D, Veglia F, Sennblad B, Strawbridge RJ, Larsson M, Leander K, Gigante B, Kauhanen J, Rauramaa R, Smit AJ, Mannarino E, Giral P, Gustafsson S, Östenson CG, Humphries SE, Tremoli E, de Faire U, Öhrvik J, Hamsten A
Arterioscler Thromb Vasc Biol 2013 Nov;33(11):2633-8. Epub 2013 Sep 26 doi: 10.1161/ATVBAHA.113.301593. PMID: 24072691

Pulse pressure and subclinical cardiovascular disease in the multi-ethnic study of atherosclerosis.

Winston GJ, Palmas W, Lima J, Polak JF, Bertoni AG, Burke G, Eng J, Gottesman R, Shea S
Am J Hypertens 2013 May;26(5):636-42. Epub 2013 Feb 6 doi: 10.1093/ajh/hps092. PMID: 23388832 Free PMC Article

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Diagnosis

Lack of evidence of the correlation between plasma Asymmetrical Dimethylarginine correlation and IMT in type 2 diabetic patients with chronic vascular complication.

Fiodorenko-Dumas Z, Dumas I, Rabczynski M, Małecki R, Adamiec R, Paprocka-Borowicz M
Acta Biochim Pol 2021 Feb 5;68(1):143-149. doi: 10.18388/abp.2020_5424. PMID: 33543609

Association between Serum Mg(2+) Concentrations and Cardiovascular Organ Damage in a Cohort of Adult Subjects.

Mancuso E, Perticone M, Spiga R, Averta C, Rubino M, Fiorentino TV, Miceli S, Mannino GC, Sciacqua A, Succurro E, Perticone F, Sesti G, Andreozzi F
Nutrients 2020 Apr 29;12(5) doi: 10.3390/nu12051264. PMID: 32365559 Free PMC Article

Serum levels of anticyclic citrullinated peptide antibodies, interleukin-6, tumor necrosis factor-α, and C-reactive protein are associated with increased carotid intima-media thickness: a cross-sectional analysis of a cohort of rheumatoid arthritis patients without cardiovascular risk factors.

Vázquez-Del Mercado M, Nuñez-Atahualpa L, Figueroa-Sánchez M, Gómez-Bañuelos E, Rocha-Muñoz AD, Martín-Márquez BT, Corona-Sanchez EG, Martínez-García EA, Macias-Reyes H, Gonzalez-Lopez L, Gamez-Nava JI, Navarro-Hernandez RE, Nuñez-Atahualpa MA, Andrade-Garduño J
Biomed Res Int 2015;2015:342649. Epub 2015 Mar 2 doi: 10.1155/2015/342649. PMID: 25821796 Free PMC Article

Clinical determinants of carotid intima-media thickness in patients with diabetes mellitus type 2.

Bartman W, Pierzchała K
Neurol Neurochir Pol 2012 Nov-Dec;46(6):519-28. doi: 10.5114/ninp.2012.32278. PMID: 23319219

Premature subclinical atherosclerosis in pediatric inflammatory bowel disease.

Aloi M, Tromba L, Di Nardo G, Dilillo A, Del Giudice E, Marocchi E, Viola F, Civitelli F, Berni A, Cucchiara S
J Pediatr 2012 Oct;161(4):589-94.e1. Epub 2012 May 10 doi: 10.1016/j.jpeds.2012.03.043. PMID: 22579000

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Therapy

Undercarboxylated osteocalcin as a biomarker of subclinical atherosclerosis in non-dialysis patients with chronic kidney disease.

Zhang M, Ni Z, Zhou W, Qian J
J Biomed Sci 2015 Sep 17;22(1):75. doi: 10.1186/s12929-015-0183-6. PMID: 26381729 Free PMC Article

Comparison of mercury sphygmomanometry blood pressure readings with oscillometric and central blood pressure in predicting target organ damage in youth.

Urbina EM, Khoury PR, McCoy CE, Daniels SR, Dolan LM, Kimball TR
Blood Press Monit 2015 Jun;20(3):150-6. doi: 10.1097/MBP.0000000000000110. PMID: 25647284 Free PMC Article

Rationale and design of the Kronos Early Estrogen Prevention Study (KEEPS) and the KEEPS Cognitive and Affective sub study (KEEPS Cog).

Wharton W, Gleason CE, Miller VM, Asthana S
Brain Res 2013 Jun 13;1514:12-7. Epub 2013 Apr 17 doi: 10.1016/j.brainres.2013.04.011. PMID: 23603409 Free PMC Article

Statin treatment of children with familial hypercholesterolemia--trying to balance incomplete evidence of long-term safety and clinical accountability: are we approaching a consensus?

Vuorio A, Docherty KF, Humphries SE, Kuoppala J, Kovanen PT
Atherosclerosis 2013 Feb;226(2):315-20. Epub 2012 Oct 12 doi: 10.1016/j.atherosclerosis.2012.10.032. PMID: 23141908

See all (4)

Prognosis

Comparison of mercury sphygmomanometry blood pressure readings with oscillometric and central blood pressure in predicting target organ damage in youth.

Urbina EM, Khoury PR, McCoy CE, Daniels SR, Dolan LM, Kimball TR
Blood Press Monit 2015 Jun;20(3):150-6. doi: 10.1097/MBP.0000000000000110. PMID: 25647284 Free PMC Article

Pulse pressure and subclinical cardiovascular disease in the multi-ethnic study of atherosclerosis.

Winston GJ, Palmas W, Lima J, Polak JF, Bertoni AG, Burke G, Eng J, Gottesman R, Shea S
Am J Hypertens 2013 May;26(5):636-42. Epub 2013 Feb 6 doi: 10.1093/ajh/hps092. PMID: 23388832 Free PMC Article

Psychological factors, including alexithymia, in the prediction of cardiovascular risk in HIV infected patients: results of a cohort study.

Parruti G, Vadini F, Sozio F, Mazzott E, Ursini T, Polill E, Di Stefano P, Tontodonati M, Verrocchio MC, Fulcheri M, Calella G, Santilli F, Manzoli L
PLoS One 2013;8(1):e54555. Epub 2013 Jan 22 doi: 10.1371/journal.pone.0054555. PMID: 23349927 Free PMC Article

Clinical determinants of carotid intima-media thickness in patients with diabetes mellitus type 2.

Bartman W, Pierzchała K
Neurol Neurochir Pol 2012 Nov-Dec;46(6):519-28. doi: 10.5114/ninp.2012.32278. PMID: 23319219

See all (5)