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Fetal hemoglobin quantitative trait locus 6(HBFQTL6)

MedGen UID:
462155
Concept ID:
C3150805
Finding
Synonym: HBFQTL6
 
Gene (location): KLF1 (19p13.13)
 
OMIM®: 613566

Recent clinical studies

Etiology

Manco L, Bento C, Relvas L, Cunha E, Pereira J, Moreira V, Alvarez M, Maia T, Ribeiro ML
Hemoglobin 2020 Mar;44(2):113-117. Epub 2020 Apr 22 doi: 10.1080/03630269.2020.1753766. PMID: 32319326
Lai Y, Zhou L, Yi S, Chen Y, Tang Y, Yi S, Yang Z, Wei H, Zheng C, He S
Blood Cells Mol Dis 2017 Mar;63:52-57. Epub 2017 Jan 25 doi: 10.1016/j.bcmd.2017.01.011. PMID: 28160732
Menzel S, Rooks H, Zelenika D, Mtatiro SN, Gnanakulasekaran A, Drasar E, Cox S, Liu L, Masood M, Silver N, Garner C, Vasavda N, Howard J, Makani J, Adekile A, Pace B, Spector T, Farrall M, Lathrop M, Thein SL
Ann Hum Genet 2014 Nov;78(6):434-51. Epub 2014 Jul 29 doi: 10.1111/ahg.12077. PMID: 25069958Free PMC Article
Ip HW, So CC
Crit Rev Clin Lab Sci 2013 Nov;50(6):125-41. doi: 10.3109/10408363.2013.847236. PMID: 24295057
Sivakumaran S, Agakov F, Theodoratou E, Prendergast JG, Zgaga L, Manolio T, Rudan I, McKeigue P, Wilson JF, Campbell H
Am J Hum Genet 2011 Nov 11;89(5):607-18. doi: 10.1016/j.ajhg.2011.10.004. PMID: 22077970Free PMC Article

Diagnosis

Ip HW, So CC
Crit Rev Clin Lab Sci 2013 Nov;50(6):125-41. doi: 10.3109/10408363.2013.847236. PMID: 24295057
Wahlberg K, Jiang J, Rooks H, Jawaid K, Matsuda F, Yamaguchi M, Lathrop M, Thein SL, Best S
Blood 2009 Aug 6;114(6):1254-62. Epub 2009 Jun 15 doi: 10.1182/blood-2009-03-210146. PMID: 19528534

Therapy

Adekile A
Med Princ Pract 2021;30(3):201-211. Epub 2020 Sep 4 doi: 10.1159/000511342. PMID: 32892201Free PMC Article

Prognosis

Al-Allawi N, Qadir SMA, Puehringer H, Chui DHK, Farrell JJ, Oberkanins C
Int J Lab Hematol 2019 Feb;41(1):87-93. Epub 2018 Sep 14 doi: 10.1111/ijlh.12927. PMID: 30216683
Lai Y, Zhou L, Yi S, Chen Y, Tang Y, Yi S, Yang Z, Wei H, Zheng C, He S
Blood Cells Mol Dis 2017 Mar;63:52-57. Epub 2017 Jan 25 doi: 10.1016/j.bcmd.2017.01.011. PMID: 28160732
Chan NC, Lau KM, Cheng KC, Chan NP, Ng MH
Hemoglobin 2016 Nov;40(6):400-404. Epub 2016 Nov 14 doi: 10.1080/03630269.2016.1245198. PMID: 27707011
Bhanushali AA, Patra PK, Pradhan S, Khanka SS, Singh S, Das BR
Transl Res 2015 Jun;165(6):696-703. Epub 2015 Jan 13 doi: 10.1016/j.trsl.2015.01.002. PMID: 25651163
Sivakumaran S, Agakov F, Theodoratou E, Prendergast JG, Zgaga L, Manolio T, Rudan I, McKeigue P, Wilson JF, Campbell H
Am J Hum Genet 2011 Nov 11;89(5):607-18. doi: 10.1016/j.ajhg.2011.10.004. PMID: 22077970Free PMC Article

Clinical prediction guides

Manco L, Bento C, Relvas L, Cunha E, Pereira J, Moreira V, Alvarez M, Maia T, Ribeiro ML
Hemoglobin 2020 Mar;44(2):113-117. Epub 2020 Apr 22 doi: 10.1080/03630269.2020.1753766. PMID: 32319326
Al-Allawi N, Qadir SMA, Puehringer H, Chui DHK, Farrell JJ, Oberkanins C
Int J Lab Hematol 2019 Feb;41(1):87-93. Epub 2018 Sep 14 doi: 10.1111/ijlh.12927. PMID: 30216683
Lai Y, Zhou L, Yi S, Chen Y, Tang Y, Yi S, Yang Z, Wei H, Zheng C, He S
Blood Cells Mol Dis 2017 Mar;63:52-57. Epub 2017 Jan 25 doi: 10.1016/j.bcmd.2017.01.011. PMID: 28160732
Sivakumaran S, Agakov F, Theodoratou E, Prendergast JG, Zgaga L, Manolio T, Rudan I, McKeigue P, Wilson JF, Campbell H
Am J Hum Genet 2011 Nov 11;89(5):607-18. doi: 10.1016/j.ajhg.2011.10.004. PMID: 22077970Free PMC Article
Garner C, Mitchell J, Hatzis T, Reittie J, Farrall M, Thein SL
Am J Hum Genet 1998 Jun;62(6):1468-74. doi: 10.1086/301859. PMID: 9585587Free PMC Article

Recent systematic reviews

Sivakumaran S, Agakov F, Theodoratou E, Prendergast JG, Zgaga L, Manolio T, Rudan I, McKeigue P, Wilson JF, Campbell H
Am J Hum Genet 2011 Nov 11;89(5):607-18. doi: 10.1016/j.ajhg.2011.10.004. PMID: 22077970Free PMC Article

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