nkiras1 NFKB inhibitor interacting Ras-like 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nkiras1provided by ZNC
Official Full Name: NFKB inhibitor interacting Ras-like 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-215
See related: Ensembl:ENSDARG00000099527 AllianceGenome:ZFIN:ZDB-GENE-040718-215
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92823
Summary: Predicted to enable GTP binding activity and GTPase activity. Predicted to act upstream of or within I-kappaB kinase/NF-kappaB signaling. Predicted to be located in cytoplasm. Orthologous to human NKIRAS1 (NFKB inhibitor interacting Ras like 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (17377346..17385548, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (17918781..17926983, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activating protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in Ral protein signal transduction	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: NF-kappa-B inhibitor-interacting Ras-like protein 1

Names: I-kappa-B-interacting Ras-like protein 1; kappa B-Ras protein 1; kappaB-Ras1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001100076.1 → NP_001093546.1 NF-kappa-B inhibitor-interacting Ras-like protein 1

See identical proteins and their annotated locations for NP_001093546.1

Status: PROVISIONAL

Source sequence(s)

BX927163

UniProtKB/Swiss-Prot

A5PMZ9, Q6DGQ1

Related

ENSDARP00000135507.1, ENSDART00000162383.2

Conserved Domains (2) summary

pfam00071
Location:6 → 168

Ras; Ras family

cl21455
Location:6 → 168

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases