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Ndufb4b NADH:ubiquinone oxidoreductase subunit B4B [ Mus musculus (house mouse) ]

Gene ID: 100042503, updated on 8-Feb-2024

Summary

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Official Symbol
Ndufb4bprovided by MGI
Official Full Name
NADH:ubiquinone oxidoreductase subunit B4Bprovided by MGI
Primary source
MGI:MGI:3782046
See related
Ensembl:ENSMUSG00000120425 AllianceGenome:MGI:3782046
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm3873
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly and response to oxidative stress. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of mitochondrial respiratory chain complex I. Orthologous to human NDUFB4 (NADH:ubiquinone oxidoreductase subunit B4). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Ndufb4b in Genome Data Viewer
Location:
19 B; 19 19.95 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (25010472..25010942)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (25033108..25033578)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene forkhead box D4 Neighboring gene STARR-seq mESC enhancer starr_45808 Neighboring gene Zn regulated GTPase metalloprotein activator 1 Neighboring gene microRNA 3084-1 Neighboring gene STARR-positive B cell enhancer mm9_chr19:25033055-25033356 Neighboring gene STARR-positive B cell enhancer ABC_E7639 Neighboring gene STARR-positive B cell enhancer ABC_E5693 Neighboring gene STARR-seq mESC enhancer starr_45809 Neighboring gene dedicator of cytokinesis 8 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:25126893-25127076 Neighboring gene STARR-positive B cell enhancer ABC_E1974 Neighboring gene predicted gene, 34235 Neighboring gene predicted gene, 34186

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization. Watkins DS, et al. Proteomes, 2018 Dec 17. PMID 30562941, Free PMC Article
  2. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex I assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in response to oxidative stress ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial respiratory chain complex I ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    25010472..25010942
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001478443.6 → XP_001478493.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

    See identical proteins and their annotated locations for XP_001478493.1

    UniProtKB/Swiss-Prot
    Q9CQC7
    UniProtKB/TrEMBL
    Q4VAE8
    Related
    ENSMUST00000243237.1
    Conserved Domains (1) summary
    pfam07225
    Location:5 → 128
    NDUF_B4; NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
Nucleotide Protein
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