U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MIR4692 microRNA 4692 [ Homo sapiens (human) ]

Gene ID: 100616410, updated on 10-Oct-2023

Summary

Go to the top of the page Help
Official Symbol
MIR4692provided by HGNC
Official Full Name
microRNA 4692provided by HGNC
Primary source
HGNC:HGNC:41856
See related
Ensembl:ENSG00000265064 miRBase:MI0017325; AllianceGenome:HGNC:41856
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
11q13.4
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (72783530..72783592)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (72711757..72711819)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (72494575..72494637)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3724 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:72415096-72415932 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:72417010-72417596 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:72420686-72421388 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:72423687-72424267 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:72424849-72425428 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:72428169-72428669 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:72428974-72429474 Neighboring gene ARAP1 antisense RNA 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5194 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3725 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5195 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5196 Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 Neighboring gene ribosomal protein S12 pseudogene 20 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5197 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5198 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:72452199-72452976 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:72453754-72454530 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5201 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5202 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3726 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5203 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5204 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:72485809-72486308 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3727 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3728 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:72493384-72494086 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:72497138-72498136 Neighboring gene StAR related lipid transfer domain containing 10 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:72498137-72499133 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:72503217-72503716 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5206 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:72509227-72509964 Neighboring gene uncharacterized LOC107984421 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3729 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5207 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5208 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3730 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3731 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5209 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3732 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5210 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5211 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5212 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:72537383-72537883 Neighboring gene autophagy related 16 like 2 Neighboring gene FCH and double SH3 domains 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. Persson H, et al. Cancer Res, 2011 Jan 1. PMID 21199797
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

Go to the top of the page Help

Other Names

  • hsa-mir-4692

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_039841.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AP002381
    Related
    ENST00000583200.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    72783530..72783592
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    72711757..72711819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Miscellaneous