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Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100753689, updated on 8-Mar-2024

Summary

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Gene symbol
Dhtkd1
Gene description
dehydrogenase E1 and transketolase domain containing 1
Locus tag
I79_001790
See related
Ensembl:ENSCGRG00015020176
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
17
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613621.1 (1364528..1401337)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 3 NC_048596.1 (223084298..223121174, complement)

NW_003613621.1Genomic Context describing neighboring genes Neighboring gene UPF2 regulator of nonsense mediated mRNA decay Neighboring gene uncharacterized LOC113834623 Neighboring gene SEC61 translocon subunit alpha 2 Neighboring gene nudix hydrolase 5 Neighboring gene cell division cycle 123

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxoglutarate dehydrogenase (succinyl-transferring) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables thiamine pyrophosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
Names
putative 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613621.1 Reference CriGri_1.0 Primary Assembly

    Range
    1364528..1401337
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003496423.5 → XP_003496471.1  probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C2M9M1
    Conserved Domains (4) summary
    PRK09404
    Location:36 → 914
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed
    cd02016
    Location:176 → 449
    TPP_E1_OGDC_like; Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of ...
    pfam02779
    Location:569 → 771
    Transket_pyr; Transketolase, pyrimidine binding domain
    pfam16870
    Location:778 → 918
    OxoGdeHyase_C; 2-oxoglutarate dehydrogenase C-terminal

  2. XM_035460684.1 → XP_035316575.1  probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A9J7GUK1
    Conserved Domains (1) summary
    cl39092
    Location:36 → 771
    SucA; 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes [Energy production and conversion]

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048596.1 Alternate CriGri-PICRH-1.0

    Range
    223084298..223121174 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027405175.2 → XP_027260976.1  probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C2M9M1
    Related
    ENSCGRP00015026632.1, ENSCGRT00015032616.2

  2. XM_035442831.1 → XP_035298722.1  probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A9J7GUK1
    Conserved Domains (1) summary
    cl39092
    Location:36 → 771
    SucA; 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes [Energy production and conversion]
Nucleotide Protein Strain
Heading Accession and Version

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