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Dgka diacylglycerol kinase alpha [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100769779, updated on 8-Mar-2024

Summary

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Gene symbol
Dgka
Gene description
diacylglycerol kinase alpha
Locus tag
I79_013512
See related
Ensembl:ENSCGRG00015028186
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
26
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614217.1 (758177..783587, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276806.1 (129164086..129189667)

NW_003614217.1Genomic Context describing neighboring genes Neighboring gene cyclin dependent kinase 2 Neighboring gene premelanosome protein Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene matrix metallopeptidase 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein kinase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase alpha
Names
diacylglycerol kinase, alpha 80kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614217.1 Reference CriGri_1.0 Primary Assembly

    Range
    758177..783587 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035458207.1 → XP_035314098.1  diacylglycerol kinase alpha isoform X3

    UniProtKB/TrEMBL
    A0A9J7H7Q6
    Conserved Domains (2) summary
    smart00045
    Location:175 → 356
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:34 → 154
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)

  2. XM_007646710.3 → XP_007644900.1  diacylglycerol kinase alpha isoform X1

    See identical proteins and their annotated locations for XP_007644900.1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7
    Conserved Domains (6) summary
    smart00045
    Location:516 → 697
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:375 → 495
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:116 → 185
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:208 → 256
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:117 → 181
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:7 → 112
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  3. XM_007646711.3 → XP_007644901.1  diacylglycerol kinase alpha isoform X1

    See identical proteins and their annotated locations for XP_007644901.1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7
    Conserved Domains (6) summary
    smart00045
    Location:516 → 697
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:375 → 495
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:116 → 185
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:208 → 256
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:117 → 181
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:7 → 112
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  4. XM_003506199.5 → XP_003506247.1  diacylglycerol kinase alpha isoform X1

    See identical proteins and their annotated locations for XP_003506247.1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7
    Conserved Domains (6) summary
    smart00045
    Location:516 → 697
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:375 → 495
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:116 → 185
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:208 → 256
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:117 → 181
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:7 → 112
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  5. XM_027439148.2 → XP_027294949.1  diacylglycerol kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7

  6. XM_007646708.4 → XP_007644898.1  diacylglycerol kinase alpha isoform X1

    See identical proteins and their annotated locations for XP_007644898.1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7
    Conserved Domains (6) summary
    smart00045
    Location:516 → 697
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:375 → 495
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:116 → 185
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:208 → 256
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:117 → 181
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:7 → 112
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  7. XM_007646712.4 → XP_007644902.1  diacylglycerol kinase alpha isoform X2

    See identical proteins and their annotated locations for XP_007644902.1

    UniProtKB/TrEMBL
    A0A9J7J745, G3HRK7
    Conserved Domains (6) summary
    smart00045
    Location:476 → 657
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:335 → 455
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:76 → 145
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:168 → 216
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:77 → 141
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:1 → 72
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  8. XM_007646707.4 → XP_007644897.1  diacylglycerol kinase alpha isoform X1

    See identical proteins and their annotated locations for XP_007644897.1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7
    Conserved Domains (6) summary
    smart00045
    Location:516 → 697
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:375 → 495
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:116 → 185
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:208 → 256
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:117 → 181
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:7 → 112
    DAG_kinase_N; Diacylglycerol kinase N-terminus

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276806.1 Alternate CriGri-PICRH-1.0

    Range
    129164086..129189667
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035450625.1 → XP_035306516.1  diacylglycerol kinase alpha isoform X3

    UniProtKB/TrEMBL
    A0A9J7H7Q6
    Conserved Domains (2) summary
    smart00045
    Location:175 → 356
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:34 → 154
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)

  2. XM_027392140.2 → XP_027247941.1  diacylglycerol kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7

  3. XM_027392139.2 → XP_027247940.1  diacylglycerol kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7

  4. XM_027392134.2 → XP_027247935.1  diacylglycerol kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7
    Related
    ENSCGRP00015037616.2, ENSCGRT00015045871.2

  5. XM_027392136.2 → XP_027247937.1  diacylglycerol kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7

  6. XM_027392133.2 → XP_027247934.1  diacylglycerol kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7
    Related
    ENSCGRP00015037620.2, ENSCGRT00015045875.2

  7. XM_027392138.2 → XP_027247939.1  diacylglycerol kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A9J7F4Y1, G3HRK7

  8. XM_027392141.2 → XP_027247942.1  diacylglycerol kinase alpha isoform X2

    UniProtKB/TrEMBL
    A0A9J7J745, G3HRK7
Nucleotide Protein Strain
Heading Accession and Version

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