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LOC100911486 multiple epidermal growth factor-like domains protein 6-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 100911486, discontinued on 6-Mar-2021

Summary

Symbol
LOC100911486provided by RGD
Full Name
multiple epidermal growth factor-like domains protein 6-likeprovided by RGD
Primary source
RGD:6492904
Gene type
protein coding
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Annotation information
Note: LOC100911486 appears to be a duplicate placement of Megf6 (GeneID: 65049) on Rnor_6.0 that is not present on Rn_Celera (Annotation Release 105) and not supported by synteny in mouse and human. BLASTing LOC100911486 XM_008764417.1 and Megf6 NM_022955.1 against the rat genome shows best hits to NC_005104.4 on Rnor_6.0 at locations where LOC100911486 and Megf6 are annotated and to AC_000073.1 on Rn_Celera only at location where Megf6 is annotated (Annotation Release 105). 2-sequence BLAST of Megf6 NM_022955.1 against LOC100911486 XM_008764417.1 shows high sequence identity (79% coverage, 99% identity). Although five components underlie LOC100911486, AABR07050625.1 includes the genomic region with the majority of exons that comprise XM_008764417.1. BLASTing AABR07050625.1 against the rat genome shows best hits to NC_005104.4 on Rnor_6.0 at the location where LOC100911486 is annotated (hitting itself) and the location where Megf6 is annotated. 2-sequence BLAST of AABR07050625.1 against Megf6 underlying component AABR07050628.1 shows 99% sequence identity across stretch of ~25 kb. [26 Mar 2015]
Expression
Biased expression in Lung (RPKM 90.4), Heart (RPKM 19.0) and 8 other tissues See more
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Genomic context

Location:
5q36
Exon count:
35
Annotation release Status Assembly Chr Location
106 latest, but not current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (171478247..171571810)

Genomic regions, transcripts, and products

Genomic Sequence:
NC_005104.4 Chromosome 5 Reference Rnor_6.0 Primary Assembly

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Names
multiple epidermal growth factor-like domains protein 6-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 (NOTE: not current)

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

    Range
    171478247..171571810
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008764417.1XP_008762639.1