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LINC02273 long intergenic non-protein coding RNA 2273 [ Homo sapiens (human) ]

Gene ID: 100996286, updated on 10-Oct-2023

Summary

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Official Symbol
LINC02273provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 2273provided by HGNC
Primary source
HGNC:HGNC:53188
See related
Ensembl:ENSG00000245954 AllianceGenome:HGNC:53188
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in lymph node (RPKM 3.2), appendix (RPKM 1.5) and 5 other tissues See more
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Genomic context

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See LINC02273 in Genome Data Viewer
Location:
4q31.3
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (152100753..152104720)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (155423860..155427846)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (153021905..153025872)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 3074 Neighboring gene RNA, 5S ribosomal pseudogene 169 Neighboring gene NANOG hESC enhancer GRCh37_chr4:152925827-152926328 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22025 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:152945037-152945536 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15749 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22026 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22027 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22028 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:153021562-153022062 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:153022063-153022563 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr4:153022858-153024057 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr4:153027165-153028364 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15750 Neighboring gene uncharacterized LOC124900800 Neighboring gene uncharacterized LOC105377489

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LINC02273 drives breast cancer metastasis by epigenetically increasing AGR2 transcription. Xiu B, et al. Mol Cancer, 2019 Dec 19. PMID 31856843, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_121627.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AC079340
    Related
    ENST00000499452.2

  2. NR_121628.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' terminal exon, resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    BC040914, BU617226, CB986668
    Related
    ENST00000509332.7

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    152100753..152104720
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    155423860..155427846
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases