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Znf454 zinc finger protein 454 [ Rattus norvegicus (Norway rat) ]

Gene ID: 102555919, updated on 11-Apr-2024

Summary

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Official Symbol
Znf454provided by RGD
Official Full Name
zinc finger protein 454provided by RGD
Primary source
RGD:7529496
See related
Ensembl:ENSRNOG00000029678 AllianceGenome:RGD:7529496
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Zfp454
Summary
Predicted to enable sequence-specific double-stranded DNA binding activity. Orthologous to human ZNF454 (zinc finger protein 454). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 16.6), Adrenal (RPKM 7.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Znf454 in Genome Data Viewer
Location:
10q22
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (35684741..35701281, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (35183729..35200450, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 879 Neighboring gene glutamate metabotropic receptor 6 Neighboring gene zinc finger protein 2 Neighboring gene zinc finger protein 354B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger protein 454

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    35684741..35701281 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039087185.2 → XP_038943113.1  zinc finger protein 454 isoform X2

    UniProtKB/TrEMBL
    A6HE31, F1MAM2
    Related
    ENSRNOP00000031832.7
    Conserved Domains (4) summary
    smart00349
    Location:14 → 66
    KRAB; krueppel associated box
    COG5048
    Location:214 → 518
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:216 → 236
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:153 → 169
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_039087183.2 → XP_038943111.1  zinc finger protein 454 isoform X1

    Conserved Domains (4) summary
    smart00349
    Location:14 → 67
    KRAB; krueppel associated box
    COG5048
    Location:215 → 519
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:217 → 237
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:154 → 170
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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