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Acte1 actin, epsilon 1 [ Mus musculus (house mouse) ]

Gene ID: 102636989, updated on 11-Apr-2024

Summary

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Official Symbol
Acte1provided by MGI
Official Full Name
actin, epsilon 1provided by MGI
Primary source
MGI:MGI:2685344
See related
Ensembl:ENSMUSG00000031085 AllianceGenome:MGI:2685344
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm498
Summary
Predicted to be part of dynactin complex. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 58.2) See more
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Genomic context

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Location:
7 F5; 7 88.33 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (143420575..143453780)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (143866838..143900044)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene NAD synthetase 1 Neighboring gene STARR-positive B cell enhancer ABC_E1750 Neighboring gene STARR-positive B cell enhancer ABC_E2257 Neighboring gene STARR-positive B cell enhancer ABC_E3763 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:151023918-151024190 Neighboring gene 7-dehydrocholesterol reductase Neighboring gene STARR-seq mESC enhancer starr_20537 Neighboring gene microRNA 6404 Neighboring gene predicted gene, 34445

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
actin, epsilon 1
Names
actin-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001369834.1 → NP_001356763.1  actin, epsilon 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC133502
    UniProtKB/TrEMBL
    J3QK70
    Conserved Domains (1) summary
    cl17037
    Location:2 → 382
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  2. NM_001369835.1 → NP_001356764.1  actin, epsilon 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC133502
    Consensus CDS
    CCDS90361.1
    UniProtKB/TrEMBL
    D3YYH9, J3QK70
    Related
    ENSMUSP00000115809.2, ENSMUST00000152910.3
    Conserved Domains (1) summary
    cl17037
    Location:2 → 372
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  3. NM_001369836.1 → NP_001356765.1  actin, epsilon 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC133502
    Consensus CDS
    CCDS90360.1
    UniProtKB/TrEMBL
    A0A140LHA3, J3QK70
    Related
    ENSMUSP00000146335.2, ENSMUST00000207630.2
    Conserved Domains (1) summary
    cl17037
    Location:2 → 370
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  4. NM_001369837.1 → NP_001356766.1  actin, epsilon 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC133502
    UniProtKB/TrEMBL
    J3QK70
    Conserved Domains (1) summary
    cl17037
    Location:3 → 308
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    143420575..143453780
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030241966.1 → XP_030097826.1  actin, epsilon 1 isoform X4

    Conserved Domains (1) summary
    cl17037
    Location:2 → 216
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  2. XM_006508669.5 → XP_006508732.1  actin, epsilon 1 isoform X2

    UniProtKB/TrEMBL
    J3QK70
    Conserved Domains (1) summary
    cl17037
    Location:2 → 275
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  3. XM_030241967.1 → XP_030097827.1  actin, epsilon 1 isoform X4

    Conserved Domains (1) summary
    cl17037
    Location:2 → 216
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  4. XM_006508666.1 → XP_006508729.1  actin, epsilon 1 isoform X1

    UniProtKB/TrEMBL
    J3QK70
    Conserved Domains (1) summary
    cl17037
    Location:2 → 380
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  5. XM_030241965.1 → XP_030097825.1  actin, epsilon 1 isoform X4

    Conserved Domains (1) summary
    cl17037
    Location:2 → 216
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  6. XM_030241964.1 → XP_030097824.1  actin, epsilon 1 isoform X3

    Conserved Domains (1) summary
    cl17037
    Location:1 → 256
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  7. XM_006508671.2 → XP_006508734.1  actin, epsilon 1 isoform X4

    See identical proteins and their annotated locations for XP_006508734.1

    Conserved Domains (1) summary
    cl17037
    Location:2 → 216
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  8. XM_006508672.4 → XP_006508735.1  actin, epsilon 1 isoform X4

    See identical proteins and their annotated locations for XP_006508735.1

    Conserved Domains (1) summary
    cl17037
    Location:2 → 216
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
Nucleotide Protein
Heading Accession and Version

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