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HCK HCK proto-oncogene, Src family tyrosine kinase [ Macaca nemestrina (pig-tailed macaque) ]

Gene ID: 105496179, updated on 11-Apr-2024

Summary

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Gene symbol
HCK
Gene description
HCK proto-oncogene, Src family tyrosine kinase
See related
Ensembl:ENSMNEG00000042056
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca nemestrina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012011800.1 (4426789..4480492)

NW_012011800.1Genomic Context describing neighboring genes Neighboring gene CCM2 like scaffold protein Neighboring gene uncharacterized LOC105496176 Neighboring gene uncharacterized LOC105496178 Neighboring gene transmembrane 9 superfamily member 4 Neighboring gene putative testis-specific Y-encoded-like protein 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012011800 Unplaced Scaffold Reference Mnem_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase HCK

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnem_1.0

Genomic

  1. NW_012011800.1 Reference Mnem_1.0

    Range
    4426789..4480492
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011766330.1 → XP_011764632.1  tyrosine-protein kinase HCK

    See identical proteins and their annotated locations for XP_011764632.1

    UniProtKB/TrEMBL
    A0A2K6DQ69
    Related
    ENSMNEP00000038056.1, ENSMNET00000062529.1
    Conserved Domains (3) summary
    cd10363
    Location:118 → 221
    SH2_Src_HCK; Src homology 2 (SH2) domain found in HCK
    cl17036
    Location:60 → 115
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:232 → 502
    PKc_like; Protein Kinases, catalytic domain

  2. XM_011766331.2 → XP_011764633.1  tyrosine-protein kinase HCK

    See identical proteins and their annotated locations for XP_011764633.1

    UniProtKB/TrEMBL
    A0A2K6DQ69
    Conserved Domains (3) summary
    cd10363
    Location:118 → 221
    SH2_Src_HCK; Src homology 2 (SH2) domain found in HCK
    cl17036
    Location:60 → 115
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:232 → 502
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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