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Unc119b unc-119 lipid binding chaperone B [ Mus musculus (house mouse) ]

Gene ID: 106840, updated on 9-May-2024

Summary

Official Symbol
Unc119bprovided by MGI
Official Full Name
unc-119 lipid binding chaperone Bprovided by MGI
Primary source
MGI:MGI:2147162
See related
Ensembl:ENSMUSG00000046562 AllianceGenome:MGI:2147162
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable lipid binding activity. Predicted to be involved in cilium assembly; lipoprotein transport; and nervous system development. Predicted to act upstream of or within cell projection organization and protein transport. Predicted to be located in ciliary transition zone. Predicted to be active in cilium. Is expressed in several structures, including central nervous system; genitourinary system; gut; respiratory system; and sensory organ. Orthologous to human UNC119B (unc-119 lipid binding chaperone B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in kidney adult (RPKM 45.6), genital fat pad adult (RPKM 26.8) and 28 other tissues See more
Orthologs
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Genomic context

See Unc119b in Genome Data Viewer
Location:
5 F; 5 55.99 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (115260625..115273034, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (115122566..115134975, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L37, retrotransposed Neighboring gene acyl-Coenzyme A dehydrogenase, short chain Neighboring gene STARR-positive B cell enhancer ABC_E10342 Neighboring gene STARR-seq mESC enhancer starr_14100 Neighboring gene malectin Neighboring gene STARR-positive B cell enhancer ABC_E1058 Neighboring gene STARR-seq mESC enhancer starr_14105 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:115617496-115617679 Neighboring gene calcium binding protein 1 Neighboring gene STARR-seq mESC enhancer starr_14108 Neighboring gene predicted gene, 35515

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables lipid binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell projection organization IEA
Inferred from Electronic Annotation
more info
 
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cilium assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in lipoprotein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in lipoprotein transport ISO
Inferred from Sequence Orthology
more info
 
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in ciliary transition zone ISO
Inferred from Sequence Orthology
more info
 
is_active_in cilium IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein unc-119 homolog B
Names
unc-119 homolog B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175352.4NP_780561.1  protein unc-119 homolog B

    See identical proteins and their annotated locations for NP_780561.1

    Status: PROVISIONAL

    Source sequence(s)
    AC119205
    Consensus CDS
    CCDS19580.1
    UniProtKB/Swiss-Prot
    Q14BY8, Q8BRC4, Q8C4B4, Q922B4
    Related
    ENSMUSP00000055475.6, ENSMUST00000060798.6
    Conserved Domains (1) summary
    pfam05351
    Location:88247
    GMP_PDE_delta; GMP-PDE, delta subunit

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    115260625..115273034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)