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lpp major outer membrane lipoprotein [ Yersinia pestis CO92 ]

Gene ID: 1175228, discontinued on 20-Mar-2020
  • This record was discontinued.

Summary

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Gene symbol
lpp
Gene description
major outer membrane lipoprotein
Locus tag
YPO2394
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Yersinia pestis CO92 (strain: CO92, biovar: Orientalis)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Yersiniaceae; Yersinia
Also known as
mlpA
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Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003143.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. deletion of the ail gene from the Deltalpp DeltamsbB double mutant severely attenuated Y. pestis CO92 to evoke pneumonic plague in a mouse model while retaining the required immunogenicity needed for subsequent protection against infection.
    Title: Combinational deletion of three membrane protein-encoding genes highly attenuates yersinia pestis while retaining immunogenicity in a mouse model of pneumonic plague.
  2. These data indicated that a significant attenuation in bacterial virulence occurred in a mouse model of pneumonic plague when both the lpp gene and the virulence plasmid pPCP1 encoding the pla gene were deleted from Yersinia pestis.
    Title: Deletion of Braun lipoprotein gene (lpp) and curing of plasmid pPCP1 dramatically alter the virulence of Yersinia pestis CO92 in a mouse model of pneumonic plague.
Submit: New GeneRIF Correction

General gene information

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Miscellaneous features

  • Loc: 2691327-2691359 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. inference = protein motif:ProSite:PS00013

General protein information

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Names
major outer membrane lipoprotein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003143.1 Reference assembly

    Range
    2691297..2691533
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_002347360.1 major outer membrane lipoprotein [Yersinia pestis CO92]

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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