Baalc brain and acute leukemia, cytoplasmic [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Baalcprovided by MGI
Official Full Name: brain and acute leukemia, cytoplasmicprovided by MGI
Primary source: MGI:MGI:1928704
See related: Ensembl:ENSMUSG00000022296 AllianceGenome:MGI:1928704
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2810457D07Rik
Summary: Located in cytoplasm. Is expressed in central nervous system and retina. Orthologous to human BAALC (BAALC binder of MAP3K1 and KLF4). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in frontal lobe adult (RPKM 33.0), cortex adult (RPKM 32.4) and 3 other tissues See more
Orthologs: human all
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Genomic context

Location:: 15 B3.1; 15 15.18 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (38739763..38814659)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (38933909..38951264)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

BAALC/Baalc is a marker of the mesodermal lineage, especially muscle.
Title: Baalc, a marker of mesoderm and muscle.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Gene trapped (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISO Inferred from Sequence Orthology more info	PubMed
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in neuron projection	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in sarcoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: brain and acute leukemia cytoplasmic protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_080640.6 → NP_542371.1 brain and acute leukemia cytoplasmic protein isoform 1-6-8

See identical proteins and their annotated locations for NP_542371.1

Status: VALIDATED

Source sequence(s)

AC164883, FO082315

UniProtKB/Swiss-Prot

A9JR49, Q8VBS8, Q8VHV1, Q9CYS9

Related

ENSMUSP00000154447.3, ENSMUST00000226440.3

Conserved Domains (1) summary

pfam06989
Location:1 → 49

BAALC_N; BAALC N-terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000081.7 Reference GRCm39 C57BL/6J

Range

38739763..38814659

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036159094.1 → XP_036014987.1 brain and acute leukemia cytoplasmic protein isoform X3

Related

ENSMUSP00000159442.2, ENSMUST00000239553.1

Conserved Domains (1) summary

pfam06989
Location:1 → 50

BAALC_N; BAALC N-terminus
XM_036159093.1 → XP_036014986.1 brain and acute leukemia cytoplasmic protein isoform X2

Conserved Domains (1) summary

pfam06989
Location:1 → 50

BAALC_N; BAALC N-terminus
XM_036159092.1 → XP_036014985.1 brain and acute leukemia cytoplasmic protein isoform X1

Related

ENSMUSP00000132788.2, ENSMUST00000163313.3