U.S. flag

An official website of the United States government

gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4 [ Caenorhabditis elegans ]

Gene ID: 174578, updated on 9-Dec-2024

Summary

Official Symbol
gpd-4
Official Full Name
Glyceraldehyde-3-phosphate dehydrogenase 4
Primary source
WormBase:WBGene00001686
Locus tag
CELE_F33H1.2
See related
AllianceGenome:WB:WBGene00001686
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See gpd-4 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (10171268..10172498)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein Neighboring gene RFX-like transcription factor daf-19 Neighboring gene ncRNA Neighboring gene Ww (WW) domain Binding Protein Neighboring gene C2H2-type domain-containing protein

Interactions

General gene information

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in glucose metabolic process  
involved_in glycolytic process  
involved_in glycolytic process  
Component Evidence Code Pubs
located_in cytoplasm  
is_active_in cytosol  

General protein information

Preferred Names
Glyceraldehyde-3-phosphate dehydrogenase 4
NP_496192.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    10171268..10172498
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063791.8NP_496192.1  Glyceraldehyde-3-phosphate dehydrogenase 4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496192.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P17331
    Conserved Domains (3) summary
    PTZ00023
    Location:6337
    PTZ00023; glyceraldehyde-3-phosphate dehydrogenase; Provisional
    pfam00044
    Location:5158
    Gp_dh_N; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
    pfam02800
    Location:163320
    Gp_dh_C; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
External link. Please review our privacy policy.