eef-1A.1 Elongation factor 1-alpha [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: eef-1A.1
Gene description: Elongation factor 1-alpha
Primary source: WormBase:WBGene00001168
Locus tag: CELE_F31E3.5
See related: AllianceGenome:WB:WBGene00001168
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Enables GTPase activity. Predicted to be involved in translational elongation. Predicted to be located in cytoplasm. Is expressed in body wall musculature; intestine; and pharynx. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:: chromosome: III

Exon count:: 4

Sequence:: Chromosome: III; NC_003281.10 (6970026..6971712, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F31E3.5 (e-PCR)
- UniSTS:310051

F31E3.3 (e-PCR)
- UniSTS:314173

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IDA Inferred from Direct Assay more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables translation elongation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation elongation factor activity	IEA Inferred from Electronic Annotation more info
enables translation factor activity, RNA binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in translation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translation	IEA Inferred from Electronic Annotation more info
involved_in translational elongation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translational elongation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Elongation factor 1-alpha

NP_498520.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

6970026..6971712 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066119.9 → NP_498520.1 Elongation factor 1-alpha [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498520.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P53013

Conserved Domains (4) summary

PTZ00141
Location:1 → 461

PTZ00141; elongation factor 1- alpha; Provisional

cd01883
Location:9 → 239

EF1_alpha; Elongation Factor 1-alpha (EF1-alpha) protein family

cd03693
Location:242 → 332

EF1_alpha_II; Domain II of elongation factor 1-alpha

cd03705
Location:335 → 438

EF1_alpha_III; Domain III of Elongation Factor 1