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Cep19 centrosomal protein 19 [ Rattus norvegicus (Norway rat) ]

Gene ID: 192229, updated on 13-Apr-2024

Summary

Official Symbol
Cep19provided by RGD
Official Full Name
centrosomal protein 19provided by RGD
Primary source
RGD:621352
See related
Ensembl:ENSRNOG00000024924 AllianceGenome:RGD:621352
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD621352
Summary
Predicted to be involved in microtubule anchoring at centrosome and vesicle targeting, trans-Golgi to periciliary membrane compartment. Predicted to be located in cilium. Predicted to be active in microtubule cytoskeleton. Orthologous to human CEP19 (centrosomal protein 19). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 283.7), Heart (RPKM 243.5) and 9 other tissues See more
Orthologs
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Genomic context

See Cep19 in Genome Data Viewer
Location:
11q22
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (82182868..82192134, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (68677869..68687117, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (71921713..71938335, complement)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481090 Neighboring gene negative regulator of reactive oxygen species Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class X Neighboring gene small nucleolar RNA SNORA17 Neighboring gene p21 (RAC1) activated kinase 2 Neighboring gene SUMO specific peptidase 5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cilium assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in cilium assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in microtubule anchoring at centrosome IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in microtubule anchoring at centrosome IEA
Inferred from Electronic Annotation
more info
 
involved_in microtubule anchoring at centrosome ISO
Inferred from Sequence Orthology
more info
 
involved_in microtubule anchoring at centrosome ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment ISO
Inferred from Sequence Orthology
more info
 
involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centriole IEA
Inferred from Electronic Annotation
more info
 
located_in centriole ISO
Inferred from Sequence Orthology
more info
 
located_in centriole ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in ciliary basal body IEA
Inferred from Electronic Annotation
more info
 
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
 
located_in ciliary basal body ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cilium ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
 
located_in spindle pole ISO
Inferred from Sequence Orthology
more info
 
located_in spindle pole ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
centrosomal protein of 19 kDa
Names
testis specific protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138865.3NP_620220.2  centrosomal protein of 19 kDa

    See identical proteins and their annotated locations for NP_620220.2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000011
    UniProtKB/TrEMBL
    A6IRT5, A6IRT6, G3V974
    Conserved Domains (1) summary
    pfam14933
    Location:18168
    CEP19; CEP19-like protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    82182868..82192134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008768697.4XP_008766919.1  centrosomal protein of 19 kDa isoform X1

    See identical proteins and their annotated locations for XP_008766919.1

    UniProtKB/TrEMBL
    A6IRT5, A6IRT6, G3V974
    Conserved Domains (1) summary
    pfam14933
    Location:18168
    CEP19; CEP19-like protein
  2. XM_008768696.4XP_008766918.1  centrosomal protein of 19 kDa isoform X1

    See identical proteins and their annotated locations for XP_008766918.1

    UniProtKB/TrEMBL
    A6IRT5, A6IRT6, G3V974
    Related
    ENSRNOP00000038182.1
    Conserved Domains (1) summary
    pfam14933
    Location:18168
    CEP19; CEP19-like protein